Tài liệu Báo cáo Y học: Short peptides are not reliable models of thermodynamic and kinetic properties of the N-terminal metal binding site in serum albumin doc

Tài liệu Báo cáo Y học: Short peptides are not reliable models of thermodynamic and kinetic properties of the N-terminal metal binding site in serum albumin doc

Tài liệu Báo cáo Y học: Short peptides are not reliable models of thermodynamic and kinetic properties of the N-terminal metal binding site in serum albumin doc

... Short peptides are not reliable models of thermodynamic and kinetic properties of the N-terminal metal binding site in serum albumin Magdalena Sokolowska 1 , Artur Krezel 1 , Marcin Dyba 1 , ... comparative study of thermodynamic and kinetic aspects of Cu(II) and Ni(II) binding at the N-terminal b inding site of human and bovine...
Ngày tải lên : 22/02/2014, 04:20
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Tài liệu Báo cáo Y học: Transactivation domains are not functionally conserved between vertebrate and invertebrate serum response factors potx

Tài liệu Báo cáo Y học: Transactivation domains are not functionally conserved between vertebrate and invertebrate serum response factors potx

... transcription. In summary, the data obtained in this study indicate the conservation of the SRF DNA -binding and dimerization domains during evolution and the divergence of the transactivation domain. These ... C-terminal regions did not acti- vate CA promoter and strongly repressed the c-fos promoter, independently of the origin of the N-terminal region...
Ngày tải lên : 22/02/2014, 07:20
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Tài liệu Báo cáo khoa học: "Which words are hard to recognize? Prosodic, lexical, and disfluency factors that increase ASR error rates" ppt

Tài liệu Báo cáo khoa học: "Which words are hard to recognize? Prosodic, lexical, and disfluency factors that increase ASR error rates" ppt

... University {sgwater,jurafsky,manning}@stanford.edu Abstract Many factors are thought to increase the chances of misrecognizing a word in ASR, including low frequency, nearby disfluencies, short duration, and being at the start of a turn. However, few of these ... initial repetitions.) 3.2.1 Disfluency features Perhaps the most interesting result in Table 2 is that the ef...
Ngày tải lên : 20/02/2014, 09:20
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Tài liệu Báo cáo Y học: BIGH3 (TGFBI) Arg124 mutations influence the amyloid conversion of related peptides in vitro Implications in the BIGH3-linked corneal dystrophies pptx

Tài liệu Báo cáo Y học: BIGH3 (TGFBI) Arg124 mutations influence the amyloid conversion of related peptides in vitro Implications in the BIGH3-linked corneal dystrophies pptx

... amyloid from the C110)131 peptide. Role of the NH 2 -terminal sequence The role of the NH 2 -terminal sequence of the 124 centered peptides included in this study was analyzed by comparing the ... determination of the peptides by FT-IR spectroscopy in D 2 O. Spectrograms of solutions containing the same peptides included in Fig. 4 were analyzed in D 2 O...
Ngày tải lên : 21/02/2014, 01:21
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Tài liệu Báo cáo Y học: Interaction of decorin with CNBr peptides from collagens I and II Evidence for multiple binding sites and essential lysyl residues in collagen pot

Tài liệu Báo cáo Y học: Interaction of decorin with CNBr peptides from collagens I and II Evidence for multiple binding sites and essential lysyl residues in collagen pot

... the in uence on d ecorin binding of chemical modi- fication of Lys and Hyl side chains of collagens and peptides. Derivatizations that eliminate the positive charge of Lys/Hyl eliminate the binding ... of collagens and their CNBr peptides demonstrated that acetylation eliminates their binding to decorin. Lys/Hyl side chains are therefore present at, or very ne...
Ngày tải lên : 21/02/2014, 15:20
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Tài liệu Báo cáo Y học: NMR-based determination of the binding epitope and conformational analysis of MUC-1 glycopeptides and peptides bound to the breast cancer-selective monoclonal antibody SM3 pptx

Tài liệu Báo cáo Y học: NMR-based determination of the binding epitope and conformational analysis of MUC-1 glycopeptides and peptides bound to the breast cancer-selective monoclonal antibody SM3 pptx

... residue and/ or by the binding contribution from theGalNAcresidue. Docking the glycopeptide to the antibody the sugar ring has little contact to the protein surface. Only the N-acetyl methyl group ... struc- ture into the binding cavity of SM3 and the binding epitope obtained from STD NMR is very good. Comparison with the X-ray and previous NMR structures As men...
Ngày tải lên : 21/02/2014, 15:20
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Tài liệu Báo cáo Y học: Antibacterial and antifungal properties of a-helical, cationic peptides in the venom of scorpions from southern Africa pptx

Tài liệu Báo cáo Y học: Antibacterial and antifungal properties of a-helical, cationic peptides in the venom of scorpions from southern Africa pptx

... parabutoporin and opistoporin The peptides were prepared by solid-phase synthesis by Ansynth Service B.V. (the Netherlands) using the Fmoc/ tert-butyl-based methodology with Rink resin as the solid support. ... same family, independent of the continent and region where they live. In this study, the biological activity of parabutoporin and opistoporin 1 is compared wit...
Ngày tải lên : 21/02/2014, 15:20
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Tài liệu Báo cáo Y học: Antimicrobial dendrimeric peptides pot

Tài liệu Báo cáo Y học: Antimicrobial dendrimeric peptides pot

... quantitatively induced erythrocytes aggregations. Proteolytic stability The proteolytic stability of d endrimeric peptides to trypsin and chymotrypsin was determined using peptide and enzyme in ratio of ... respectively. In contrast, the hemolytic activity of the dendrimeric R4 peptides increased only 2.3 -and3 .3-foldfromR4toD 2 R4 and D 4 R4 peptides, respectivel...
Ngày tải lên : 22/02/2014, 04:20
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Tài liệu Báo cáo Y học: Toxicity of substrate-bound amyloid peptides on vascular smooth muscle cells is enhanced by homocysteine docx

Tài liệu Báo cáo Y học: Toxicity of substrate-bound amyloid peptides on vascular smooth muscle cells is enhanced by homocysteine docx

... (b -site APP cleaving enzyme) at the N-terminus of Ab [4,5] and by an as yet unidentified c-secretase at the C-terminus of Ab (reviewedin[6]).Ab is the main component of vascular amyloid in Alzheimer’s ... a wavelength of 490 nm. Total lactate dehydrogenase was determined by lysing cells in 0.2% Triton X-100 in DMEM/ 10% fetal bovine serum and measuring the total a...
Ngày tải lên : 22/02/2014, 07:20
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Tài liệu Báo cáo Y học: Ligand interactions and protein conformational changes of phosphopyridoxyl-labeled Escherichia coli phosphoenol pyruvate carboxykinase determined by fluorescence spectroscopy pdf

Tài liệu Báo cáo Y học: Ligand interactions and protein conformational changes of phosphopyridoxyl-labeled Escherichia coli phosphoenol pyruvate carboxykinase determined by fluorescence spectroscopy pdf

... points to changes in the dynamical properties of the local environment of the P-pyridoxyl group due to changes of the protein conformation induced by the binding of PEP or the ternary combination. Quenching ... high binding affinity of PEP in the presence of Mn 2+ [28]. The high affinity of PEP in the presence of Mn 2+ suggests a specific interaction...
Ngày tải lên : 21/02/2014, 01:21
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