... occur in the brain includeselective loss of dopaminergic neurons in substantianigra pars compacta and appearance of Lewy bodiesconsisting of aggregated protein, mainly a-synuclein, in Keywordsamyloid; ... results obtained when a-synuclein wasincubated in the absence of MPTP. When a-synucleinwas incubated alone in the presence of dopamine, itled to inhibition of fibrillation, probably by the accu-mulation ... lM neurotoxin (•, dotted line), in thepresence of 200 lM neurotoxin ( , dottedline) and in the presence of neurotoxin and50 lM dopamine (h, dashed line).Modulation of a-synuclein aggregation...