... immune and endocrine systems, components of signaling pathways and of the ubiquitin–proteasomepathway, and genes of tumor viruses. Activation of cell-cycle regulators, proto-oncogenes and genesinvolved ... not transactivated byFOXM1c(189–762) (Fig. 1C).The P1 and P2 TATA boxes are theFOXM1c-responsive elementsThe existence of FOXM1c-responsive and -nonrespon-sive minimal promoters offered the ... transactivation; IA, interaction; P1, P2, P1- or P2-promoter of c-myc. (E, F)TAD, transactivation domain; DBD, DNA-binding domain; TRD, transrepression domain; EDA, essential domain for activation;...