... NSW 2109, Australia
Abstract
Many semantic parsing models use tree trans-
formations to map between natural language
and meaning representation. However, while
tree transformations are central to ... transformation based mapping, and (c) a tree trans-
ducer that performs the mapping.
volve tree transformations either between two trees
or a tree and a string.
The tree transducer,...
... enzymes
show an important variation. Usually there is another
H residue, but in some cases an L residue is found
(for instance, in the NP_519622 protein from R. solana-
cearum and in all animal tyrosinase-related ... with an abnormally high tyrosine
hydroxylase/dopa oxidase ratio
Role of the seventh histidine and accessibility to the active site
Diana Herna
´
ndez-Romero
1
, Antonio S...
... We
also thank the staff members at beamline ID14-1 for
their skilled assistance, and B. Hillebrant-Chellaoui at
VTT for skilful help with the TaLcc1 purification.
Roal Oy and the Academy of Finland ... solution with
four molecules in an asymmetric unit, with a Matthews
coefficient probability of 2.61 A
3
ÆDa
)1
and a solvent
content of 52.9%. Interestingly, molecules A and B
(and C and...
... mu, mu ta, Ve nhirng ttr
danh gii hoac mieu ti binh vi, cd: ngu, tdi,
meng, chang ra ehd gi, chang nudc me gi,
an thua gi, an thua me gi, nudc non gi, an
vang an bac gi, biet tay, phii Idng, ... each chiire nang.
Ve mat ngudn gog, thi phin nhieu li cic tur
gde Hin va gde An Au dupc du nhap.
2.
Van hanh chinh (van phong phip ly;
hanh chfnh - cdng vu ) ddi hdi viet van
ban th...
... HIV-1 protease and its
drug-resistant mutants altering hydrophobic clusters
Chen-Hsiang Shen
1
, Yuan-Fang Wang
1
, Andrey Y. Kovalevsky
1,
*, Robert W. Harrison
1,2
and
Irene T. Weber
1,3
1 Department ... resistance and help in the design of
new inhibitors.
Results
APV inhibition of PR and mutants
The kinetic parameters and inhibition constants of APV
for PR
WT
and the drug-resistant mutants...
... performed by calculating the Ramachandran
plot with the program sirius (San Diego Supercomputer
Center, San Diego, CA, USA).
Metal analysis
This was performed with an inductively coupled plasma
optical ... 000 g), and subsequently analyzed by HPLC
using a Merck-Hitachi La Chrom system (Darmstadt,
Germany) equipped with an Aminex HPX-87H column
(Biorad, Hercules, CA, USA) as well as...
... has been corroborated by kinetic and structural
analysis of different LpPOX variants (G. Wille and
K. Tittmann, unpublished results).
Kinetic and spectroscopic analysis of
oxidation–reduction ... active site and the long distance between the two
cofactors ($ 11 A
˚
between ThDP-C2 and FAD-N5 or
FAD-C4a) relegate a direct carbanion mechanism with
covalent HEThDP-FAD linkage or an alternati...
... primary structures and known protein
domains (colored boxes) for selected vaccine candidates and lead vaccines. Cleavable signal peptides and transmembrane spans are boxed
in red and black, respectively. ... parasites
and transmission-blocking antigens, induce immune responses superior to
naturally acquired immunity. The promises and hurdles of the different
tracks towards an effective and...
... several LolC
and LolE mutants that suppress dominant negative
mutants of LolD [14]. Interestingly, the suppressor
mutations of LolE were mostly located in the cytoplas-
mic and transmembrane regions, ... membrane
subunit and LolD (molecular mass ¼ 138–142 kDa),
although an ABC transporter is generally composed of
two membrane domains and two nucleotide-binding
domains.
Discussion
Bacterial...
... ⁄ PAGE, trans-
ferred onto nitrocellulose and blotted with phosphotyrosine (4G10)
antibodies. The upper half of the membrane was reprobed with
anti-PDGFR IgG and the lower part with anti-EE IgG. ... days
postinfection and S6Ks were immunoprecipitated with anti-EE IgG. Samples were resolved by SDS ⁄ PAGE, transferred onto nitrocellulose
membrane and analyzed by immunoblotting with mo...