Tài liệu Báo cáo khoa học: "k-valued Non-Associative Lambek Categorial Grammars are not Learnable from Strings" pptx

... L∅ grammars (with-out product) with types not greater than or-der 5 are not learnable from strings4.- k-valued free pregroup grammars with type-s not greater than order 1 are not learnable from ... and Remarks Lambek grammars. We have shown that with-out empty sequence, non-associative Lambek rigid grammars are not learnable from strings. With thisresult, the whole landscape of Lambek- like ... concerned with learning cat-egorial grammars in Gold’s model. Incontrast to k-valued classical categorial grammars, k-valued Lambek grammars are not learnable from strings. This re-sult was shown...

Tài liệu Báo cáo khoa học: Seeking the determinants of the elusive functions of Sco proteins pptx

... are shown. Cysteine residues involved in copper binding or disulﬁde bond formation are shown as yellow sticks.Histidine Cu(I) ligands in Sco1 and Sco2 are shown as blue sticks. Copper ions are ... bioin-formatics analysis of 311 prokaryotic genomes (285 from Bacteria and 26 from Archaea) revealed that Scoproteins are present in a large variety of species from both Bacteria and Archaea, which in most ... SenC) from thepurple photosynthetic bacterium Rhodobacter capsula-tus, which does not have a CuA-containing COX [84].A role for Sco proteins in cbb3oxidase assembly couldin part, but not...

Tài liệu Báo cáo khoa học: Hypothalamic malonyl-CoA and CPT1c in the treatment of obesity pptx

... nervous system–metabolism axis are still lacking.Metabolic sensingEndocrine signals from the pancreas, adipose tissueand gastrointestinal tract, as well as other sites, are known to reach the CNS ... tissues to affect energy intake and expendi-ture. It has become apparent that certain regions ofthe brain, notably the hypothalamus, are also respon-sive to circulating nutrients that reﬂect the ... however, it does not perform the samebiochemical function as the prototypical CPT1 enzymes. Mouse knockoutmodels of CPT1c exhibit suppressed food intake and smaller body weight,but are highly susceptible...

Tài liệu Báo cáo khoa học: Mixed lineage leukemia: histone H3 lysine 4 methyltransferases from yeast to human pptx

... Grant (0635008N) from American Heart Association, a Research ScholarGrant (06-52) from American Cancer Society, aMallinckrodt Foundation award, and several internalgrants from Southern Illinois ... CGBPaDPY-30HCF1aWdr82 and CFP1 ⁄ CGBP are present in human SET1A and SET1B complexes, but not in mouse [117,165,166].H3K4 methyltransferases from yeast to human S. Malik and S. R. Bhaumik1808 ... factor)in S. cerevisae COMPASS is not found in Sch. pombe[70–72]. Together, these observations support the factthat the Set1 HMTs from S. cerevisae and Sch. pombe are highly conserved (Tables 1–3),...

Tài liệu Báo cáo khoa học: Structural features of proinsulin C-peptide oligomeric and amyloid states pptx

... ofMg2+appeared to reduce the formation of larger olig-omeric species (15–30 kDa), whereas a strong bandcorresponding to peptide dimers is apparent. Low con-centrations of Mg2+did not affect ... open square, buffer; grey solid circle, 0.5 mM SDS; grey opentriangle, 1 mM SDS; black solid star, 1.5 mM SDS; grey open circle,2mM SDS; grey solid square, 3 mM SDS; grey open square, 6 mMSDS; ... lipid vesi-cle bilayers do not result in any membrane-inducedstructure conversion in C-peptide, which indicates thatphysiological effects of C-peptide are most likely not mediated by direct membrane...

Tài liệu Báo cáo khoa học: A novel electron transport system for thermostable CYP175A1 from Thermus thermophilus HB27 doc

... sequences of FNR from T. thermophilus HB27, TR from E. coli, and TR from A. pernix.Accession numbers (NCBI) are: FNR from T. thermophilus HB27, YP_004071; TR from E. coli, NP_415408; and TR from A. pernix,NP_147693. ... reductase from Saccharomyces cerevisiae, AAB64812; FprA from Mycobacterium tuberculosis, O05783; BphA4 from Pseudomonas sp. KKS102, BAA04112; putidaredoxin reductase from P. putida,AAA25758; FNR from ... 7120, NP_488161;FNR from Zea mays, NP_001105568; FNR from E. coli, NP_418359); FNR from Azotobacter vinelandii, ZP_00417949; FNR from Rhodobact-er capsulatus, AAF35905; ADR from Homo sapiens,...

Tài liệu Báo cáo khoa học: Toggle switches, pulses and oscillations are intrinsic properties of the Src activation/deactivation cycle doc

... in thebypass from Sa1to Si(Fig. 1). In Fig. S4A, B, it isshown that both Src oscillatory patterns and bistability are observed when step 7 is saturable, whereas step 4is not. However, ... points, aliquots are taken,and the different phosphotyrosine levels that corre-spond to different Src conformations are measured byimmunoblotting using specific antibodies (note thatquantification ... Src will be deacti-vated by inhibitory Csk phosphorylation already in theareas that are only at a small distance from the localstimuli [51]. Our findings suggest that Src travelingwaves can...

Tài liệu Báo cáo khoa học: Structural and mechanistic aspects of ﬂavoproteins: probes of hydrogen tunnelling pptx

... sar-cosine oxidase; nd, not determined or reported. The KIEs are for pre-steady-state ﬂavin reduction by the denoted substrate unless otherwisestated. Isotope effects are H ⁄ D unless otherwise ... [17]aRevised from previously reported, manuscript in preparation.bData from kcat⁄ Kmmeasurements.cData not corrected for the calculatedcommitment to catalysis.dData from H ⁄ T isotope ... of the enzymes used in these syntheses(excluding MR) are available from Sigma-Aldrich (St.Louis, MO, USA) and the coenzymes are available from Melford Laboratories (Chelsworth, UK). We useextinction...

Tài liệu Báo cáo khoa học: Regulators of G-protein signalling are modulated by bacterial lipopeptides and lipopolysaccharide pptx

... similar data were obtained in three independent experiments. Data for ELISA are the mean ± SE from two experiments.RGS are modulated by lipopeptides and LPS S. Riekenberg et al.652 FEBS Journal ... factors likeNf-jB are activated and the induction of proinﬂamma-tory cytokines are found [38]. The participation of thesesignal transduction molecules in RGS1 and RGS2modulation is not obvious, ... obtained from Invitrogen (Karlsruhe,Germany). Fetal calf serum (Linaris, Wertheim-Bettingen,Germany) was heat-inactivated before use. LPS from Salmonella enterica serovar Friedenau was a gift from H....

Tài liệu Báo cáo khoa học: Cosubstrate-induced dynamics of D-3-hydroxybutyrate dehydrogenase from Pseudomonas putida ppt

... tensor are listed andthe mean value shown in brackets.This material is available as part of the online article from http://www.blackwell-synergy.comPlease note: Blackwell Publishing is not responsiblefor ... the total B factor and its contribution from the rigid body movements (BTLS, obtained from arefinement of translation, libration and screw tensors)and from the individual atom or residue movement(Bresidual).Table ... present the structurerefined from crystals obtained in the presence of aceto-acetate because the best data were obtained from thesecrystals. Many crystals of PpHBDH suffered from a sig-nificant orientational...

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