Tài liệu Báo cáo khoa học: "The Second Release of the RASP System" pdf
Tài liệu Báo cáo khoa học: An autoinhibitory effect of the homothorax domain of Meis2 ppt
... presence of alternative splicingaround the 5¢-end of exon 6 of Meis2 and Meis3 was tested by RT-PCR. The positions of molecular mass markers are shown to the left,and the size in base pairs of the ... However, the activity of the full-length Meis1awas not tested, and on the basis of our work we expectthat its activity would be inhibited by the conservedHth domain. The Meis1a isoform, in which the C-terminal ... independently of Pbx, and does notpossess the autoinhibitory function of the Hth domain.In summary, our data suggest that one function of the conserved Hth domain is to inhibit the activity of the transcriptional...
- 14
- 753
- 0
Tài liệu Báo cáo khoa học: Investigation and prediction of the severity of p53 mutants using parameters from structural calculations pptx
... R175H)[9]. A second advantage of p53 mutation analysis,and a unique feature of this database, is the availabil-ity of the residual activity of the majority of p53 mis-sense mutants. The biological ... algorithms have been developed recently [4–7]. The major drawback of these analyses is the lack of information regarding the activity or loss of activity of the target protein, as only a few variants ... buried inside the protein when a spherewith the size of a water molecule van der Waals’ radius is rolled over the protein surfaceSimilarity of the surroundings* Measure of the percentage of amino...
- 14
- 561
- 0
Tài liệu Báo cáo khoa học: Substrate specificity of the pseudouridine synthase RluD in Escherichia coli doc
... obtained with the transition at posi-tions 1915 and 1917. These mutations had an effect on the formation of pseudouridine exclusively at the mutant position and did not affect either of the othertwo ... bySouthern analysis. The rluD::cat strain had a full deletion of both rluD and yfiH, together with their annotated pro-moter sequences. The inserted cat cassette had a distance of 90 nt from the ... at which stage of the complex maturationprocess does the modification of a given nucleosideoccur and (b) how does the corresponding enzyme rec-ognize the target site within the tRNA architecture[20]?...
- 8
- 596
- 0
Tài liệu Báo cáo khoa học: Receptor binding characteristics of the endocrine disruptor bisphenol A for the human nuclear estrogen-related receptor c pptx
... Given that the roles of these residues definitely confirm each other, the dif-ference in their significance might be attributable to the importance and ⁄ or necessity of the receipt of the phenol-hydroxyl ... environments of BPA in the ligand-binding pocket of the ERRc. The proximity of each amino acid residue (within adistance of 5 A˚) to BPA is shown in the boxes depicting the a -heli-ces. The portrait ... for the major role of Arg316 in arresting the ligandWhen the amino acid sequences of the LBD of all the NRs were aligned to that of ERRc, it became notice-able that 26 receptors among the total...
- 12
- 583
- 0
Tài liệu Báo cáo khoa học: N-terminal extension of the yeast IA3 aspartic proteinase inhibitor relaxes the strict intrinsic selectivity ppt
... each extremity of the polypeptidechain, must of necessity arise from contacts that aremade outwith the active site of the enzyme. The effect of removal of the N-terminal extension The full N-terminal ... binding of this helical N-terminal seg-ment of IA3. The E + I « EI balance thus lies far to the right and the addition of further residues at the N-terminus or beyond residue 34 of the inhibitorysegment ... residues69–81 from the S. castellii sequence is small comparedto that achieved by location of the full-length extensionat the N-terminal end of the polypeptide. The benefit of these alterations...
- 10
- 510
- 0
Tài liệu Báo cáo khoa học: Salt-induced formation of the A-state of ferricytochrome c – effect of the anion charge on protein structure docx
... less sensitive to the pres-ence of the anion. These residues also modulate the conformation of unfol-ded cytochrome c, influencing its spin state and the coordination to the prosthetic group.AbbreviationCT, ... effect of Cl–reflects the different affinities of the two anionsfor the protein [11,17].We also monitored the effect of sulfate on the perchlorate-induced A-state. As shown in Fig. 6, addi-tion of ... that the variants undergo very fast optical (and thus structural)changes within the dead time of the stopped-flowapparatus. In the case of the K13N mutant, this hypo-thesis finds support from the...
- 11
- 487
- 0
Tài liệu Báo cáo khoa học: Co-operative effect of the isoforms of type III antifreeze protein expressed in Notched-fin eelpout, Zoarces elongatus Kner ppt
... on, the addition of a smallamount of a QAE1 isoform, nfeAFP8 (Fig. 7). This issimilar to the case of the QAE2 isoform, nfeAFP13; the activity of its monomer was enhanced by the pres-ence of ... sequence alignment of nfeAFPs The complete amino acid sequences of the 13 isoforms of nfeAFP were determined based on the cDNAABFig. 2. (A) HPLC purification of the isoforms of type III AFP from ... samples 11–14 correspond to QAE isoforms of nfeAFP, whereas the others correspond to SP iso-forms, and the TH activity of the QAE isoform ishigher than that of the SP isoform.Fig. 6. TH activity...
- 11
- 696
- 0
Tài liệu Báo cáo khoa học: A kinetic model of the branch-point between the methionine and threonine biosynthesis pathways in Arabidopsis thaliana doc
... interms of the number of the enzymes involved, the kineticmechanisms of the competing enzymes and the number aswell as the nature of the allosteric controls. Whether suchdiversity in the organization ... changes in the concentration of Pido notmodify the partition (Fig. 3A). However, the presence of Piconsiderably affects the dynamics of the system. Indeed, in the presence of 10 mMPi, the model ... was of special interest to use the in vitro system to test the effect of AMP on the partition of the flux of Phser underphysiological conditions. The partition was measured in the conditions of...
- 13
- 906
- 0
Tài liệu Báo cáo khoa học: "On Learning Subtypes of the Part-Whole Relation: Do Not Mix your Seeds" pdf
... were discarded. The precision of the tuples discovered by the different seed-sets in the last iteration of our algorithm are in Table 3.These results reveal that the precision of har-vested ... comparing the results of these three sets among themselves, andwith the results of the member -of and contained-in seeds, indicating insignificant similarity andoverlap. Examining the patterns ... similarity.In Proceedings of the Joint Conference of the 47thAnnual Meeting of the ACL and the 4th InternationalJoint Confe rence on Natural Language Processing of the AFNLP, pages 396–404.G.A....
- 9
- 622
- 0
Tài liệu Báo cáo khoa học: "A COMPUTATIONAL VIEW OF THE COGNITIVE SEMANTICS OF SPATIAL PREPOSITIONS*" ppt
... Here the x-axis points direction of the half- axis of the particular side of the reference axis in the DCS; and in the case of "in front of& quot; y is the perpendicular direction in the ... addition to the constraint on the proximity of the LO and RO, projective prepositions place a constraint on the position of the LO relative to a particular side of the RO. In the case of the intrinsic ... of the long desk is a chair. Another chair is to the left of the long desk. The chair in front of the desk is near the short desk." OTHER APPROACHES AND CLOSING REMARKS Nearly all the...
- 7
- 552
- 1
Từ khóa: Nghiên cứu sự biến đổi một số cytokin ở bệnh nhân xơ cứng bì hệ thốngNghiên cứu tổ chức pha chế, đánh giá chất lượng thuốc tiêm truyền trong điều kiện dã ngoạiGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitĐỒ ÁN NGHIÊN CỨU CÔNG NGHỆ KẾT NỐI VÔ TUYẾN CỰ LY XA, CÔNG SUẤT THẤP LPWANĐỒ ÁN NGHIÊN CỨU CÔNG NGHỆ KẾT NỐI VÔ TUYẾN CỰ LY XA, CÔNG SUẤT THẤP LPWANQuản lý hoạt động học tập của học sinh theo hướng phát triển kỹ năng học tập hợp tác tại các trường phổ thông dân tộc bán trú huyện ba chẽ, tỉnh quảng ninhPhối hợp giữa phòng văn hóa và thông tin với phòng giáo dục và đào tạo trong việc tuyên truyền, giáo dục, vận động xây dựng nông thôn mới huyện thanh thủy, tỉnh phú thọTrả hồ sơ điều tra bổ sung đối với các tội xâm phạm sở hữu có tính chất chiếm đoạt theo pháp luật Tố tụng hình sự Việt Nam từ thực tiễn thành phố Hồ Chí Minh (Luận văn thạc sĩ)Định tội danh từ thực tiễn huyện Cần Giuộc, tỉnh Long An (Luận văn thạc sĩ)Sở hữu ruộng đất và kinh tế nông nghiệp châu ôn (lạng sơn) nửa đầu thế kỷ XIXChuong 2 nhận dạng rui roGiáo án Sinh học 11 bài 15: Tiêu hóa ở động vậtGiáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtGiáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtGiáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtGiáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtBÀI HOÀN CHỈNH TỔNG QUAN VỀ MẠNG XÃ HỘIHIỆU QUẢ CỦA MÔ HÌNH XỬ LÝ BÙN HOẠT TÍNH BẰNG KIỀMMÔN TRUYỀN THÔNG MARKETING TÍCH HỢP