... results demonstrate an impor-tant relationship among the regulation of nucleo-lin ⁄ C23, the activation of caspase-3 and the induction of apoptosis under the setting of oxidative stress and Hsp70 ... stressBimei Jiang1, Bin Zhang1, Pengfei Liang2, Juan Song1, Hongbing Deng1, Zizhi Tu1, Gonghua Deng1 and Xianzhong Xiao11 Department of Pathophysiology, Xiangya School of Medicine, ... condensation and DNAfragmentation [1,2], apoptosis can cause irreversibleloss of terminally differentiated cardiac myocytes and, therefore, contributes significantly to the pathogenesis of many...