Tài liệu Báo cáo khoa học: "The Impact of Query Reﬁnement in the Web People Search Task" docx

Tài liệu Báo cáo khoa học: Molecular defect of isovaleryl-CoA dehydrogenase in the skunk mutant of silkworm, Bombyx mori ppt

... strainsrevealed the presence of a single point mutation in 1337 nucleotides of BmIVD. In the sku mutant, the 1127th guanine from the start codon was substitutedby thymine and none of the other sites ... acts in the third step of leucine degradation and the sku mutant accumulates branched-chain amino acids in haemolymph, thismutant may be useful in the investigation of unique branched-chain aminoacid ... [7]. The model of wild-typeBmIVD indicated that all the side chains in the loopconnecting helices I and J are exposed on the surface of the monomer, pointing toward FAD or its neigh-bouring...

Tài liệu Báo cáo khoa học: Molecular aspects of rheumatoid arthritis: chemokines in the joints of patients pdf

... chemokines stimu-lated mainly by in ammatory cytokines, including IL-1b, TNF-a andIFN-c. (B) Chemokines expressed in the joint recruit leukocytes into the joints. In addition to functioning in ... aG-protein that transduces the intracellular signal. The two major subclasses include the CC chemokines(where the cysteines are neighboring) and the CXCchemokines (where the cysteines are ... polyarticular joint dis-ease that primarily affects the small joints of the hands and feet. The in ammatory process is characterized by in ltration of in ammatory cellsinto the joints, leading to proliferation...

Tài liệu Báo cáo khoa học: Electrostatic role of aromatic ring stacking in the pH-sensitive modulation of a chymotrypsin-type serine protease, Achromobacter protease I pdf

... position. In the struc-tural deviation, the solvent ASA of the side-chain of His210increased with the decrease in size of the side-chain atresidue 169 (Table 1 and Fig. 3A). However, the ASAs of Asp113 ... size of the side-chain at residue 169 and the pK2showed a clear linear relationship (Fig. 3B). The pK2increased as the size of the residue at position 169 increased. The effect of the size of ... thisprotease at pH9 [10]. Further interest in the aromaticstacking is in the role of the electrostatic properties in enzymatic catalysis of API, and in distinguishing the functionally catalytic quadruple...

Tài liệu Báo cáo khoa học: "The Impact of Query Reﬁnement in the Web People Search Task" docx

... actual impact of us-ing query refinements in the Web People Search (WePS) clustering task (as defined in the frame-work of the WePS evaluation). For this, we havestudied to what extent a query refinement ... Proceedings of the ACL-IJCNLP 2009 Conference Short Papers, pages 361–364,Suntec, Singapore, 4 August 2009.c2009 ACL and AFNLP The Impact of Query Refinement in the Web People Search TaskJavier ... only according to their cv, but also ac-cording to their web profile, i.e. information aboutthem available in the Web. One question that naturally arises is whether search results clustering can...

Tài liệu Báo cáo khóa học: Point mutations associated with insecticide resistance in the Drosophila cytochrome P450 Cyp6a2 enable DDT metabolism doc

... respectively. Thesevariations of the ratios of the metabolites suggest modiﬁ-cations in the catalytic mechanism responsible for the metabolism of DDT.Substrate binding The substrate induced binding ... mutatedpositions in CYP6A2 (helix J and vicinity of the b sheet 3–3).These results are also original because this is the ﬁrstdescription of the role of mutations in the metabolism of aninsecticide ... resistance in the RDDTRstrain of Drosophila melanogaster. To determine the impact of each mutation on the function of CYP6A2, the wild-typeenzyme (CYP6A2wt) of Cyp6a2 was expressed in Escheri-chia...

Tài liệu Báo cáo khoa học: An immunomodulator used to protect young in the pouch of the Tammar wallaby, Macropus eugenii pptx

... production of inter-leukins and secretion of immunoglobulins on the mucosal surface of the intestine [49,50]. The antibacte-rial defence of the intestinal mucosa depends in parton stimulation of CCK ... euge-nin, indicating that eugenin is indeed acting throughCCK2receptors.To further investigate the interaction of eugenin withCCK2receptors, we investigated the effect of eugeninon lymphocyte ... fractioncontaining eugenin is indicated by an asterisk in Fig. 2.Two further HPLC separations of the initial eugenin frac-tion (10–75% acetonitrile over a period of 60 min at a ﬂowrate of 1 mLÆmin)1.)...

Tài liệu Báo cáo khoa học: "Using adaptor grammars to identify synergies in the unsupervised acquisition of linguistic structure" docx

... terminal in the grammar. If Ais a terminal then GAis the distribution that puts all of its mass on the unit tree (i.e., tree consisting of asingle node) labeled A. If A is a nonterminal thenGAis ... parse of thatstring with a PCFG approximation to the adaptorgrammar. This PCFG contains a production for eachadapted subtree in the parses of the other strings in the training corpus. A ﬁnal ... it gives us a way of learning theseinteracting linguistic structures simultaneously.Adaptor grammars are also interesting becausethey can be viewed as directly inferring linguisticstructure....

Tài liệu Báo cáo khoa học: Molecular determinants of ligand speciﬁcity in family 11 carbohydrate binding modules – an NMR, X-ray crystallography and computational chemistry approach doc

... to gainfurther insight into the binding mode of different carbohydrates (cellobiose,cellotetraose and cellohexaose) to the binding pocket of the family 11CBM. The crystal structure of C. thermocellum ... 6). The interaction leads to a slightalteration of the normal chain dihedral angles of the Table 1. Summary of the distances involved in the main interactions between the carbohydrates and the ... 1III–V), which could indicate that the corre-sponding hydroxyl groups are involved in proteinbinding. The results for the linebroadening measurements of protons H1a in the alpha and beta conﬁgurations,aHa1...

Tài liệu Báo cáo khoa học: Transient silencing of Plasmodium falciparum bifunctional glucose-6-phosphate dehydrogenase) 6-phosphogluconolactonase docx

... because of the import-ance of this enzyme in the parasite’s intraerythrocytestage [16]. The present paper describes the effects of G6PD-6PGL silencing in P. falciparum, conﬁrming the key role of ... nevertheless experimentally shown that this62 amino acid insertion is essential for the activity of the bifunctional enzyme [16]. In contrast, the 310amino acid protein sequence of the N-terminal ... effect of using this vector. This is the ﬁrstreport of the detection at the molecular level of the toxic effect of a DNA vector in P. falciparum.Although mechanisms of RNAi silencing in manyspecies...

Tài liệu Báo cáo khoa học: "Some Uses of Higher-Order Logic in Computational Linguistics" pdf

... Networks" in Artificial Intelligence 13 (1980). [11] David Scott Warren, "Using A-Calculus to Represent Meaning in Logic Grammars" in the Proceedings of the 21st Annual Meeting of the ... Consideration of the question of meaning in the frame- work of linguistics often requires an allusion to sets and other higher-order notions. The traditional approach to representing and reasoning about ... assume that the following symbols, called the log- ical constants, are included in the set of constants of the corresponding type: true of type o, ~ of type o * o, A, V, and D each of type o...

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