... observable.Interestingly, the RMI1 mRNA level increased signifi-cantly in the liver and intra-abdominal fat of the obesephenotype mice; however, that in the skeletal muscledid not increase, and that in ... high-fatdiet contains 32% safflower oil, 33.1% casein, 17.6%sucrose, 1.4% vitamin mixture, 9.8% mineral mixture, 5.6%cellulose powder and 0.5% dl-methionine. Casein, sucroseand the vitamin and mineral ... theBloom’s syndrome gene helicase complex that maintains genome integrityand activates cell-cycle checkpoint machinery. Interestingly, diet-inducedexpression of E2F8 mRNA, which is an important...