... family kinases in health and disease – loss -of- function of BTK and ITK and the gain -of- function fusions ITK–SYKand BTK–SYKAlamdar Hussain1,2,*, Liang Yu1,3,*, Rani Faryal1,2, Dara K. ... transcriptome of both human [35] and mouse[51,53] CD8+cells, which express very high levels of the transcription factor eomesodermin, whose owntranscription is suppressed by ITK [35,51]. Anotherimportant ... COMSATS Institute of Information Technology, Islamabad, Pakistan3 Department of Hematology, Huaian No. 1 Hospital, Nanjing Medical University, Huaian, Jiangsu, China4 Faculty of Science (Biology),...