Tài liệu Báo cáo khoa học: Stem–loop oligonucleotides as tools for labelling double-stranded DNA pdf

... 771–777. Stem–loop padlock oligonucleotides for dsDNA B. Ge´ron-Landre et al.5352 FEBS Journal 272 (2005) 5343–5352 ª 2005 FEBS Stem–loop oligonucleotides as tools for labelling double-stranded DNA Beńe´dicte ... ParisTriple-helix forming oligonucleotides (TFOs) repre-sent an interesting tool for the sequence-specificrecognition of double-stranded DNA. They can beused for the artificial modulation of DNA informa-tion ... processing [1] and for other applications thattake place in vitro, such as double-stranded DNA isolation, labelling or modification (reviewed in [2]).Formation of DNA triple helices has been studied...

Tài liệu Báo cáo khoa học: "Nonlinear Evidence Fusion and Propagation for Hyponymy Relation Mining" pdf

... respectively. It is easy to prove (by following a similar procedure) that the above Formula holds for the case of m>2, as long as the pieces of evidence are mutually independent. Therefore for a term-label ... the Association for Computational Linguistics, pages 1159–1168,Portland, Oregon, June 19-24, 2011.c2011 Association for Computational LinguisticsNonlinear Evidence Fusion and Propagation for ... Meet-ing of the Association for Computational Linguistics (COLING-ACL-06), 801–808. P. P. Talukdar and F. Pereira. 2010. Experiments in Graph-based Semi-Supervised Learning Methods for Class-Instance...

Tài liệu Báo cáo khoa học: "An Improved Redundancy Elimination Algorithm for Underspeciﬁed Representations" pdf

... 13log(#configurations)FactorAlgorithm Baseline ClassesFigure 5: Mean reduction factor on Rondane.equivalence classes with respect to RERG; for effi-ciency reasons we could only compute this num-ber for USRs with ... of the graph, as alower bound for any algorithm that computes theequivalence classes based on the full set of config-urations. Fig. 7 shows the mean runtimes for eachlog(N) class, on the USRs ... of ex-istential quantifiers. These rules approximate clas-sical semantic equivalence of first-order logic, as they rewrite formulas into classically equivalentones. Indeed, all five configurations...

Tài liệu Báo cáo khoa học: Activation loop 3 and the 170 loop interact in the active conformation of coagulation factor VIIa pdf

... is required for the mem-brane-associated procoagulant activity that triggers theclotting cascade [1,2]. Importantly, formation of thebinary complex localizes FVIIa to the site of vasculardamage, ... Kivalue for inhibition by p-aminobenzami-dine (PABA) was seven-fold higher for G372A-FVIIain complex with sTF than for sTF-bound FVIIa (0.70versus 0.10 mm)(Fig. 2).The kinetics of sTF binding as ... (FVIIa-PEG2k) was plotted as a function of time, a similarprotective effect of sTF was observed for G372A-FVIIa and FVIIa (Fig. 4B). The apparent difference inthe rate of pegylation of the free forms...

Tài liệu Báo cáo khoa học: Angiopoietin-like proteins: emerging targets for treatment of obesity and related metabolic diseases pptx

... with increased risk of cardiovascular disease, the leading cause ofdeath. Therefore, it is important to understand the molecular basis underly-ing obesity and related metabolic diseases in order ... signaling has few sideeffects. Therefore, for these reasons, we consider thatthe suppression of ANGPTL2 signaling as a therapeu-tic strategy is more beneﬁcial.Because ANGPTL2 promotes vascular ... sideeffects, such as increased body weight (adiposityand ⁄ or edema), altered bone metabolism and undesir-able long-term cardiovascular outcomes (Rosiglitaz-one). For these reasons, the recently...

Tài liệu Báo cáo khoa học: Proteolytic processing regulates pathological accumulation in dentatorubral-pallidoluysian atrophy pdf

... the cytoplasm and assembles inthe cytoplasmic organelle. Caspases aredirectly involved in the cleavage of F2, andregulate the accumulation of F2 in the cyto-plasm. (B) When caspase activity ... have determinedthat caspase acts as a catabolic enzyme that targetsproteins with a polyQ tract. For example, Wellingtonet al. [20] predicted that cleavage sites for caspase werecontained in ... and fragments increased in the COS-7 cells as the size of the polyQ was increased.Next, we assessed whether the quantitative increaseof the full-length ATN1 and fragments was the resultof an...

Tài liệu Báo cáo khoa học: An allosteric DNAzyme with dual RNA-cleaving and DNA-cleaving activities doc

... and RNaseH were purchased from MBI. All chemical reagents werepurchased from BBI.Activity assays for the DNAzymeTo assess the cleavage activity of the DNAzyme, radiola-beled RNA or DNA were ... vitro-selected pistol-like (PL) DNAzyme as a DNA scaffold for designing a DNAzyme with dual catalytic activities. Weprepared the 46-nucleotide DNAzyme with DNA- cleaving activity(PL DNAzyme), and then grafted ... RNA-cleaving activity of DRc DNAzyme was assayed atABCDFig. 2. The DNA- cleaving activity and cleavage sites of DRc DNAzyme. (A) 5¢-32P-labeled DRc DNAzyme was incubated in buffer A at 23...

Tài liệu Báo cáo khoa học : Chủ nghĩa xã hội đặc sắc ở Trung Quốc pdf

... (1996) neu ro : Tang cUdng xay dflng dao dflc tU tfldng, phit trien giio due khoa hpc van hoi, dung ly luan khoa hgc de vu trang cho con ngUdi, diing da luan dung ddn de hUdng ddn con ngUdi, ... noi dung chu yeu cua CNXH dac sic Trung Qud'c, sau dd neu len mot so' nhan x6t. TUkhoa: Trung Qud'c, CNXH, XNXH dac sic Trung Qud'c PGS. TS D6 TI^'N SAM Vien ... nhflng nguyen Iy cd ban cua Chu nghia Mic vdi thflc te cu the cua Trung Quo'c. Theo cic nha khoa hpc Trung Quo'c, day Id "thanh qua ly luan va thflc tiin to Idn, quan trpng...

Tài liệu Báo cáo khoa học : Bản chất của khủng hoảng kinh tế thế giới pdf

... thd'ng TBCN. 52 Nghien ciiu Kinh teso 370 - Thang 3/2009 Ban chat cua cuoc khung khoang Theo J. Case, uy vien Uy ban Kinh te. Dang Cong san Anh, phan tich cudc KH tren quan diem duy ... chinh cua iMy Dau cd chflng khoan la cd sd ciia sfl khdng on dinh ciia thi trfldng. Nghien ciiu Kinh t4s6 370 ' Thang 3/2009 53 Ban chat cua cuoc khung khoang - Sfl khdng can ... Nghien cuv Kinh teso 370 - Thang 3/2009 Ban chat cua cuoc khung khoang Thang 10-2008 dai dien cac nUdc dang phat trien hop d Caracas, thii do Venezuela, da quyet nghi nhu sau: 1. KH kinh te...

Tài liệu Báo cáo khoa học: A novel electron transport system for thermostable CYP175A1 from Thermus thermophilus HB27 doc

... (reverse primer). PCR was carriedout at 94 °C for 5 min, and this was followed by 30 cyclesof 94 °C for 30 s, 55 °C for 30 s, and 68 °C for 1 min,using KOD Plus DNA polymerase. After the PCR producthad ... purified proteinwas analyzed by MALDI-TOF-MS. Peptide mass fin-gerprinting was used to search the NCBInr databaseusing mascot. The result of the mascot searchsuggested that the band was a protein ... P450and has great potential for industrial applications. However, a native elec-tron transport system for CYP175A1 has not been identified. Here, an elec-tron transport system for CYP175A1 was isolated...

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