... bc1sub-complex, but the presence of only one of these two subunits does not substitutefor the other. After the addition of ISP, the binding of the last subunit (i.e. Qcr10p) finally occurs. These find-ings ... [12,29,32,41]. Of course, the possibility that other protein components of the respi-ratory chain, such as subunits of the cytochrome coxidase, or of the TIM23 machinery, or even of the metabolite ... alsounknown. Furthermore, as in the case of the biogene-sis of other multi-subunit complexes of the mitochon-drial respiratory chain, the assistance of specificchaperone proteins is also required. The...