... belonging t o class I of the superfamily of
bacterial, fungal, and plant heme peroxidases. In Fig. 5 the
simplified inferred
FITCH
tree, is presented, and in Fig. 6
the same tree in a simplified ... feature in this region. The
iron of the prosthetic heme group is invariantly
co-ordinated by the a bove essential proximal h istidine
(Fig. 4A,C,D). Howeve...
... A.
Clade Strain
Antimycin A concentration (l
M)
Rich
medium:
5
Synthetic
minimal
medium:
0.5–25
Synthetic
minimal
medium
plus lysine and
glutamic acid:
0.5–25
Synthetic
minimal
medium
plus
acetoin:
0.5–25
Saccharomyces ... on synthetic minimal
Table 2. (Continued).
Clade Strain
Antimycin A concentration (l
M)
Rich
medium:
5
Synthetic
minimal
medium:
0.5–25
Synthetic
minimal
medium
plus lysi...
... moiety of the catalytic domain, but still containing its core
part (Lys321–Thr620) was inactive in yeast, and was
expressed in E. coli as an inactive polypeptide in the form
of inclusion bodies ... or with the trypanosomal TbPDE2 family.
Outside of the catalytic domain, sequence similarity decrea-
ses, within 10–40 amino acids at the N-terminal side of the
domain,...
... using
the main chain of residues Thr23fiAsn90 in i soform 337 and residues
Thr54fiMet121 in CfAFP-501. (B) Overlap of isoforms 337 and 501
using the main chain of r esidues 4–33 in both proteins.
Ó ... This is
probably due to the difficulty in folding the protein, rather
than suggesting that this face of T mAFP interacts with the
ice surface.
It is important to di...
... binding-site III
(Fig. 1). To assign the contribution of bound calcium
ions at calcium binding-site III, the variant W55F, car-
rying a mutation in the respective binding site, was
included in ... disulfide bridge in G8C/N60C mimics
the occupation of calcium binding-site III
Similarly to the occupation of calcium binding-site III,
the introduction of the disulfide br...
... proposes has the ring of linguistic
authenticity; because this authenticity is rooted in
another, more literal context, the Bard also exhibits
its own Duchamp-like (if Duchamp-lite) creativity.
We ... Duchamp’s
Fountain being considered one of the most influ-
ential artworks of the 20
th
century – we shall show
that the notion of a linguistic readymade has sig-
nificant p...
... out
this process: acquisition of the data, its alignment
and its conversion into the desired format. These
are provided by WSs available in the registry.
First, we use a domain-focused bilingual
crawler
13
in ... can easily find
examples that will help them during the design
phase, being able to reuse workflows (or parts of
them) and thus avoiding reinveinting the wheel.
4...
... P1 subsite of the
inhibitor.
The most interesting amino acid at the S3 subsite is
Cys255, because it is responsible for pig POP inhibition
by bulky thiol reagents. F. meningosepticum, which has ... antitrypanosomal
drugs in widespread use are OB inhibitors [10]. In addition,
inhibition of DPP IV has been proposed as a therapeutic
approach to the treatment of type 2 diabetes...
... (respecting the orig-
inal labels of the training instances) that minimizes
test
where is monotonically increasing (we chose
unless otherwise specified) and is a
trade-off and/ or scaling parameter. (The ... standard classifier?
A: Our focus is on investigating the utility of simi-
larity information. In our particular rating-inference
setting, it so happens that the basis for...
... solid line), 60 min (thin long-dashed line),
120 min (thin short-dashed line), 240 min (thin dotted line) and
360 min (thick dotted line) of incubation, the spectrum of enzyme-
bound cobalamin ... lacking the ade-
nine ring in the upper axial ligand; a model of damaged
cofactors) for free adeninylpentylcobalamin (AdePeCbl)
(an inactive coenzyme analog containing the adenine...