Tài liệu Báo cáo khóa học: The C-terminal domain of Escheric

Tài liệu Báo cáo khoa học: Cobalamin uptake and reactivation occurs through speciﬁc protein interactions in the methionine synthase–methionine synthase reductase complex docx

... Reduction of the Co centre promotes the dissociation of the lower dimethylbenz- imidazole base of the cofactor. Consistent with this, the crystal structure of the cobalamin-binding domain Homocysteine Methionine Co Methylcob(III)alamin Cob(I)alamin Primary turnover cycle H CH 3 H 4 folate AdoHyc Cob(I)alamin Cob(II)alamin H 4 folate Co NADPH A doMet e – FAD FMN NADPH NAD...

Ngày tải lên : 18/02/2014, 08:20

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Tài liệu Báo cáo khoa học: It is all about resolution Meeting report based upon presentations at the 10th International Global BioMillennium 2006 symposium on molecular cell biology (Tbilisi, Georgia) docx

... reﬁned structure of the nuclear pore complex, enabling the construction of the trajectories of import complexes using gold-labeled substrates. Nuclear export emerges as the major regulatory mechanism of the ... independently of introns. A polarity effect reduces nonsense-mediated mRNA sensitivity to a region close to the 3¢-end of the mRNA. As a next step in the st...

Ngày tải lên : 19/02/2014, 02:20

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Tài liệu Báo cáo khoa học: Cell surface nucleolin on developing muscle is a potential ligand for the axonal receptor protein tyrosine phosphatase-r ppt

... near the limit of detection for this interaction, as successive dilution of the probe soon led to loss of signal. The low yields of the AP probe and of nucleolin, together with the inevitable ... [28,30,31]. Nevertheless, the potential ligand of PTPr within developing muscle of the chick embryo appears not be HSPG-related, and only interacts with the short prot...

Ngày tải lên : 19/02/2014, 05:20

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Tài liệu Báo cáo khoa học: A novel c-N-methylaminobutyrate demethylating oxidase involved in catabolism of the tobacco alkaloid nicotine by Arthrobacter nicotinovorans pAO1 ppt

... A. nicotinovorans is linked to the presence of the megaplasmid, pAO1 [20]. The recent elucidation of the DNA sequence of pAO1 revealed the modular organization of the enzyme genes involved in nicotine ... mutagenesis of the MABO gene The amino acid substitutions in the MABO protein were made with the aid of the Quick Change site-directed mutagenesis kit (Stra...

Ngày tải lên : 19/02/2014, 16:20

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Tài liệu Báo cáo khoa học: Secondary substrate binding strongly affects activity and binding afﬁnity of Bacillus subtilis and Aspergillus niger GH11 xylanases docx

... directly Table 1. The effect of genetic engineering of the secondary binding site of the B. subtilis and A. niger xylanases on the screening ratio. The screening ratio is deﬁned as the ratio of activity ... OSX. Especially in the case of OSX, the solubilization by the enzymes is greatly hampered upon modiﬁcation of the SBS. At the same enzyme concentration,...

Ngày tải lên : 14/02/2014, 19:20

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Tài liệu Báo cáo khoa học: Epidermal growth factor receptor in relation to tumor development: EGFR gene and cancer ppt

... Cohen’s discovery of the ‘tooth-lid factor’ led to the identiﬁca- tion of the genetic causes of certain types of human cancers, and to the genetic classiﬁcation of a variety of tumors of apparently the same ... ligand-binding domain; a transmembrane domain; an intracellular tyrosine kinase domain; and a C-terminal regulatory domain [2]. The extracellular doma...

Ngày tải lên : 16/02/2014, 09:20

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Tài liệu Báo cáo khoa học: Hsp105b upregulates hsp70 gene expression through signal transducer and activator of transcription-3 pdf

... Sche- matic representation of a series of C-terminal deletion mutants of Hsp105b. The asterisk in the Hsp105bmNLS mutant indicates the location of the mutated NLS sequence. (B) The expression plasmids ... the Hsp105b expression plasmid, the activation of the hsp70 promoter by Hsp105b was not observed (Fig. 2B). On the other hand, after deletion of the seque...

Ngày tải lên : 18/02/2014, 06:20

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Tài liệu Báo cáo khoa học: Studies on structural and functional divergence among seven WhiB proteins of Mycobacterium tuberculosis H37Rv pdf

... 7. Thermal denaturation kinetics of oxidized and reduceed apo WhiB proteins. Far-UV CD spectra of each protein showed pronounced ellipticity at 222 nm therefore, the thermal stability of the ... C-terminal cysteine of the CXXC motif is proline (Fig. S6). In WhiB2 the absence of proline and therefore of the kink might not allow the protein to attain an optimal geome...

Ngày tải lên : 18/02/2014, 12:20

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Tài liệu Báo cáo khoa học: Interleukin-1-inducible MCPIP protein has structural and functional properties of RNase and participates in degradation of IL-1b mRNA doc

... removed from the entire coding sequence of the MCPIP gene. The coding sequence lacking the PIN domain was obtained in two steps. First, the fragment of 423 bp situated in front of the PIN domain was ... independently of the presence of AREs (Fig. 6B, lanes 2 and 5). It is possible that in the region located before the AREs, consisting of 343 bp of the 3...

Ngày tải lên : 18/02/2014, 14:20

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Tài liệu Báo cáo khoa học: Pyruvate reduces DNA damage during hypoxia and after reoxygenation in hepatocellular carcinoma cells pptx

... low, whereas in the presence of the a-keto acid, the glutathione level was restored. Pyruvate is a precursor of glutathione under normoxia To further investigate the effects of pyruvate on glutathione ... with the increased abundance of enriched lactate and alanine. This is due to the blockade of the tricar- boxylic acid cycle induced by lack of oxygen. We examined...

Ngày tải lên : 18/02/2014, 16:20

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Tài liệu Báo cáo khóa học: The C-terminal domain of Escherichia coli Hfq increases the stability of the hexamer ppt