Tài liệu Báo cáo khóa học: Mutations in the hydrophobic core and in the protein–RNA interface affect the packing and stability of icosahedral viruses doc
... to the formation of cavities, one in the hydrophobic
core (M88V) and the other in the protein–RNA interaction
(T45S), decrease the stability of the capsid. Our findings
illuminate the role of packing ... different from those of other simple icosahedral
viruses [13]. The main chain of the protein subunit folds
into a five stranded antiparallel b-sh...
... euge-
nin, indicating that eugenin is indeed acting through
CCK
2
receptors.
To further investigate the interaction of eugenin with
CCK
2
receptors, we investigated the effect of eugenin
on lymphocyte ... as
stimulation of the proliferation of lymphocytes, activa-
tion of CCK receptors stimulate production of inter-
leukins and secretion of immunoglobulins on the
mucos...
... margin values of outputs given by the clas-
sifier during the parsing process. All the sentences
in the pool are processed by the current parser. We
cannot simply split the sentences in the pool into
labeled ... parser and a tool for the av-
eraged perceptron in C++ and used them for ex-
periments. We wrote the main program of active
learning and some addition...
... We initialize the sampler by randomly as-
signing each string in the training corpus a random
tree generated by the grammar. Then we randomly
select a string to resample, and sample a parse of ... shown
in Figure 1.
In this grammar and the grammars below, under-
lining indicates an adapted nonterminal. Phoneme
is a nonterminal that expands to each of the 50 dis-
tinct...
... presented in one of
four colors indicating that they:
1. are not part of an NP either in the truth or
in the output of the person's rule set
2. consist of an NP both in the truth and in
the ... recall vs. the number
of appearances in the training set of each tag
sequence for the machine and the mean of the
top 3 students is shown in...
... takes as input a sentence and a context-free
grammar and produces as output a chart like that below, indicating the
starting point and ending point of each phrase in the input string.
lnput~ ... of/ d/before/y /in
didyou
(5b) Reduction of unstressed/u/to schwa in) ,~u
(5c) Flapping of intervocalic /t/ in
hit. it
(5d) Reduction of schwa and devoicing of/ u /...
... be nominative singular-
masculine, and den Mann can only be accusative
masculine-singular. There is thus only one pos-
sible interpretation in which the dog is the biter
and the man is being bitten, ... illustrated in the top of Figure 1. This Fig-
ure shows the search tree of a small grammar
when parsing the utterance Die Kinder gaben der
Lehrerin die Zeichnung ( the...
... PPARc target genes affects the
protein degradation, destabilizing the Akt-1 protein. In
addition, the AMP-activated protein kinase pathway
can affect Akt-1 protein levels in the cell [39].
It ... is
involved in the suppression of cell proliferation and
promotion of apoptosis in endothelial and tumor cells
[20–22]. PPARc is also implicated in leptin-induced
adipoc...
... further
increase of Neu2 activity was observed during myotube
hypertrophy obtained in the presence of IGF-1; more-
over, the effects of IGF-1 were considerably reinforced
in the presence of IGF-1 ... Mammalian target of rapamycin is a
direct target for protein kinase B: identification of a
convergence point for opposing effects of insulin and
amino-acid deficiency on p...
... sorbic,
benzoic and propionic acid [7] and fail to adapt to such
stress conditions in the absence of Pdr12p. Moreover,
recent data indicate the involvement of Pdr12p in the
export of by-products of amino-acid ... at the C-terminus. The mid-
dle homology region (MHR) bridging the DNA-bind-
ing and the activation domain may control the activity
or specificity o...