Tài liệu Báo cáo khoa học: Inhibitory effects of nontoxic pr

Tài liệu Báo cáo khoa học: Inhibitory effects of nontoxic protein volvatoxin A1 on pore-forming cardiotoxic protein volvatoxin A2 by interaction with amphipathic a-helix doc

... FEBS 3171 Inhibitory effects of nontoxic protein volvatoxin A1 on pore-forming cardiotoxic protein volvatoxin A2 by interaction with amphipathic a-helix Pei-Tzu Wu 1 , Su-Chang Lin 2 , Chyong-Ing ... demonstrated that volvatoxin A consists of volvatoxin A2 and volvatoxin A1, and the hemolytic activity of volvatoxin A2 is completely abolishe...

Ngày tải lên : 19/02/2014, 06:20

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Tài liệu Báo cáo khoa học: Structural effects of a dimer interface mutation on catalytic activity of triosephosphate isomerase The role of conserved residues and complementary mutations pptx

... evolutionary selection of protein sequences is the catalytic competence of the enzyme active site. The pre- cise orientation of the functional residues is maintained by a network of interactions ... a linear gradient of 0–1 m NaCl. The fractions containing the protein were pooled and precipitated by addition of ammonium sulfate to a concentration of 75%. The precipitated...

Ngày tải lên : 18/02/2014, 11:20

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Tài liệu Báo cáo khoa học: Antimicrobial effects of H4-(86–100), histogranin and related compounds – possible involvement of DNA gyrase ppt

... attractive for further consi- deration. Potentiation of the antimicrobial activity of HN and related compounds by ATP Inﬂammation caused by infection or wounds triggers the stimulation of neutrophils, ... Medicine, University of Ottawa, Canada Histones are highly conserved proteins that play a key function in the packaging of DNA within eukaryotic cells during their division [1]...

Ngày tải lên : 18/02/2014, 14:20

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Tài liệu Báo cáo khoa học: Differential effects of Mxi1-SRa and Mxi1-SRb in Myc antagonism ppt

... FLAG-Mxi1-SRb under the control of the TET ON promoter. We monitored induction as well as expres- sion levels of the isoforms by immunoprecipitation with an FLAG antibody followed by anti-FLAG wes- tern ... R, Thomson CT, Sacchettini JC & DePinho RA (1994) Evolutionary relationships and functional conservation among verte- brate Max-associated proteins: the zebra ﬁsh homolog...

Ngày tải lên : 18/02/2014, 16:20

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Tài liệu Báo cáo khoa học: Inhibitory properties of cystatin F and its localization in U937 promonocyte cells ppt

... as one of the main means of regulation [8]. The best characterized are the cystatins, which comprise a superfamily of evolutionarily related proteins, each consisting of at least one domain of 100–120 ... dithiotreitol concentrations above 30 mm (Fig. 1B). In addition, the effect of increasing the concentration of reductant on cystatin F was followed by electrophoresis under...

Ngày tải lên : 19/02/2014, 17:20

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Tài liệu Báo cáo khoa học: Functional effects of deleting the coiled-coil motif in Escherichia coli elongation factor Ts pptx

... Parmeggiani, A. (1978) Modification of elongation-factor-Tu–guanine-nucleotide interaction by kirromycin. A comparison with the effect of aminoacyl-tRNA and elongation factor Ts. Eur. J. Biochem. ... Parmeggiani, A. (1977) Effect of kirromycin on elongation factor Tu. Location of the catalytic center for ribosome-elongation-factor-Tu GTPase activity on the elongation factor...

Ngày tải lên : 21/02/2014, 00:20

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Tài liệu Báo cáo khoa học: Identiﬁcation of critical active-site residues in angiotensin-converting enzyme-2 (ACE2) by site-directed mutagenesis docx

... Angiotensin- converting enzyme 2 is an essential regulator of heart function. Nature 417, 822–828. 6 Allred AJ, Donoghue M, Acton S & Coffman TM (2002) Regulation of blood pressure by the angiotensin ... inhibition by the classical ACE inhibitors [1,2]. After the elucidation of the crystal structure of testicular ACE (tACE), [19] a model of the active site of ACE2 was desc...

Ngày tải lên : 20/02/2014, 01:20

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Tài liệu Báo cáo Y học: Differential effects of arachidonoyl triﬂuoromethyl ketone on arachidonic acid release and lipid mediator biosynthesis by human neutrophils pot

... that inhibition of LTB 4 and PAF biosynthesis by AACOCF 3 occurs without concomitant inhibition of AA release. Generation of the common precursor pool by CoA-IT occurs by the transfer of AA from ... determined in a portion of the isolated fractions by liquid scintillation counting using a Beckman liquid scintillation counting system (Fullerton, CA, USA). Portions of PtdC...

Ngày tải lên : 22/02/2014, 07:20

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Tài liệu Báo cáo khoa học: Metabolic control of mitochondrial properties by adenine nucleotide translocator determines palmitoyl-CoA effects Implications for a mechanism linking obesity and type 2 diabetes pdf

... consumption of excess fat. However, the combination of persistent ANT inhibition by LCACs with constant activation of AMPK may have some adverse effects, because stimulation of b-oxidation ... cellular function by direct effects on a variety of enzymes and induction of apoptosis [4]. Tight regulation of intracellular concentrations of free LCACs by acyl-CoA-bindi...

Ngày tải lên : 19/02/2014, 05:20

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Tài liệu Báo cáo khoa học: Antifungal effects and mechanism of action of viscotoxin A3 docx

... generation of H 2 O 2 in spores [9,15–18]. In this work we have gained more information on the cellular targets and the mechanism of action of vis- cotoxins, by examining the interaction of VtA 3 with fungal ... permeabilization [3,16]. To further explore the interaction of the most cytotoxic viscotoxin isoform, VtA 3 , with biological membranes and obtain information...

Ngày tải lên : 19/02/2014, 07:20

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