Tài liệu Báo cáo khoa học: Inﬂuence of modulated structural dynamics on the kinetics of a-chymotrypsin catalysis Insights through chemical glycosylation, molecular dynamics and domain motion analysis pptx

... 2006 The Authors Journal compilation ª 2006 FEBS 5319 Inﬂuence of modulated structural dynamics on the kinetics of a-chymotrypsin catalysis Insights through chemical glycosylation, molecular dynamics ... revealed structural insights into the relation between the protein’s surface glycosylation, the resulting structural dynamic changes, and the inﬂuence of these on the enzyme’s collective dynamics and ... decrease the global conformational dynamics of the protein.This allowed us to then examine the effects of chemical glycosylation on the kinetics of enzymatic catalysis from both an experimental and theoretical...

Tài liệu Báo cáo khoa học: Control analysis as a tool to understand the formation of the las operon in Lactococcus lactis doc

... determination of flux control coefficients byPFK, PK and LDH. The role of the las operon is dis-cussed on the basis of the distribution of flux controlfor PFK, PK and LDH.ResultsPFK has no control ... expression of the las operon two- to three-fold the glycolytic flux will be dramatically affected.Indeed, regulation of expression of the las operon hasControl analysis of the las operon B. Koebmann ... the expression of the respective genes. We found that nei-ther the individual enzymes nor the sum of the lasenzymes had significant control on the glycolytic flux atwild-type levels. The sum of the...

Tài liệu Báo cáo khoa học: Erythrochelin – a hydroxamate-type siderophore predicted from the genome of Saccharopolyspora erythraea docx

... long-range1H–13C correlation wasdetected between the carbonyl carbon of the serine and the d-CH2 of the hOrn, which constitutes the DKP.Therefore, putting all these long-range connectionstogether, ... characterization of these compounds isgrowing and may result in the synthesis of speciﬁcinhibitors based on the structure of the pathogensiderophore [16].A promising approach for the isolation of secondarymetabolites, ... methodology. Structural and func-tional characterization was carried out relying on NMR and MSn analysis and derivatization-basedelucidation of the overall stereochemistry. Further-more, the functional...

Tài liệu Báo cáo khoa học: "Learning to Find Translations and Transliterations on the Web" doc

... compute the frequency of all the candidates identified in all snippets, and output the one with the highest frequency. 4 Experiments and Evaluation We extracted the Wikipedia titles of English and ... translations in another language. By retrieving and identifying such translation counterparts on the Web, we can cope with the OOV problem. Consider the technical term named-entity recognition. The ... more specifically the conditional random fields (CRF) model. We focus on the issue of finding translations in mixed code snippets returned by a search engine. The translations are identified,...

Tài liệu Báo cáo khoa học: Long-distance interactions between enhancers and promoters The case of the Abd-B domain of the Drosophila bithorax complex pdf

... todesignate the phenomenon when the expression of agene on one chromosome depends on the pairingwith its homologous region [14]) The degree of com-plementation in A7 depends on the size of the pro-moter ... (indica-ted by the thickness of the curved arrows) of the cis and transinteractions in favor of the latter. An increase in the trans inter-action results in an increase in the level of the functional ... However, when the combination of the PTS and the bound-ary is placed 3¢ to one of the reporter genes, the enhancer istargeted to one or the other promoter over the boundary (lowerpanel). E1 and E2:...

Tài liệu Báo cáo khoa học: "Parsing, Projecting & Prototypes: Repurposing Linguistic Data on the Web" doc

... facility by allowing structural and “construc-tion” searches.23.1 IGT detection The canonical form of IGT, as presented in Section 2.1,consists of three parts and each part is on a single line.However, ... 2009).Running the new IGT detection on the original threethousand ODIN documents, the number of IGT in-stances increases from 41,581 to 189,244. We then ran the new language ID algorithm on the IGTs, and ... available and provides additional annotation and structure, making the resource useful to the Com-putational Linguistic audience.In this paper, after a brief discussion of the previouswork on ODIN,...

Tài liệu Báo cáo khoa học: Pronounced adipogenesis and increased insulin sensitivity caused by overproduction of prostaglandin D2 in vivo pptx

... PGD2isinvolved in the activation of adipogenesis and regula-tion of insulin sensitivity in vivo. Further characteriza-tion of the role of PGD2in adipocyte differentiation and function is an important ... proceduresGeneration of H-PGDS TG mice The coding region of human H-PGDS was cloned into the downstream sites of the chicken b-actin promoter and the CMV enhancer of the pCAGGS expression vector [43]. ... temperature and amount of food intakeunder either normal or HF diet conditions in compari-son with WT mice (data not shown). The body weights of WT and TG mice were almost the same at the start of this...

Tài liệu Báo cáo khoa học: "In-Browser Summarisation: Generating Elaborative Summaries Biased Towards the Reading Context" doc

... each of the themes. The point of the SVD analysis is to discoverthese themes based on co-variance between the wordfrequencies. If words occur together, they are se-mantically related and the ... A = U SVtr. The S-matrix defines the themes of the readingcontext. The U-matrix relates the reading contextvocabulary to the discovered themes. Finally, the V-matrix relates the original sentences ... methods,SVD-link, finds the theme that the anchor text be-longs to best. This is done by consulting the V-matrix of the SVD analysis to find the highest scor-ing theme for that sentence, which we call the link-ing...

Tài liệu Báo cáo khoa học: Neuronal growth-inhibitory factor (metallothionein-3): reactivity and structure of metal–thiolate clusters* doc

... also the reason why the determination of the spatial structure of the N-terminal domain con-taining the Cd(II)3-CysS9cluster was thus precluded.For a more detailed discussion of the dynamics ... to air resulted in the slow formation of adisulﬁde linkage by cysteine oxidation of the a -domain and a concominant release of one Zn ion, but the spec-troscopic features of the Cu(I)4cluster ... a soft ligand and therefore shows a preference for soft metals. More-over the structures of metallothioneins are not rigid and hence there is little selectivity concerning the size of the ion....

Tài liệu Báo cáo khoa học : Bản chất của khủng hoảng kinh tế thế giới pdf

... la tien ten XHCN nhu the nao ? Nam 2005, Tdng thd'ng Hugo Chavez tuyen bd ring Venezudla se xay dflng CNXH the ky XXI, khac vdi CNXH the ky XX. Theo ong thi CNXH the ky XXI se da nguyen ... 63 KINH TE THE Gim Ban chdt cua cuoc khung hoang kinh te the gidi, cCfu vdt chu nghTa tu ban hay xay dung chu nghTa xa hoi the ky XXI DAO THE TUAN T 7" ien nay the gidi dang ... ma cac the liic d trong tinh trang ba't liic. Trong 10 nam nfla se tha'y rd hdn va trong 30-40 nam nfla se cd mot he thd'ng mdi xua't hien. Hoa ky se d trong mot...

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