Tài liệu Báo cáo khoa học: Bone morphogenetic protein signal

Tài liệu Báo cáo khoa học: Bone morphogenetic protein signaling in stem cells ) one signal, many consequences pptx

... 2975 MINIREVIEW Bone morphogenetic protein signaling in stem cells ) one signal, many consequences Toni U. Wagner Physiological Chemistry I, University of Wuerzburg, Germany BMP signals in stem cells Bone ... & Izpisua Belmonte JC (200 6) Nanog binds to smad1 and blocks bone morphogenetic protein- induced T. U. Wagner BMP signaling in stem...

Ngày tải lên : 19/02/2014, 00:20

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Tài liệu Báo cáo khoa học: Bone morphogenetic proteins in the early development of zebraﬁsh pptx

... family, binding to and inhibiting these signaling molecules from binding to their receptors in the extracellular space, thus inhibiting ven- tralizing activities. Of these proteins, Chordin has ... understanding of BMP func- tions, in combination with other experimental techniques. Abbreviations ADMP, anti-dorsalizing morphogenetic protein; BMP, bone morphogenetic protein; TGF...

Ngày tải lên : 19/02/2014, 00:20

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Tài liệu Báo cáo khoa học: Transient RNA–protein interactions in RNA folding docx

... the properties of the three protein classes, with the main focus being on RNA chaperones and annealer proteins. Speciﬁcally binding proteins A speciﬁc protein cofactor binds to its RNA target through ... this kinetically limiting process occurs in vivo, proteins (called RNA chaperones) have evolved that facilitate the (re)folding of RNA molecules. Here, we present an overview of how p...

Ngày tải lên : 14/02/2014, 19:20

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Tài liệu Báo cáo khoa học: Dual P2Y12 receptor signaling in thrombin-stimulated platelets – involvement of phosphoinositide 3-kinase b but not c isoform in Ca2+ mobilization and procoagulant activity pdf

... with thrombin alone (4 n M) or in combination with ADP (20 lM). (A) Effect of AR-C (10 lM) preincubation on Ca 2+ response. (B) Effect of general PI3-K inhibitor LY294002 (LY, 25 lM)onCa 2+ response. ... [Ca 2+ ] i -time integrals over 5 min. *P < 0.05, **P < 0.1 (n = 3– 5). Agonist Antagonist Peak (n M) (% versus thrombin) Integral (nM · s) (% versus thrombin) Thrombin Vehicle 646...

Ngày tải lên : 18/02/2014, 16:20

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Tài liệu Báo cáo khoa học: Gene transcription of fgl2 in endothelial cells is controlled by Ets-1 and Oct-1 and requires the presence of both Sp1 and Sp3 pdf

... spanning 39 bp in the proximal region of the fgl2 promoter. As shown in Fig. 4, mutating nucleotides from )8 7 to )8 0 (containing Oct- 1), )7 7 to )7 1 (containing Sp 1), )6 8 to )5 7 (containing Ets/Stat 3) ... cyto- toxin, and ﬁbrinogen [16–18]. Fibrinogen-like protein family members all contain ﬁbrinogen-related domains (FRED), known to represent key regions...

Ngày tải lên : 20/02/2014, 11:20

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Tài liệu Báo cáo khoa học: The Arabidopsis protein kinase Pto-interacting 1-4 is a common target of the oxidative signal-inducible 1 and mitogen-activated protein kinases docx

... mitogen-activated protein kinases (MAP- Ks), MPK3 and MPK6, in response to oxidative stress. In addition, the serine ⁄ threonine protein kinase Pto-interacting 1-2 (PTI1- 2) has been positioned downstream ... protein kinase; MAPKK, mitogen-activated protein kinase kinase; MBP, myelin basic protein; OXI1, oxidative signal-inducible 1; PDK1, 3-phosphoinositide-dependent kinase 1...

Ngày tải lên : 14/02/2014, 19:20

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Tài liệu Báo cáo khoa học: Interruption of triacylglycerol synthesis in the endoplasmic reticulum is the initiating event for saturated fatty acid-induced lipotoxicity in liver cells pdf

... obtained by ﬂow cytometric analysis in the FL1 channel (logarithmic scale). Control (Ctrl) cells (blue line), stearate-treated cells (green line), oleate (OA)-treated cells (black line) and cells ... isothiocyanate (FITC) (BD Pharmigen, San Diego, CA, USA) binding and PI staining were performed according to [44]. Following incubation with 1.0 lgÆmL )1 annexin V and 4.0 lgÆmL )...

Ngày tải lên : 14/02/2014, 22:20

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Tài liệu Báo cáo khoa học: Epidermal growth factor receptor in relation to tumor development: EGFR gene and cancer ppt

... EGFR (including EGF, transforming growth factor-a, amphi- regulin and epigen); (b) those that bind to EGFR and ERBB4 (including betacellulin, heparin-binding EGF and epiregulin); and (c) neuregulin ... ligand-binding domain; a transmembrane domain; an intracellular tyrosine kinase domain; and a C-terminal regulatory domain [2]. The extracellular domain is subdivided further into four domains....

Ngày tải lên : 16/02/2014, 09:20

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Tài liệu Báo cáo khoa học: Epidermal growth factor receptor in relation to tumor development: EGFR-targeted anticancer therapy doc

... (EGFR-TKIs), geﬁti- nib and erlotinib, compete with ATP for binding to the tyrosine kinase pocket of the receptor, thereby inhibiting receptor tyrosine kinase activity and EGFR signaling pathways ... results in EGFR signaling pathways being turned off and the cancer cells undergoing apoptosis. Moreover, EGFR mutations result in repositioning of critical residues surrounding the ATP-...

Ngày tải lên : 16/02/2014, 09:20

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Tài liệu Báo cáo khoa học: Mixed lineage leukemia: roles in gene expression, hormone signaling and mRNA processing docx

... that includes a DNA-binding domain, a ligand-binding domain and a transactivation domain. The DNA-binding domain is responsible for DNA binding speciﬁcity and dimerization, and the ligand-binding ... (HMG) domains are involved in binding DNA with low sequence speciﬁcity. LXXLL domains (also known as the NR box) are involved in interaction with nuclear receptor (NR). Plant homodomain (PH...

Ngày tải lên : 16/02/2014, 14:20

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