... Ku70,histone H1 and 28 k proteins, regardless of the type of damage (Fig. 3A, lanes 7–9). In the aggregation of lin-ear and nicked DNA, and high mobility group box(HMGB)1 and HMGB2 proteins ... nucleosomal units of chromatin inequilibrium of ionic conditions [40,41]. Probably, theextent of the aggregation would be regulated by DNAdamage-responsive chromatin factors, and one of thecandidates ... arrangement of DNA helices, allowingthe efficient catenation of the circular duplexes by Escherichia coli topoisomerases, the free exchange of DNA between neighboring aggregates by the enzyme[18], and...