Tài liệu Báo cáo khoa học: Transcriptional upregulation of inﬂammatory cytokines in human intestinal epithelial cells following Vibrio cholerae infection pptx

... proinflammatory properties of various cytokine families, were obtained in the intestinal epithelial cell line Int407 upon Vibrio cholerae infection. These proinflammatory cytokines also showed increased ... role of V. cholerae in initiating and sustaining the innate in ammatory response in intestinal epithelial cells, and the potentialcontribution of individual V. cholerae components tocytokine induction. ... eosinophils,and subpopulations of T cells [23]. In contrast to theproinflammatory cytokines, downregulation of theTable 1. Cytokines studied in human intestinal epithelial cells afterV. cholerae...

Tài liệu Báo cáo khoa học: Molecular defect of isovaleryl-CoA dehydrogenase in the skunk mutant of silkworm, Bombyx mori ppt

... becom-ing pupae in about a week after spinning (Fig. 1B).Isovaleric acid seems to be the cause of prepupallethality because injection of isovaleric acid intonormal spinning larva induces ... subtracting thereduction rate of the enzyme-excluded solution from that of the enzyme-containing solution and was expressed as nmols of 2,6-dichloroindophenol reduced per mg of protein permin. ... thesku mutant accumulates branched-chain amino acids in haemolymph, thismutant may be useful in the investigation of unique branched-chain aminoacid catabolism in insects.AbbreviationsACAD, acyl-CoA...

Tài liệu Báo cáo khoa học: Molecular determinants of ligand speciﬁcity in family 11 carbohydrate binding modules – an NMR, X-ray crystallography and computational chemistry approach doc

... addition of CtCBM11. In general, a progressive line broadening of all thecellohexaose protons was observed during titration withincreasing amounts of protein, which can be understoodas a result of ... (Fig. 1III–V), which could indicate that the corre-sponding hydroxyl groups are involved in proteinbinding.The results for the linebroadening measurements of protons H1a in the alpha and beta conﬁgurations,aHa1 ... madamm software[22] that allows the introduction of a certain degree of protein ﬂexibility in standard docking processes.The process tries to mimic a conformational bindingmodel, in which...

Tài liệu Báo cáo khoa học: Molecular aspects of rheumatoid arthritis: chemokines in the joints of patients pdf

... chemokinereceptors [2]. Chemokines are small, chemoattractant cytokines that play key roles in the accumulation of in ammatory cells at the site of in ammation. There-fore, chemokines and chemokine ... polyarticular joint dis-ease that primarily affects the small joints of the hands and feet. The in ammatory process is characterized by in ltration of in ammatory cells into the joints, leading to proliferation ... popula-tion. The in ammatory process is characterized by in ltration of in ammatory cells into the joints, leadingto the proliferation of ﬁbroblast-like synoviocytes (FLS)and the destruction of cartilage...

Tài liệu Báo cáo khoa học: The role of the ESSS protein in the assembly of a functional and stable mammalian mitochondrial complex I (NADH-ubiquinone oxidoreductase) pptx

... that the N-terminal domain is involved in protein–protein interactions with other hydrophilic domains of neighboring integral membrane subunits, and interspeciesinteractions are incompatible.From ... thebovine complex a large subdomain is made up of  20integral membrane proteins contributing > 60 transmem-brane segments. Some of these must be intimately involved in proton pumping. Another ... one might expect a protein to be insertedinto the inner membrane, but it is missing a major portion of the domain localized in the intermembrane space. Acomparison of all the known mammalian...

Tài liệu Báo cáo khoa học: "The Impact of Query Reﬁnement in the Web People Search Task" docx

... clustering task, with over 15 research groupssubmitting results in each campaign. Since the re-lease of the ﬁrst datasets, this task is becoming anincreasingly popular research topic among Infor-mation ... person. In a typicalhiring process, for instance, candidates are eval-uated not only according to their cv, but also ac-cording to their web proﬁle, i.e. information aboutthem available in the ... and n-grams beginning or ending with a stopword. Usingthe Stanford Named Entity Recognition Tool3weobtained the lists of persons, locations and organi-zations mentioned in each document.Additionally,...

Tài liệu Báo cáo khoa học: Electrostatic role of aromatic ring stacking in the pH-sensitive modulation of a chymotrypsin-type serine protease, Achromobacter protease I pdf

... thisprotease at pH9 [10]. Further interest in the aromaticstacking is in the role of the electrostatic properties in enzymatic catalysis of API, and in distinguishing thefunctionally catalytic ... andW169A, deviates from the original position. In the struc-tural deviation, the solvent ASA of the side-chain of His210increased with the decrease in size of the side-chain atresidue 169 (Table ... effect of the size of the residue at position 169 may berelated to the solvent accessibility of the side-chain of His210 (Fig. 3C). When the accessibility of the side-chain of His210 increased,...

Tài liệu Báo cáo khoa học: "The Use of Ooject-Special Knowledge in Natural Language Processing" doc

... the introduction of stereotyplc knowledge of objects into the conceptual analysis of text. By encoding information in OP descriptions, we were able to increase the interpretive power of ... primitive, indicating that they are containers (link = INSIDE) with default object contained being wine. The second, the COMMON-SOURCE test, looks for known SOURCEs of wine by following the associative ... completes the linking of tne causal chain between tne events described in the sentence. Second, it causes the filling of empty slots appearing in either the enabled act or In the enabling act, wherever...

Tài liệu Báo cáo khoa học: "Some Uses of Higher-Order Logic in Computational Linguistics" pdf

... the process of finding proofs. In a more specific sense, there are sublogics of a higher-order logic in which the process of constructing proofs is not much more complicated than in similar ... formula of type a -~ ft. We assume that the following symbols, called the log- ical constants, are included in the set of constants of the corresponding type: true of type o, ~ of type o ... One of the purposes for providing a representation for concepts is so that inferences that involve them can be described. One kind of inference that is of particular interest is that of...

Tài liệu Báo cáo khoa học: Molecular basis of glyphosate resistance – different approaches through protein engineering doc

... accompanied by improved bind-ing to longer ligands (up to ﬁve atoms in the mainchain) and retained binding to shorter ligands [55]. Of the 21 changes in the evolution of R7 fromnative GLYAT ... d-amino acid oxidase [47]. In B. subtil-is, GO is involved in biosynthesis of the thiazolemoiety of thiamine pyrophosphate (vitamin B1). Thisreaction requires the direct transfer of the imine ... An in silico dockinganalysis of glyphosate binding at the GO active siteshowed that glyphosate is bound in the same orienta-tion as inferred for glycine (with the phosphonate moi-ety pointing...

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