... function of the HSF family
FEBS Journal 277 (2010) 4112–4125 ª 2010 The Authors Journal compilation ª 2010 FEBS 4125
MINIREVIEW
The heat shock factor family and adaptation to
proteotoxic stress
Mitsuaki ... heat
shock factor system: Hsf3 and Hsf4. Cell Stress Chap-
erones 4, 86–93.
9 Pirkkala L, Nykanen P & Sistonen L (2001) Roles of the
heat shock...
... have been proposed for the binding of the SRL to the
active site of RTA in which the principal difference lies in the
conformation of the second ÔGÕ in the target GAGA motif
in the 28S rRNA substrate. ... between
RTA and the rRNA backbone in this area might be
required to maintain the tetraloop in the optimum
conformation for catalysis. Both the catalytic role of...
... (2003) Responses to the proinflammatory cyto-
kines interleukin-1 and tumor necrosis factor alpha in
cells derived from rheumatoid synovium and other joint
tissues involve nuclear factor kappaB-mediated ... the
recognition sites of the NFAT and Ets factors led us to
investigate the potential involvement of the epithelial
specific Ets factor 1 (ESE-1 ⁄ ESX ⁄ ELF3 ⁄ ERT...
... present; and
the repair to Denver replaces the reparandum.
Shriberg and Stolcke (1998) studied the location
and distribution of repairs in the Switchboard cor-
pus (Godfrey and Holliman, 1997), the ... identifies and defines
three distinct parts of a speech disfluency, referred
to as the reparandum, the interregnum and the re-
pair. Consider the following uttera...
... (1999)
Dementia, gliosis and expression of the small heat
Y. Sun and T. H. MacRae Small heat shock proteins and disease
FEBS Journal 272 (2005) 2613–2627 ª 2005 FEBS 2625
shock proteins Hsp27 and [alpha]B-crystallin ... lens and guard against ischemic and reper-
fusion injury due to heart attack and stroke. On the other hand, mutated
sHSPs are implicated in disease...
... they can increase
the amount of available phosphate by interacting together. Additionally,
fusing PhyH-DI to a single-domain phytase appears to be an efficient way
to improve the activity of the ... pH
(6.0–8.0) and at low temperatures (0–35 °C). We focus
on the function and relationship of the two single
domains. Additionally, the possibility that fusion of the
PhyH N-...
... of the tomato SlPti1 in tobacco caused
enhanced HR in leaves when challenged with P. syrin-
gae pv tabaci expressing AvrPto [17]. On the other
hand, expression of the tomato SlPti1 cDNA in the
rice ... with PTI1-4 fused to the GAL4 DNA-binding domain
or the empty vector pBD, with AGC2-2 or AGC2-3 fused to the acti-
vation domain or the empty vector pAD. The left-hand sid...
... include a factor named CDF-1, which was
observed to bind to the CDE ⁄ CHR elements in the
Cdc25C and cyclin A promoters [82,83]. However,
many attempts by several groups to clone and further
characterize ... the E2F transcription factor
family [13]. Since the discovery of the first three genes
regulated by CDE ⁄ CHR tandem sites, many other
important cell cycle-regula...
... signalling and
resistance to apoptosis through downregulation of tBid, providing further
details on how EGF receptor and proteasome inhibitors can contribute to the
induction of apoptosis and the treatment ... [16,17]. The BH3
domain-only proteins are a subfamily of the Bcl-2
family involved in the initiation of apoptosis through
the mitochondrial pathway. The key ev...
... performed to determine the
role of the ARE II and ARE IV sites in the binding of
proteins to the ‘extended ARE’. Binding of cytoplas-
mic proteins to the ‘extended ARE’ probe was first
shown to be ... samples and the plates were returned to
the incubator for further incubation.
In vitro transcription and RNase protection assay
and northern hybridization
A cDNA l...