... between the inside of the cell and the outside of the cell. The difference is known as the membrane potential. • Because the membrane potential is created by the difference in the concentration of ... between the capillaries and the cells (Reichart, 1999). The concentration of minerals in the ECM, the composition of proteoglycans, the molecular weight of the proteoglycans, the amount of bound ... of bound water in the ECM, and the pH of the ECM control the filtering aspect of the ECM. • The ECM is a transit area for the passage of nutrients from the bloodstream into the cells and for...