... metabolism, the hormonally active form of vitamin D3, 1a, 25-dihydroxyvitamin D3, displays anti-cancer, immunoregulatory and endocrine effects, and is also a potent antiproliferative and differentiation-inducing ... University of Western Australia, Crawley, Australia2 Department of Pharmaceutical Sciences, College of Pharmacy, University of Tennessee Health Science Center, Memphis, TN, USA3 Department of Pharmacognosy ... Pathology and Laboratory Medicine and the Center for Cancer Research, University of Tennessee Health Science Center,Memphis, TN, USA5 Department of Pharmacology and the Center for Cancer Research,...