... substances, like strong acids and alkalis, can chemically burn the skin. Others can irritate the skin. Many chemicals, particularly organic solvents, dissolve the oils in the skin, leaving ... at which substances first contact the body are the skin, eyes, nose, throat, and lungs. Many toxic substances can also enter the body and travel in the bloodstream to internal organs. Effects ... reproduction include a decreased ability to conceive children (infertility, sterility, abnormal sperm, or a Understanding Toxic Substances An Introduction to Chemical Hazards in the Workplace State...