... solid line), in the presence of100 lM neurotoxin (•, dotted line), in thepresence of 200 lM neurotoxin ( , dottedline) and in the presence of neurotoxin and 50 lM dopamine (h, dashed line).Modulation ... K,Kuroiwa Y et al. (2008) RNA-binding protein TLS is amajor nuclear aggregate-interacting protein in hunting-tin exon 1 with expanded polyglutamine-expressingcells. J Biol Chem 283, 6489–6500.25 ... pooled and the amount of protein was determined by the bicinchoninicacid assay [38] using bovine serum albumin as a standardprotein. The pooled eluate fractions were dialysed againstwater and...