— cad of multiple sclerosis ms on mri
báo cáo hóa học: " The burden of multiple sclerosis: A community health survey" pot
... terms, one may conclude that the HRQL of burden associated with MS is substantially higher than any one of these four other chronic conditions or in any combination of three of these four conditions ... scores for respondents with and without MS, but no other chronic conditions MS Overall HUI3 score Vision Hearing Speech Ambulation Dexterity Emotion Cognition Pain General Population Mean Difference ... four conditions Others have also reported that patients with MS are among one of the most severely impaired in comparison with other chronic conditions such as cardiovascular conditions, cancer,...
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báo cáo hóa học: " Oral administration of the KATP channel opener diazoxide ameliorates disease progression in a murine model of multiple sclerosis" ppt
... Neuroinflammation 2011, 8:149 http://www.jneuroinflammation.com/content/8/1/149 in EAE and at the edges of MS lesions and NO is one of the main effectors of demyelination [37,38] Microglial IL-6 secretion ... Domoki F, Katakam PV, Bari F: Mitochondrialmediated suppression of ROS production upon exposure of neurons to lethal stress: mitochondrial targeted preconditioning Adv Drug Deliv Rev 2008, 60:1471-1477 ... different mechanisms, including the facilitation of glutamate uptake [52] and amelioration of mitochondrial and connexin 43 dysfunction [53] We also observed a decrease in nitrite production and inflammatory...
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báo cáo hóa học:" Effect of multiple micronutrient supplementation on survival of HIV-infected children in Uganda: a randomized, controlled trial" ppt
... common cause of death was pneumonia accounting for 20/53 (37.7% )of the deaths: eight of the 20 children died of severe pneumonia, six of severe acute malnutrition with severe pneumonia, three of ... SAEs The paediatrician decided on the relationship to the intervention using a set of conditions or known side effects of micronutrients All SAEs warranted stoppage of the trial supplement when ... this dosing of multiple micronutrients We hypothesized that daily administration of twice the recommended dietary allowance of multiple micronutrients to HIV-infected children aged one to five...
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báo cáo hóa học:" The burden of multiple sclerosis: A community health survey" potx
... terms, one may conclude that the HRQL of burden associated with MS is substantially higher than any one of these four other chronic conditions or in any combination of three of these four conditions ... scores for respondents with and without MS, but no other chronic conditions MS Overall HUI3 score Vision Hearing Speech Ambulation Dexterity Emotion Cognition Pain General Population Mean Difference ... four conditions Others have also reported that patients with MS are among one of the most severely impaired in comparison with other chronic conditions such as cardiovascular conditions, cancer,...
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Handbook of Multiple Sclerosis pdf
... Pathological Anatomy: Illustrations of the Elementary Forms of Disease London: Longmans, 1838 Compston DAS The 150th anniversary of the first depiction of the lesions of multiple sclerosis J Neurol Neurosurg ... failure of the early recovery mechanisms with the reappearance of conduction block in chronically demyelinated fibers also contributes (49) D Diagnosis A practical consequence of the demonstration of ... international group of investigators is working under the auspices of the International Federation of Multiple Sclerosis Societies to just that III CONCLUSION This short account of the history of demyelinating...
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báo cáo hóa học: "The impact of regular physical activity on fatigue, depression and quality of life in persons with multiple sclerosis" pot
... recent review of exercise intervention studies in persons with MS, found Figure Quality of life scores in people with multiple sclerosis Quality of life scores in people with multiple sclerosis Error ... in persons with MS Due to the cross-sectional nature of this study we cannot provide definitive conclusions on the direction of causality between activity levels and fatigue, depression and QoL ... fatigue), social functioning (limitations in social functioning due to physical or emotional problems), role-emotional (limitation in usual activities due to emotional problems) and mental health...
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báo cáo hóa học: " Effects of glatiramer acetate on fatigue and days of absence from work in first-time treated relapsing-remitting multiple sclerosis" doc
... Long-Term Study of Brain (1)H-MRS Study in Multiple Sclerosis: Effect of Glatiramer Acetate Therapy on Axonal Metabolic Function and Feasibility of Long-Term (1)H-MRS Monitoring in Multiple Sclerosis ... interferon-induced fatigue in MS patients [32] In contrast to the interferon's, the specific action of glatiramer acetate to improve MRS markers of axonal injury in multiple sclerosis might contribute ... non-specific consequence of improved overall disease status in treated patients or alternatively result from a specific action of the medication on the pathophysiology of multiple sclerosis fatigue...
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báo cáo hóa học:" The impact of regular physical activity on fatigue, depression and quality of life in persons with multiple sclerosis" pdf
... recent review of exercise intervention studies in persons with MS, found Figure Quality of life scores in people with multiple sclerosis Quality of life scores in people with multiple sclerosis Error ... in persons with MS Due to the cross-sectional nature of this study we cannot provide definitive conclusions on the direction of causality between activity levels and fatigue, depression and QoL ... fatigue), social functioning (limitations in social functioning due to physical or emotional problems), role-emotional (limitation in usual activities due to emotional problems) and mental health...
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báo cáo khoa học:" Development of a patient reported outcome scale for fatigue in multiple sclerosis: The Neurological Fatigue Index (NFI-MS)" pptx
... been upon the impairment of function as opposed to the social impact of fatigue Nevertheless, the multi-dimensional nature of fatigue in MS lends itself to an exploration of the role of fatigue ... probability values non-significant (5% alpha with Bonferroni correction for the number of items); b individual item fit residual, by convention, within ± 2.5 (99% CI); c mean and SD of both summary ... http://www.hqlo.com/content/8/1/22 Page of 10 Table Comparison of the evaluation and validation sample characteristics Characteristic Evaluation sample Validation sample Difference between evaluation and validating...
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Tài liệu Báo cáo khoa học: Analysis of proteins and peptides on a chromatographic timescale by electron-transfer dissociation MS ppt
... compilation ª 2007 FEBS 6271 ETD -MS analysis of peptides and proteins N D Udeshi et al dimethylation of Arg, monomethylation, dimethylation and trimethylation of Lys, acetylation and ubiquitination of ... Coon JJ (2007) Implementation of electron transfer dissociation on a hybrid linear ion trap-orbitrap mass spectrometer In Developments in Ion Trap MS Proceedings of the 55th ASMS Conference on ... acquisition of a full mass spectrum and ETD ⁄ PTR MS ⁄ MS spectra on the six most abundant ions every s (400–500 ms per spectrum) Throughout the automated LC -MS ⁄ MS experiment, the ion–ion reaction...
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Báo cáo khoa học: Multiple effects of DiS-C3(5) on mitochondrial structure and function pot
... addition of DiS-C3(5) £ 10 lM caused deceleration of mitochondrial oxygen consumption but > 20 lM caused acceleration These actions of DiS-C3(5) on Ó FEBS 2004 Effects of DiS-C on mitochondrial ... acceleration and deceleration of oxygen consumption were observed, depending on the concentration of the dye At higher concentrations such as 50 lM, DiS-C3(5) caused acceleration of mitochondrial ... mitochondrial oxygen consumption [6–8] These actions of cyanine dyes were attributable Fig Effects of DiS-C3(5) on the turbidity of mitochondrial suspensions (A) and on permeability of mitochondrial...
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Assessment and Management of the Elderly Patient with Multiple Sclerosis pot
... approaches in the context of the aging MS patient An Overview of MS in Aging The hallmarks of MS are central nervous system (CNS) inflammation, demyelination, axonal degeneration and gliosis which ... with multiple sclerosis Pain Pain is one of the most common symptoms of MS and can be seen in more than half of all patients with MS Pain can either be neuropathic or nociceptive Patients with MS ... 2012:4 Elderly patient with multiple sclerosis as CVA and CAD Many symptoms of diabetes can overlap or mimic symptoms of MS For example, the neuropathy of diabetes consists of pain and paresthesias...
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báo cáo hóa học: "Rasch analysis of the Multiple Sclerosis Impact Scale (MSIS-29)" pot
... Multiple Sclerosis Quality of Life Inventory (MSQLI) [12], the Functional Assessment of Multiple Sclerosis (FAMS) [13], the Multiple Sclerosis Functional Composite (MSFC) [14], the UK Neurological ... physical impact dimension (MSIS-29-PHYS: consisting of 20 items) and the psychological impact dimension (MSIS-29-PSYCH: consisting of nine items) measure related, but distinct, constructs (correlatingr ... removal of one person (N = 91) Targeting map for the 20-item MSIS-29-PHYS after rescoring and removal of one person (N = 91) relation matrix falling below 0.3 Dimensionality of the rescored MSIS-29-PHYS...
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báo cáo hóa học: " Fatigue characteristics in multiple sclerosis: the North American Research Committee on Multiple Sclerosis (NARCOMS) survey" pot
... characteristics of fatigue among persons with MS in the North American Research Committee on Multiple Sclerosis (NARCOMS) Patient Registry, a project of the Consortium of MS Centers (CMSC) A longitudinal ... and Quality of Life Outcomes 2008, 6:100 Background Chronic fatigue is one of the most common disabling symptoms among persons with multiple sclerosis (MS) , interfering with, and considerably ... difference of years) than those with mild to moderate fatigue In terms of disease duration, fatigue increased steadily for people with MS durations of one to 14 years, but for those with longer durations...
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Báo cáo hóa học: "Adaptive robot training for the treatment of incoordination in Multiple Sclerosis" doc
... epochs, each consisting of the presentation of all three targets (one for each direction), in random order Each rehabilitation session consisted of six phases: (i) Familiarization (5 epochs, ... Journal of NeuroEngineering and Rehabilitation 2010, 7:37 http://www.jneuroengrehab.com/content/7/1/37 Page of 11 best reflects the operation of the feed-forward component of control Late portions of ... treatment of incoordination in Multiple Sclerosis Journal of NeuroEngineering and Rehabilitation 2010 7:37 Submit your next manuscript to BioMed Central and take full advantage of: • Convenient online...
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Báo cáo hóa học: " Objective assessment of motor fatigue in multiple sclerosis using kinematic gait analysis: a pilot study" docx
... for MS patients compared to healthy persons and that these Table Differential diagnosis of fatigue or causes of secondary weakness/tiredness in MS MS related causes for lack of energy Non -MS related ... lack of energy Depression Depression Nocturia Thyroid function Sleep disturbance Anemia Spasticity, paresis, uneconomic movement Infection (bladder) Lack of condition Electrolytes Side effects of ... Cognitive Functions (FSMC): validation of a new instrument to assess multiple sclerosis- related fatigue Multiple Sclerosis 2009, 15(12):1509-1517 34 Guidelines MSCfCP: Fatigue and Multiple Sclerosis: ...
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báo cáo hóa học: " Effect of pioglitazone treatment in a patient with secondary multiple sclerosis" doc
... fluid-attenuated inversion recovery (FLAIR) MRI images showing confluent demyelination Axial T1-weighted fluid-attenuated inversion recovery (FLAIR) MRI images showing confluent demyelination MRIs were taken ... performed, one 18 months after initiation of pioglitazone and the second 10 months later (Figure 1) There was no perceptible change in overall brain atrophy, extent of demyelination, or in Gd-enhancement ... of multiple sclerosis: results of an international survey National Multiple Sclerosis Society (USA) Advisory Committee on Clinical Trials of New Agents in Multiple Sclerosis Neurology 1996, 46:907-911...
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báo cáo hóa học: " Production of IL-16 correlates with CD4+ Th1 inflammation and phosphorylation of axonal cytoskeleton in multiple sclerosis lesions" pptx
... severity of relapsing disease, of inflammation, and of demyelination, as well as the extent of axonal damage [19] We provided evidence of regulation of IL-16 in EAE, which suggested that production of ... of axonal cytoskeleton lesions Alterations of axonal cytoskeleton are suggested by markedly increased levels of phosphorylated medium and heavy chains of neurofilament [NF (M+H)P] in MS lesions ... one half those of acute lesions but still markedly higher than those of controls The observed patterns of regulation of [NF(M+H)]P correspond to those of IL-16 (Fig 1) in MS lesions Abnormalities...
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báo cáo hóa học: " Saliva soluble HLA as a potential marker of response to interferon-β1a in multiple sclerosis: A preliminary study" pdf
... subjects Number of MS patients Age (Mean ± SD) MS duration prior to diagnosis Number of T1-weighted post-contrast enhancing lesions At least one at month At least one at month Number of relapses ... images Comparison of brain MRI at months and did not show any new contrast-enhancing lesions Comparison of the mean volumes of T2-weighted lesions as well as the average count of T1-weighted ... IFN-γ Since monocyte-derived HLA-G inhibits autologous CD4 T cell activation, its upregulation by IFN-β was considered as one of the mechanisms of action of IFN-β In the present study, longitudinal...
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báo cáo hóa học: " Serum lipid profiles are associated with disability and MRI outcomes in multiple sclerosis" pptx
... condition Additional material Additional file 1: Additional file 1contains MRI Acquisition Protocol, Image Analysis methods and Table S1 Acknowledgements Support from the National Multiple Sclerosis ... interpretation and manuscript preparation RZ contributed to study design, MRI data acquisition, data interpretation and manuscript preparation EC contributed to MRI data acquisition AD contributed ... Serono, Pfizer, Novartis, the National Multiple Sclerosis Society, the Department of Defense, National Institutes of Health and National Science Foundation He received compensation as a consultant...
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