‎4 8 top view of the recombinant intestinal villi at adult stage without sectioning the white lines show the border of either side of the intestinal villi the lines also show where apoptosis happens β actin dtomato red β actin yfp yel

The structure basis for burkholderia pseudomallei hcp induced multinucleated giant cell formation

Ngày tải lên : 10/09/2015, 09:25

... Darwin, northern Australia, where it is the most common cause of fatal community-acquired septicemic pneumonia.9 The Top End of northern Australia, which is the second northernmost point of the continent, ... RPMI at a rate of mL/min to final volume of mL The sides of the tubes were further rinsed with mL of RPMI The fused cells were centrifuged washed once and resuspended in 20 mL of HAT medium They ... non-pathogenic bacteria .82 ,83 The unifying theme to date on the role of T6SS is the delivery of bacterial effectors into the target eukaryotic and prokaryotic cells Hence current models of T6SS often...

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Báo cáo khoa học: "The interaction between different types of activated RAW 264.7 cells and macrophage inflammatory protein-1 alpha" potx

Ngày tải lên : 09/08/2014, 09:20

... RT-PCR The ability of LPS-stimulated MF to express MIP-1a mRNA also was stronger than that of IL-4- or IL-13-stimulated MF (p < 0.01) (see Figure 4B) Therefore, we conclude that at the level of either ... the optimal activation of MF in vitro must be investigated The results of our experiments also show that M1 expresses arginase activity that is significantly weaker than that of M2a Results of ... characterization of three activated macrophage populations J Leukoc Biol 2006, 80 :12 98- 1307 24 Mosser DM, Edwards JP: Exploring the full spectrum of macrophage activation Nat Rev Immunol 20 08, 8: 9 58- 969...

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Báo cáo khoa học: Ascorbic acid-pretreated quartz enhances cyclo-oxygenase-2 expression in RAW 264.7 murine macrophages pdf

Ngày tải lên : 23/03/2014, 10:20

... 264.7 cells The inducible enzyme COX-2 is expressed in the early stages of the inflammatory response and catalyses the first step of the synthesis of PGE2, an important inflammatory mediator COX-2 ... concentration [14] Furthermore, the above results indicate that ROS generation is higher in cells challenged with AA-treated compared with untreated quartz and that, at the lowest particle concentration, ... to AA-treated quartz [7 ,8, 18 20] Transcription of COX2, which catalyzes the first step of PGE biosynthesis, occurs in the early stages of macrophage activation and is known to be triggered by quartz...

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Báo cáo y học: "Stable expression of a recombinant human antinucleosome antibody to investigate relationships between antibody sequence, binding properties, and pathogenicity" doc

Ngày tải lên : 09/08/2014, 06:23

... mice The major objective of this was to investigate possible effects of the R27aS mutation on pathogenic potential of antibody B3 Table shows the results of two separate experiments The cell lines ... groups is the lack of evidence of deposition of the antibodies in the kidneys of the mice One reason for this may be that the level of human IgG measured in the sera was very low in both the CHO-B3 ... suggests that the earlier deaths of mice in the CHO-B3 group were due either to the difference in the antibody sequence or to some direct effect of the cell line that is not so evident with the CHO-B3(R27aS)...

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Báo cáo y học: "A randomized, double-blind study of AMG 108 (a fully human monoclonal antibody to IL 1R1) in patients with osteoarthritis of the knee" pdf

Ngày tải lên : 12/08/2014, 17:22

... 68% ), and most were white (Part A, 98% ; Part B, 83 %) The mean age was 61 years for patients in both parts of the study The mean duration of OA at baseline of Part A was years for the AMG 1 08 ... well-balanced at 82 % (77/94) and 84 % (74 /88 ), respectively The overall incidence of infections in these two SC groups appeared to be higher in the AMG 1 08 group at 27% (25/94) vs 21% ( 18/ 88) for placebo; ... increase (Table 3) Because of the non-linear nature of the PK data and insufficient data for the terminal phase of the concentration-time profile, the half-life of AMG 1 08 could not be determined...

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Báo cáo y học: "Identification of signaling components required for the prediction of cytokine release in RAW 264.7 macrophages" pdf

Ngày tải lên : 14/08/2014, 16:21

... combinations of one or more predictors (from the original list of all significant predictors) During this phase, it is also required that the signs of the coefficients of the predictors in the ... understanding the regulation of the expression and release of these mediators is crucial for understanding the course of the inflammation process Here we propose models that derive the responses of seven ... model is the combination of the minimal PP-model and the minimal residuals model The procedure for the identification of the minimal model containing the necessary and sufficient set of predictors...

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Báo cáo Y học: Complexation of ytterbium to human transferrin and its uptake by K562 cells pot

Ngày tải lên : 08/03/2014, 09:20

... respectively, and the same molecular absorption coefﬁcient We also noticed that the higher the bicarbonate concentration, the higher degree of saturation of trnasferrin by Yb3+ (data not shown) The two ... [23] The iron saturation of FeC-Tf and Fe2-Tf was also estimated from the ratio of A 280 nm/A465nm [23] The Yb-Tf solution was prepared by mixing YbCl3 and apo-Tf solutions in a molar ratio of 2.5 ... the C-lobe [29] Upon the addition of mol equiv of Lu3+, a new signal appeared at 2.097 p.p.m (signal C), while the signal at 2. 088 p.p.m split into two (A and B) The relative intensities of the...

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báo cáo hóa học:"Interdependency of CEACAM-1, -3, -6, and -8 induced human neutrophil adhesion to endothelial cells" pdf

Ngày tải lên : 18/06/2014, 15:20

... review of the manuscript 17 Supported in part by the American Heart Association, Minnesota Affiliate, NIH grant CA606 58, the Office of the Vice President for Research and Dean of the Graduate ... (CEA) expressed on Page 10 of 12 (page number not for citation purposes) Journal of Translational Medicine 20 08, 6: 78 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 CHO cell surface: homophilic ... regulated dimerization of cell-cell adhesion molecule (C-CAM) in epithelial cells Biochem J 1996, 320(Pt 3) :84 7 -85 3 http://www.translational-medicine.com/content/6/1/ 78 85 86 87 88 89 90 91 92 93...

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báo cáo hóa học: " Human brain endothelial cells endeavor to immunoregulate CD8 T cells via PD-1 ligand expression in multiple sclerosis" pdf

Ngày tải lên : 19/06/2014, 22:20

... correlating with the absence of PD-1 on infiltrating CD8 T cells Therefore, we speculate that the BBB capacity to control cell entry into the CNS is impaired in MS patients, leading to the entry of ... in the EAE model [26,27] We can speculate that PD-1 ligand expression by the CNS-endothelium may play a role in regulating the migration of other activated immune cells expressing the cognate ... Journal of Neuroinflammation 2011, 8: 155 http://www.jneuroinflammation.com/content /8/ 1/155 regulate the migration of CD8 and CD4 T cells into the CNS We used a well-established in vitro model of the...

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Báo cáo y học: " Human embryonic stem cell (hES) derived dendritic cells are functionally normal and are susceptible to HIV-1 infection" pot

Ngày tải lên : 10/08/2014, 05:20

... levels of stimulation decreased at higher ratios The percent stimulation of Tcells by hES-DCs and FL-DCs were similar at the ratios 1:500 to 1:4000 These results demonstrated the capacity of hES-DCs ... utilization of these cells for hematopoietic cell therapy [9] Recently we demonstrated derivation of phenotypically and functionally normal macrophages from hES-CD34+ cells and established that they ... towards expanding the use of hES cells for novel applications In this regard, the ability to generate cells of the hematopoietic system has considerable potential in several areas of clinical and...

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Step up to IELTS units 7-11 with key.pdf

Ngày tải lên : 07/08/2012, 12:18

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Quy trình bảo dưỡng, sữa chữa ô tô con 4-7 chỗ. thiết kế trạm bảo dưỡng, sữa chữa theo tiêu chuẩn

Ngày tải lên : 29/04/2013, 16:30

... chữa - Các chi tiết bắt chặt : bulông, đai ốc, chốt, vòng đệm, then … để theo nhóm kích thước theo - Những chi tiết mà phải gia công theo sử dụng tiếp không nên tháo rời Phải đánh dấu để bảo đảm ... Nhiệt độ mở van Độ nâng van 950C p suất mở van an toàn Tiêu chuẩn Tối thiểu 80 – 84 0C 8. 5 mm hay 0.95 – 1.25 kG/cm2 0.8kG/cm2 Bảo dưỡng: Kiểm tra chất lượng nước làm mát: Không có cặn bẩn, gỉ đọng ... hay chổi sắt( với điện cực platin không dùng chổi than) - Nếu điện cực bò bám muội bon ướt, làm bugi máy làm sau làm khô Áp suất khí tiêu chuẩn: 588 kPa (6 kgf/cm2, 85 psi) - Thời gian tiêu chuẩn:...

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8 cách đơn giản tăng tốc windows 7

Ngày tải lên : 13/08/2013, 12:04

... HKEY_LOCAL_MACHINE, mở dần theo đường dẫn: /Software/ Microsoft/Windows/Current Version/ Explorer/RemoteComputer/NameSpace Bạn thấy key có tên kiểu mã số {D6277990-4C6A-11CF-8D87- 00AA0060F5BF} Hãy ... khoá sau: HKEY_LOCAL_MACHINE \SOFTWARE \Microsoft \Dfrg \BootOptimizeFunction Bạn nhìn qua cửa sổ bên phải, double click vào biểu tượng Enable Trong khung Value Data, bạn thay đổi giá trị Y thành ... Desktop Ở khung bên phải bạn tìm chữ MenuShowDelay bấm đúp vào sửa số khung thành > OK Tăng tốc tắt máy: - Start > Run gõ Regedit Mở theo nhánh sau HKEY_CURRENT_USER > Control Panel > Desktop...

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cac nguyen to thuoc nhom 7

Ngày tải lên : 11/09/2013, 01:10

... chất hiđro với halogen HF HCl HBr HI Nhiệt độ nóng chảy (0C) - 83 ,0 - 114,2 - 88 ,0 - 50 ,8 Nhiệt độ sôi (0C) 19,5 - 84 ,9 - 66,7 - 35 ,8 N.Lượng lk H – X (kJ/mol) 565 431 364 297 Độ dài lk H – X (Å) ... tố: flo(F), clo(Cl), brom(Br), iot(I) atatin (At) , gọi chung halogen NHÓM VIIA (HALOGEN) Đặc điểm chung F Electron hóa trị Br I At Số thứ tự Cl 17 35 53 85 2s22p5 3s23p5 4s24p5 5s25p5 6s26p5 Bán ... (Å) 0,64 0,99 1,14 1,33 1,40 N.lượng ion hóa I1 17,42 13,01 11 ,84 10,45 9,50 Ái lực electron (eV) 3, 58 3 ,81 3,56 3,29 - Độ âm điện 3, 98 3,16 2,96 2,66 2,20 (eV) NHÓM VIIA (HALOGEN) Đặc điểm chung...

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Essential guide to writing part 7

Ngày tải lên : 20/10/2013, 03:15

... the beginning The predicate—that is, what is asserted about the topic—requires several sentences These constitute the body of the paragraph, developing or supporting the topic in any of several ... piece of writing Another eye-catching form of topic statement is the fragment, the grammatically incomplete sentence, as in the second paragraph of this passage (italics added): Approaching the ... two forms qualification specification of the two forms Examining whether the sentences of a paragraph correspond with its ideas is a good test of the coherence of the paragraph The correspondence...

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British English A to Z - past 7

Ngày tải lên : 23/10/2013, 13:20

... regular driving The one nearest the center is called the off -side lane, and is used for passing The terms near -side and off -side can also refer to the sides of a vehicle: e.g., the off -side front ... leaves the metals in Britain it has been derailed rails meteorological office weather bureau And the much reviled official whom the Americans call the weatherman is the clerk of the weather in ... projecting over the entrance to a theater or other public hall, and the word evokes the image of large illuminated letters spelling out the names of stage and movie stars, double features, and smash...

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Đề thi HKI Toán 7-Năm 2010.2011 I m«n to¸n - líp 7

Ngày tải lên : 27/10/2013, 10:11

... 0.25đ câu a b c d đáp án a c d b Tự luận: THPT: Mỗi câu 0.5đ a 20 b -36 c Tìm x: Mỗi câu 0.5đ a x= 28 b x=9 c x= 16 x= Gọi ẩn viết đợc tỷ lệ thức: 1đ - áp dụng tính chất dãy tỉ số có kết đúng: 1đ...

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Tài liệu The Insider’s Guide to PR: Chapter 7 A GLOSSARY OF PR SPEAK doc

Ngày tải lên : 23/12/2013, 00:15

... News Conference: the live dissemination of news information by an organisation to invited media The format is usually a presentation of information by the organisation followed by a question and ... number of marketing communications techniques in order to deliver a consistent set of messages The aim is to achieve seamless communication with the audience • Internal Communications: information ... The Insider’s Guide to PR: Chapter • Financial PR: the efforts of a publicly-held company, or one that is on the way to a public flotation, to communicate with shareholders,...

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Tài liệu Thêm Dropbox vào menu Send To trong Windows 7, XP và Vista ppt

Ngày tải lên : 26/01/2014, 04:20

... Windows Vista Đầu tiên, copy đường link sau vào Windows Explorer mục Search menu Start %APPDATA%\Microsoft\Windows\SendTo Nếu bạn có dropbox Favorites, phải chuột vào folder chuyển tới folder Send ... vào Send To hệ điều hành XP Trong hệ điều hành Windows XP, vào Control Panel > Folder Options > Show hidden files and folders Chuyển tới C:\Documents and Settings\[User Name]\SendTo (User Name...

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Tài liệu Human Resources Development Division Head Office, 7, Bhikaiji Cama Place, New Delhi -110607 docx

Ngày tải lên : 16/02/2014, 11:20

... 17 GUWAHATI 18 HYDERABAD 19 10 JAMMU 20 11 JAIPUR 21 12 KOLKATA 22 13 LUCKNOW 23 14 MUMBAI 24 15 PATNA 25 Address of the Circle Office of the Bank located at the Centre of Examination (Offline/Online) ... and signature as per the specifications given below at point no 9.3 Candidates should ensure that both the photograph and signature are within the required specifications If the size of the file ... academic discipline other than that of the candidate The academic stream of the scribe should be different from that of the candidate iv) Both the candidate as well as the scribe will have to give...

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