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Báo cáo y học: "How biologically relevant are interaction-based modules in protein networks" ppsx

Báo cáo y học: "How biologically relevant are interaction-based modules in protein networks" ppsx

Ngày tải lên : 14/08/2014, 14:21
... then chosen Extraction of a particular modular structure Having obtained C-based and L-based modules with a B value selected as previously described, we calculated the overlap of each C-based ... horizontal white dashed lines represent the localization of modules A quick look at these figures provides evidence that proteins that are part of the same module exhibit a loosely correlated degree of ... 3(1) 6(3) Cellular organization 3(0) 6(3) Cellular environment 3(2) 1(1) Protein synthesis 3(0) 2(2) Transcription 1(1) 8(3) Cell cycle 0(0) reviews Function comment Conservation properties of module...
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Báo cáo khoa học: Distribution of the lipolysis stimulated receptor in adult and embryonic murine tissues and lethality of LSR–/– pdf

Báo cáo khoa học: Distribution of the lipolysis stimulated receptor in adult and embryonic murine tissues and lethality of LSR–/– pdf

Ngày tải lên : 16/03/2014, 18:20
... anti-LSR serum by nonimmunized or irrelevant rabbit sera In some experiments, tissues from surviving male homozygous LSR knockout mice were included as negative controls Adult mouse tissues and ... reverse: 5¢-TTGGTGGTCG AATGGGCAGGT-3¢ giving a product of 281 bp) and (forward: 5¢-GAGGATCTCGTCGTGACCCATG-3¢ and reverse: 5¢-GAGGAAGCGGTCAGCCCATT-3¢ giving a product of 179 bp) For the wild-type ... were obviously dead Interestingly homozygote embryos did not show an overall developmental delay, as shown by limb bud, eye and facial development (Fig 6A) During the last three years, no viable...
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Báo cáo y học: "Coexpression and interaction of CXCL10 and CD26 in mesenchymal cells by synergising inflammatory cytokines: CXCL8 and CXCL10 are discriminative markers for autoimmune arthropathie" doc

Báo cáo y học: "Coexpression and interaction of CXCL10 and CD26 in mesenchymal cells by synergising inflammatory cytokines: CXCL8 and CXCL10 are discriminative markers for autoimmune arthropathie" doc

Ngày tải lên : 09/08/2014, 08:22
... the synovial cavity of RA patients [25,26] In addition, synovial fibroblasts also strongly express CD26/DPP IV [27] Moreover, patients suffering from RA showed reduced serum, but not synovial fluid, ... activity Detection of dipeptidyl peptidase IV IV activity (a) Soluble dipeptidyl peptidase IV (DPP IV) activity in serum-free conditioned medium from fibroblast cultures or (b)–(d) the activity ... immunoreactivity was produced as previously shown (Figure 1) Induction of fibroblasts with IL1β or TNF-α in the presence or absence of IFN-α or IFN-β did not significantly affect membrane-bound activity...
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Báo cáo sinh học: " Exact p-value calculation for heterotypic clusters of regulatory motifs and its application in computational annotation of cis-regulatory modules" doc

Báo cáo sinh học: " Exact p-value calculation for heterotypic clusters of regulatory motifs and its application in computational annotation of cis-regulatory modules" doc

Ngày tải lên : 12/08/2014, 17:20
... identification tools, and it was observed that cooperativity-based discrimination of TFBSs surpasses the performance of models for individual TFBSs [22] On observing a cluster of TFBSs in some genome segment ... in (11) depends on K previous letters Thus, if the length |q| of the prefix q is less than K, one cannot calculate p(a) knowing only the prefix q To overcome this we divide each class Ci (r1, ... different motif positions [40] Another example of generalization is the set of words that can deviate from a consensus word for less than a given number of mismatches The most popular way to represent...
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Báo cáo y học: "omparative Efficacy and Tolerability of 5-Loxin® and Aflapin® Against Osteoarthritis of the Knee: A Double Blind, Randomized, Placebo Controlled Clinical Study"

Báo cáo y học: "omparative Efficacy and Tolerability of 5-Loxin® and Aflapin® Against Osteoarthritis of the Knee: A Double Blind, Randomized, Placebo Controlled Clinical Study"

Ngày tải lên : 25/10/2012, 11:40
... that of 5-Loxin® Aflapin exhibited better 5-lipoxygenase inhibitory activity and MMP-3 inhibition Various in vitro and In vivo studies were performed to compare efficacy of Aflapin and 5-Loxin® ... protocol was evaluated and approved by the ASRAM Institutional Review Board (IRB) An overview of the clinical study is pro- 368 vided in Figure Briefly, 186 subjects out of 283 attending the orthopaedic ... battery of preclinical studies designed in in vitro cellular models and in vivo animal models, Aflapin exhibited significantly better anti-inflammatory activities in comparison with 5-Loxin® (Data...
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Real-Time Digital Signal Processing - Chapter 5: Design and Implementation of FIR Filters

Real-Time Digital Signal Processing - Chapter 5: Design and Implementation of FIR Filters

Ngày tải lên : 23/10/2013, 22:15
... variety of areas such as audio, video, wireless communications, and medical devices For many practical applications such as wireless communications (CDMA/TDMA), streamed video (MPEG/JPEG), and voice ... or the perfect linear phase characteristic The deviation of jH…!†j from unity (0 dB) in the passband is called magnitude distortion, and the deviation from the linear phase of the phase response ... tolerance limits In the passband, the magnitude response has a peak deviation dp and in the stopband, it has a maximum deviation ds The frequencies !p and !s are the passband edge (cut-off)...
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Tài liệu Manual on the Production and Use of Live Food for Aquaculture - Phần 5 docx

Tài liệu Manual on the Production and Use of Live Food for Aquaculture - Phần 5 docx

Ngày tải lên : 15/12/2013, 00:15
... be stored for long periods without losing its viability The viability is affected when water levels are higher than 10% (start of metabolic activity) and when cysts are exposed to oxygen; i.e ... embryos Artemia females can indeed easily switch from live nauplii production (ovoviviparity) to cyst formation (oviparity) as a fast response to fluctuating circumstances Although the basic mechanisms ... (fresh product; activity normally =11-13% w/w) or bleaching powder Ca(OCl)2 (activity normally ± 70%) in the following proportions: * 0.5 g active hypochlorite product (activity normally labeled...
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iec 60364-5-54 electrical installations of buildings - selection and erection of electrical equip

iec 60364-5-54 electrical installations of buildings - selection and erection of electrical equip

Ngày tải lên : 25/12/2013, 11:03
... Electrotechnical Commission Licensed by Information Handling Services IEC 3611 P T * - 80 W 11844891 00311852 b W , Rộvision de la prộsente publication Revision of this publication Le contenu technique des ... under constant review by the I E C , thus ensuring that the content reflects current technology Les renseignements relatifs ce travail de rộvision, Iộtablissement des ộditions rộvisộes et aux ... revision, the issue of revised editions and amendment sheets may be obtained from I E C National Committees and from the following I E C sources: Bulletin de la CE1 O IECBulletin Rapport dactivitộ...
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iec 60364-5-548 electrical installations of buildings - selection and erection of electrical equi

iec 60364-5-548 electrical installations of buildings - selection and erection of electrical equi

Ngày tải lên : 25/12/2013, 11:04
... normative documents contain provisions which, through reference in this text,constituteprovisions of thissection of IEC60364.Fordatedreferences,subsequent amendments to, or revisions of, any of these ... currents via functional-earthing conductors; - protection against high d.c return currentsfunctional-earthing via conductors and protective-conductors; - equipotential bonding to provide electromagnetic ... available, advice on values shall be obtained from the equipment manufacturer 548.7.3.2 Connections for surge protection devices Earthing conductors connecting surge protection devices to the...
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Tài liệu Báo cáo khoa học: Molecular cloning and characterization of soybean protein disulfide isomerase family proteins with nonclassic active center motifs pdf

Tài liệu Báo cáo khoa học: Molecular cloning and characterization of soybean protein disulfide isomerase family proteins with nonclassic active center motifs pdf

Ngày tải lên : 18/02/2014, 11:20
... lack of enzymatic activity Mammalian PDILT, which has the same domain structure as PDI, but lacks oxidoreductase activity, has been demonstrated to have chaperone activity in vitro [34] As PDILT ... recombinant GmPDIL-3a and GmPDIL-3b Enzymatic activity assays Thiol oxidative refolding activity was assayed as previously described by measuring RNase activity produced through the regeneration of the ... refolding activity of recombinant GmPDIL-3a (3a), GmPDIL-3b (3b), GmPDIL-1 (L-1), L-1 plus 3a or 3b, GmPDIL-2 (L-2), or L-2 plus 3a or 3b Activity was assayed by measuring the RNase activity produced...
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Tài liệu Báo cáo khoa học: Peptides corresponding to helices 5 and 6 of Bax can independently form large lipid pores pdf

Tài liệu Báo cáo khoa học: Peptides corresponding to helices 5 and 6 of Bax can independently form large lipid pores pdf

Ngày tải lên : 19/02/2014, 07:20
... enhances Bax activity, and the opposite is observed for lipids with a negative intrinsic curvature [10,14,15] Similarly, small percentages of lysoPtdCho increased the activity of the previously investigated ... the behaviour is similar to that reported for the Lys-flanking variant Bax-a5KK, with small, but consistent, increases in activity in LUVs containing the nonlamellar lipid However, the activity of ... and encompassing individual helices of the characteristic a5–a6 hairpin domain can independently, and in the absence of tBid, reproduce the poration activity displayed in vitro by the concerted...
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Tài liệu Báo cáo khoa học: 1,5-Diamino-2-pentyne is both a substrate and inactivator of plant copper amine oxidases ppt

Tài liệu Báo cáo khoa học: 1,5-Diamino-2-pentyne is both a substrate and inactivator of plant copper amine oxidases ppt

Ngày tải lên : 19/02/2014, 16:20
... were each individually incubated with seven different concentrations of DAPY varying from to 50 lM at 30 °C for h Remaining activity was determined by the ratio of the measured activity of the ... maximum at 600 nm having a shoulder at 560 nm (Fig 4, lower) NADH also reacted with the reagent and provided a spectrum with a single peak centered at 510 nm DMABreacted pyrrole provided a maximum ... sativus, GPAO) and sainfoin (Onobrychis viciifolia, OVAO) seedlings were prepared in homogeneous forms following published protocols [18,19] Specific activities assayed with cadaverine as a substrate...
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Tài liệu Báo cáo khoa học: Specific targeting of a DNA-alkylating reagent to mitochondria Synthesis and characterization of [4-((11aS)-7-methoxy-1,2,3,11a-tetrahydro-5H-pyrrolo[2,1-c][1,4]benzodiazepin-5-on-8-oxy)butyl]-triphenylphosphonium iodide doc

Tài liệu Báo cáo khoa học: Specific targeting of a DNA-alkylating reagent to mitochondria Synthesis and characterization of [4-((11aS)-7-methoxy-1,2,3,11a-tetrahydro-5H-pyrrolo[2,1-c][1,4]benzodiazepin-5-on-8-oxy)butyl]-triphenylphosphonium iodide doc

Ngày tải lên : 20/02/2014, 11:20
... IgG-Oregon Green in 10% (v/v) foetal bovine serum, 0.05% (v/v) Tween 20 After washing a final five times with NaCl/Pi, the coverslips were mounted on slides and visualized using a Nikon Eclipse E800 ... and pyruvate, as these are required for the growth and survival of any q° cells that arise [51–53] After 2.5 weeks of culture ( 15 cell divisions) with mitoDC-81, clones were isolated and allowed ... still survived for several days in the presence of mitoDC-81 this would not have led to the elimination of any q° cells that arose during incubation with mitoDC-81 In summary, we found no evidence...
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Tài liệu Báo cáo khoa học: Phenol hydroxylase from Acinetobacter radioresistens S13 Isolation and characterization of the regulatory component docx

Tài liệu Báo cáo khoa học: Phenol hydroxylase from Acinetobacter radioresistens S13 Isolation and characterization of the regulatory component docx

Ngày tải lên : 21/02/2014, 00:20
... PH activity (i.e oxygen consumption promoted by the presence of phenol) Individual fractions were tested for PHR activity, using cytochrome c as substrate The fractions showing PHR activity were ... 8.5, at 30 °C Reconstitution of PH activity ‘in vitro’ Reconstitution of the complex from the purified fractions was studied by investigating the overall PH activity in the presence of variable amounts ... for the catalytic activity of the reconstituted PH system A stoichiometry PHR monomers: PHI dimer: PHO (abc) dimer was found to provide optimal phenol reaction rates PH activity in function of...
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Báo cáo khoa học: Folding and turnover of human iron regulatory protein 1 depend on its subcellular localization pdf

Báo cáo khoa học: Folding and turnover of human iron regulatory protein 1 depend on its subcellular localization pdf

Ngày tải lên : 07/03/2014, 10:20
... not known to display aconitase activity, IRP1 can assemble a [4Fe)4S] cluster to become a functional cytosolic aconitase while loosing its mRNA-binding activity The balance of IRP1 between its ... apoprotein is the main process that controls IRP1 activity as a regulator of cellular iron management [2] The importance of the aconitase activity of IRP1 in the cytosol of mammalian cells remains ... proteins of the aconitase family Results Human IRP1 displays aconitase activity in yeast mitochondria Saccharomyces cerevisiae cells harbouring the different plasmids were grown with glucose as...
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Báo cáo khoa học: Regulation of arginase II by interferon regulatory factor 3 and the involvement of polyamines in the antiviral response potx

Báo cáo khoa học: Regulation of arginase II by interferon regulatory factor 3 and the involvement of polyamines in the antiviral response potx

Ngày tải lên : 07/03/2014, 21:20
... to virus infection induces sufficient apoptosis to limit the levels of virus multiplication, thus mimicking an antiviral effect An alternative mechanism, that spermine acts by inhibition of virus ... proapoptotic and antiviral activities These results thus illustrate a potential new mechanism by which IRF-3 contributes to the development of the antiviral state IRF-3-mediated antiviral response ... infected with herpes simplex virus J Gen Virol 27, 25–33 Wang HC & Wong ML (2003) Lytic infection of pseudorabies virus in the presence of spermine, spermidine, or DFMO Virus Res 94, 121–127 Pohjanpelto...
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