... The meaning of a word reflects the reality being associated with a certain sound form There are two main types of meanings in words: lexical meaning and grammatical meaning Lexical meaning is ... important to determine word meaning in a given context 1.3.2 The Meaning of Idioms In this part, we only mention general ideas about the meaning of idioms From studying and analyzing of linguistics, ... a habit of noticing idioms in everyday situations, including reading and listening Teachers lead a discussion about figurative language including metaphors, similes, and idioms in order to show...
... confidence inhedge funds and that investors may begin to rethink their level of interest At a minimum, investors are calling into question how well directional hedge fund strategies will fare in the ... instances, the manager adds the hedge fund to his existing product portfolio, maintaining their long-only fund offering I Institutional Investment inHedge Funds: Evolving Investor Portfolio Construction ... and truly uncorrelated returns in line with the classic hedge fund alpha sought by investors in the early 2000s I Institutional Investment inHedge Funds: Evolving Investor Portfolio Construction...
... particularly in the regulated industries of financial services and internet gaming, has created a marked shortage in the supply of certain specialised skills within these industries These growing pains ... Maltese government through various initiatives including the incentivising of advancement into tertiary education and ongoing training However, besides such incentives, the government has also ... the infrastructure and regulatory demands of what needs to be in place and the increasing influence of the existing investors and perception of future investors However, one thing that has remained...
... disambiguation In Meeting of the Association for Computational Linguistics, pages 26–33 Avrim Blum and Tom Mitchell 1998 Combining labelled and unlabelled data with co-training In Proceedings of COLT’ ... by EL9 The following are not considered hedge instances: Indication of experimentally observed nonuniversal behaviour proteins with single BIR domains can also have functions in cell cycle regulation ... addressed in section 10.3 In this study we develop a learning model based around the concept of iteratively predicting labels for unlabelled training samples, the basic paradigm for both co-training...
... cues is a promising solution for addressing the false positives inhedge classifiers and for improving the portability of hedge modules 4.1 Resolving the scope of hedge keywords In this paper we ... 79.73% Plugging this model (without manual filtering) into the ICD-9 coding system as a hedge module, the ICD-9 coder http://www.inf.u-szeged.hu/∼szarvas/homepage /hedge. html 286 Results for hedge classification ... (evaluated in the Results section) which is capable of underranking irrelevant keywords in the majority of cases 2.3 Feature (or keyword) selection To handle the inherent noise in the training dataset...
... pCX-shh-IG injection (arrowheadindicated in (c) and (d), also magnified in the inlets) (C) The pCX-shh-IG-injected prostate tissue sections were stained strongly for Hedgehog protein in PIN and CaP, in ... pCXshh-IG-injected prostates (arrowhead-indicated in (b) and (c)) All luminal cells (arrowhead-indicated in (d)) and some basal cells (arrow (1)indicated in (d)) in the normal prostate expressed AR in ... arrowheadindicated in (a)) and hyperplasic basal cells (Figure 3A; arrow-indicated in (b)), P63 was detected in the cytoplasm of cells in the HGPIN (high grade PIN) lesions (Figure 3A; arrow-indicated in (c))...
... such as activating point mutations of Smo or inactivating point mutations in Ptch1 or SUFU [8-12] Although inappropriate activation of the Hh signaling pathway has been shown in many cancers, ... function(s) of IFNa in the Hh pathway In conclusion, we confirmed variable abnormalities of Hedgehog pathway activation in CML cases involved in this study, raising a possibility that combinations of ... stromally induced hedgehog signaling in B-cell malignancies Nature Medicin 2007, 13(8):944-951 14 Bai LY, Chiu CF, Lin CW, Hsu NY, Lin CL, Lo WJ, Kao MC: Differential expression of Sonic hedgehog...
... pulmonary ptc in the absence of Shh, ptc mRNA is increased in Shh-overexpressing lungs These results indicate a role for Shh signalling in pulmonary branching morphogenesis in mice In addition, ... hip (hedgehog interacting protein), a membrane glycoprotein, which seems to be a negative regulator of Hh signalling [27], and a member of SOCS (suppressor of cytokine signalling)-box WD proteins, ... Vertebrate Hedgehog signalling modulated by induction of a Hedgehog-binding protein Nature 1999, 397:617–621 reports 26 Lebeche D, Malpel S, Cardoso WV: Fibroblast growth factor interactions in the...
... would remain a significant investor in his funds for the rest of his life This concept of investing alongside clients is another trait that is indicative of the modern hedge fund Having skin in the ... discuss how and why hedge funds fit in the asset allocation picture C DEFINITION When I think of a hedge fund, I think of a private investment vehicle in which the underlying investment manager ... trading at levels comparable to GM (so an investment in DuPont was akin to buying GM and getting the DuPont business for free) He believed that the market was overvaluing GM and undervaluing...
... for Inside the House of Money from Hedge Fund Investors “Drobny has done a great job of capturing the inner workings of macro trading by interviewing some of the most interesting people in the ... herding instincts of participants sometimes push prices to extremes, explaining the prevalence of such extreme but infrequent events in reality Yra Harris (Praxis Trading) explains in his interview ... be evolving more rapidly than traditional investing institutions can manage The following chapters present the thinking of some of the best minds in the investment world about how they interpret...
... financial derivatives The staff is responsible for introducing products, consulting, convincing bank’s customers of taking derivatives’ functions in their business Moreover, with the role of intermediary ... analyzed involving to businesses as well as banks’ activities, then this chapter introduces the main effective financial instruments used to hedge risks is derivatives Derivatives are the financial instruments ... derivatives trading in Baria Vungtau province as well as Vietinbank Baria Vungtau branch in order to prove that derivatives seem be strange in forex trading in this province The main advantage of...
... have great effect on minimizing shocks in communication Therefore, a desire to have a further insight into major similarities and differences in using disjuncts as hedges has inspired the writer ... and Katz (2000), Minh (2005), Hoa (2007), and others The findings of the previous studies were mainly discussed in the light of cross-cultural perspective Yet, hedging in criticizing from pragmatic ... and Hedges in English Amsterdam/ Philadelphia: John Benjamins Publishing Company 21 Hyland, K (1998) Hedging in Scientific Research Articles Amsterdam/ Philadelphia: John Benjamins Publishing...
... protein that was shown to be asymmetrically distributed during NB mitosis in Drosophila It is a phosphotyrosine-binding domain (PTB) containing protein, which is required for the determination ... Protein phosphatase PP2A Protein phosphatase 2A PTB Phosphotyrosine binding protein ix INP Intermediate neural progenitor SOP Sensory organ precursor Lgl Giant lethal larvae Khc-73 Kinesin heavy ... timing that is indistinguishable from their wild type counterpart, despite being arrested in G2 phase throughout This result points to the existence of an intrinsic, cell cycle independent timing...
... Chapter Introduction 1.1 1.2 1.3 Origin of the Hedgehog (Hh) pathway Drosophila Hedgehog Signaling Pathway Vertebrate Hedgehog Signaling Pathway 1.3.1 Genetics in Vertebrate Models 1.3.2 The Signaling ... them, the kinesin-like protein Costal2 (Cos2), which plays an important role in controlling the transcriptional activity of the Hh pathway, remained elusive I report the cloning of a kinesin-related ... Differential Interference Contrast DIG Digoxigenin dNTP Deoxynucleoside triphosphate dpf days post fertilization DZIP1 Daz-interacting protein DZIP1-L Daz-interacting protein 1-like EDTA Ethylene diamine...
... Cells were washed again in PBS before blocking for 30 mins with 1% BSA After blocking, cells were washed again in PBS and incubated with primary antibodies diluted in PBS containing 1% BSA for 1hr ... transformed into BL21 cells and plated in LB nutrient Agar containing 50µg/ml ampicillin Single colonies were picked and inoculated overnight in 2ml LB containing 50µg/ml ampicillin 500µl from ... protein 2.16 Yeast-2-hybrid (Y2H) Y2H is a molecular technique widely used to detect protein-protein interaction In a Y2H interaction, the bait (protein of interest) is fused to the Binding Domain...
... DNA-binding proteins that interact with the enhancers of retroviruses were characterized as Core-binding factor alpha (CBFα) PEBP2 was named after the murine cDNAs polyoma enhancer-binding proteins ... Table Mechanisms of SHH signaling activation during carcinogenesis Table Mutations in the SHH signaling pathway in BCCs 10 Table Mutations in the SHH signaling pathway in medulloblastomas 14 Table ... patterning in a range of tissues during animal development It is activated by a secreted hedgehog protein of which three homologs have been identified in mammals - Sonic Hedgehog (SHH), Indian Hedgehog...
... forebrain, midbrain, hindbrain and the spinal cord This figure was reproduced from Epstein et al., 1999 2.4 SHH and neural development During the initial phase of neural induction, the ectoderm is induced ... that organize the neural tube into the forebrain, midbrain, hindbrain and spinal cord The Shh and bone morphogenetic proteins (BMP) play important roles in patterning the dorsal-ventral aspect ... also expressed in cells of the neuroectoderm lineage (Avilion et al., 2003; Eminli et al., 2008), the expression of SOX2 in ESC indicates pluripotency and a crucial factor in maintaining hESC pluripotency...