... SELF- DETERMINATION§ Introduction §Recognitionofstatehooddespitetheexistenceofanineffective government: modernstatepracticeandtheroleoftherightof self- determination§2. 1 The cases of Georgia ... introduction ofthe notion of legality in the law ofstatehoodand additional criteria for statehood§The law of self- determination§Statehoodand self- determination§Themodern law ofstatehood ... Georgia and Moldova §2. 1.1 The Republic of Georgia §2. 1 .2 The Republic of Moldova §2.2 Observations §2. 3 External self- determinationandthestatehood criterion of'government' : juridical and...
... And here's the output: Adding It All Up The JSP Files (part 2) : Attack OfThe Killer Fortune Cookies TheTheTheTheThe sum of 25 and is 30 difference of 25 and is 20 product of 25 and is 125 ... division of 25 and is remainder after division of 25 and is As with all other programming languages, division and multiplication take precedence over addition and subtraction, although parentheses can ... Try changing the values ofthe variables to match each other, and gasp in awe as the output changes In case the equals() method doesn't appeal to you, JSP offers you a choice in the form of the...
... (29 ) 345 ( 32) 33.8 26 .7 23 .2 4.5 3.4 ND Values in parentheses are the standard errors ofthe data b Values reported previously [20 ] Fig Cytotoxicity of onconase variants to K-5 62 and A-431 cell ... A chain can transport unfolded dihydrofolate reductase into the cytosol J Biol Chem 27 2, 22 097 22 1 02 22 Leland, P.A., Schultz, L.W., Kim, B.M & Raines, R.T (1998) Ribonuclease A variants with ... (Met1)-ONC (M23L) by the addition of AAP, as described in the Materials and methods Completion ofthe hydrolysis was confirmed by the disappearance ofthe (Met1)-ONC (M23L) signal in the MALDI-TOF mass...
... lg of protein) of YYY49 and YYT 42 contained approximately and ng of hHSF2, and those of YYT50 and YYT17 contained approximately 0.01 and 0.1 ng of hHSF4, as judged by the intensity of each band ... (HSP 42, HSP78, and KAR2), 3P-type HSE (APA1, HSP10, and SSA2), gap-type HSE (CPR6, CUP1, and HSP 82) , step-type HSE (FSH1, SGT2, and SSA3), and atypical HSE consisting of directly repeating nGAAn ... 3, 4, and 6), and a step-like HSE (units 2, 4, and 6); the m2 reporter gene contained a gap-like HSE (units 3, 4, and 6); the m3 reporter contained a step-like HSE (units 2, 4, and 6); the m4...
... scripts, and then run with autodock 3.0 and autogrid 3.0 [28 ,29 ] The grid parameters were the same for all three macromolecules The numbers of points in the x, y and z direction were 76, 76 and 126 , ... of HR1 and HR2, formation ofthe 6HB, and subsequent fusion ofthe host and viral membranes (Fig 4C), as supported by recent in vitro studies [ 12, 14] RC-101 binds to the HR1-binding regions of ... ligplot and hbplus were used to identify specific interactions between the ligand, RC-101 and HR2 based on proximity and atomic angles We quantified the number of interactions per HR2 residue for the...
... bands were stained with Coomassie blue For both, GST-N and GST-C34, an hCaM band is only seen in the presence of Ca2+ (lanes 5, and 9, 10) In the absence of Ca2+ (lanes 3, and 7, 8) and for the ... channels studied here share some properties of CNG channels andof KCNQ channels On the one hand they are activated by membrane depolarization 10 82 and not inactivate as KCNQ channels On the other ... hCaM-EF34 and hCaM-EF 123 4) EF-hand mutants of hCaM were also employed for functional tests on hEAG1 channels expressed in Xenopus oocytes The channel-inhibiting potency of wildtype hCaM andthe EF-hand...
... some manner of event are also contained in this category, since a manner accompanies an event The notion ofthe manner is continuous to the means since the means and manner ofan event are often ... that can hold between them T h e y are: 1) the identity and agentivity ofthe subjects in the two clauses 2) the thematic and aspectual properties ofthe event denoted by each clause 3) canonical ... 83 (22 ) 48( 12) number of agreements(c) 79 63 48 34 28 0( 92) 22 9 58(13/ 995 recall(%) c/a×lO0 89 84 75 76 100 33 i00 82 precision(%) c/b x 100 98 76 82 71 100 20 50 82 Since the combination of the...
... [Ala9]SP and [Gly9]SP on the one hand, and [b2-HAla9]SP and [HGly9]SP on the other hand Indeed, the higher pharmacological potency of [b2-HAla9]SP compared to [HGly9]SP suggests that the methyl ... FEBS 20 03 940 S Sagan et al (Eur J Biochem 27 0) Fig Schematic representation of a-, b2- and b3-amino acids with the torsion angles /, h and w For the b2 and b3-amino acid substituted-SP analogues, ... substance P antagonists substituted with 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 b-phenyl- or b-benzyl-proline at the position 10 Eur J Pharmacol 25 8, 27 3 27 6 Sagan, S., Beaujouan J.-C.,...
... coordinates the back˚ bone N and O of Lys–5 (2. 81, 2. 65 A) and also supports orientation of Arg 823 Finally, Asn830 ˚ coordinates Oe1 of Glu+1 (2. 65 A) (Fig 2C) and this moves aG towards the substrate ... movement) andthe N-terminal part ofthe substrate has moved out ofthe kinase subsite delineated by residues Arg7 12 andthe region including residues Arg 823 –Asn830 The side chain of Lys785 in the ... synthesized to probe the relevance ofthe+2 substrate position in affinity and turnover efficiency By contrast to data from the in vitro peptide screen, the effect of changing the substrate +2...
... shells of C108 (2. 5 lg; Fig 5, lanes and 5), Nd-sD (20 0 lg; Fig 5, lanes and 6) and two transgenic lines [L6 · (5 lg; Fig 5, lanes and 7) and H-chain L-chain fhx /25 H-chain : L-chain : fhx/P25 L7-4 ... and 125 ng for fhx/P25 from cocoons of C108 andthe transgenic line L6 · 7, or lg for H-chain, 10 lg for L-chain and 100 lg for fhx/P25 from naked-pupa cocoons of Nd-sD and cocoons ofthe transgenic ... 3A, lane 3) or in cocoons (Fig 3A, lane 1) The 30-kDa fhx/P25 was converted to the 27 -kDa single band by digestion with the bacterial a1 ,2- mannosidase (Fig 3A, lanes 4–6), andthe 30- and 27 -kDa...
... mutants (Q162A, Q162L, and Q162E) lost iloprost-binding activity (Figs 2Ab and 6Bb) shows the importance ofthe identity ofthe residue for ligand recognition, and furthermore indicates that the residues ... thromboxane A2 receptor and analysis ofthe receptor-ligand interaction J Med Chem 36, 820 – 825 21 Ruan KH, Wu J, So SP, Jenkins LA & Ruan CH (20 04) NMR structure ofthe thromboxane A2 receptor ligand recognition ... actions of PGI2 and TXA2, it is important to understand the molecular mechanism by which IP and TP selectively recognize ligand molecules on the extracellular side of their membrane, transfer them...
... 10, mixture of A2¢p5¢A and A2¢p5¢A2¢p5¢A2¢p5¢A; 11, mixture of A2¢p5¢A2¢p5¢A and A3¢p5¢A2¢p5¢A (m ⁄ z 924 .6); 12, A2¢p5¢A3¢p5¢A (m ⁄ z 924 .7); 13, putative A2¢p5¢A2¢p5¢A3¢p5¢A (m ⁄ z 125 3.9); 14, ... most distant from humans The general significance ofthe study of 2- 5A synthetase as one ofthe key components ofthe mammalian 2- 5A system will be its contribution to our understanding ofthe evolution ... procedures ofthe porcine 2- 5A synthetase (data not shown) Figure demonstrates the results ofthe purification ofthe recombinant proteins The occurrence of dominant bands ofthe recombinant proteins...
... signi®cantly in size from the structurally equivalent residues in PYP and HERG, again favoring the heme binding These are glycines 22 4 and 25 1 that substitute Phe96 and Val 120 in PYP, and Phe98 and ... Additional AhR residues involved in ligand recognitionand discrimination are Arg2 82 and Gln377 close to the polar end ofthe ligand inside the pocket TCDD and heme cofactor atoms are colored green ... interaction and docking calculations to more accurately de®ne the orientation ofthe ligand in the binding cavity ACKNOWLEDGEMENTS The ®nancial support by the Italian CNR (grant no 98.0 324 5.ST74) and the...
... 13 26 29 15 Target 18 36 40 92 Lit FB 76 36 19 60 641 Nonlit FB 58 1 72 720 miss pass rest ride roll Lit Target 58 22 25 Nonlit Target 40 20 26 46 Target 98 28 48 71 Lit FB 23 6 1443 42 221 1 32 ... basic prin1 The girl and her brother grasped their mother’s hand He thinks he has grasped the essentials ofthe institute’s ciples The first is that the contents ofthe DoKfinance philosophies MIE ... (Cohen) and κ (S&C) on a random sample of 20 0 annotated examples annotated by two different annotators was found to be 0.77 As per ((Di Eugenio & Glass, 20 04), cf refs therein), the standard assessment...
... tures of "Beans" and which provides a semantic role for it The only connection between "know" and "Beans" is that the finite verb allows the extraction of "Beans", thus defining ... parsing according to the slot and filler principle In Proc ofthe 12 th Int Conf on Computational Linguistics Budapest, HU, 22 27Aug 1988, Vol 1, pp 24 2 -24 4 Hepple, M (1990) Word order and obliqueness ... descriptional dimensions The separation of dominance and precedence presented here grew out of our work on German, and retains the local flavor of dependency specification, while at the same time covering...
... al., 20 08) We also made a manual verification ofthe quality ofthe contributions, and checked by hand the quality of all the contributions With two exceptions – two entries where the true and ... detachment from theselfand vocabulary that emphasizes certainty In future work, we plan to explore therole played by affect andthe possible integration of automatic emotion analysis into therecognition ... as the ratio between the coverage ofthe class in the corpus D with respect to the coverage ofthe same class in the corpus T : To gain further insight into the variation of accuracy with the...
... council of all the lords of his realm at Westminster; and there he put to them this demand, and prayed and besought them of their goodness, andof their good counsel and good-will, as touching theright ... other unfortunate inhabitants of Lisbon, and seem to have lost their all in the earthquake In their distress they cast their eyes to the land of their fathers, and applied for the charity of their ... the privileges and authority ofthe high admiral, the Duke of Exeter. [21 ] The following year, in the summer, he was made lieutenant and guardian-general of all Normandy; and in the December of...