... proteases of
the coagulation system including thrombin (factor
IIa) and factors IXa, Xa, XIa and XIIa. The princi-
pal targets of the serpin are usually regarded as being
thrombin and factor Xa, although ... immediate and medium term future.
Acknowledgements
This work was supported by the National Health &
Medical Research Council of Australia, the Austra-
lian Research Council, the National Heart ... thrombin anion-binding
exosite-1 is a primary part of the allosteric activation
mechanism.
For many years, the physiological activator of HC-II
has been assumed to be extravascular dermatan sulfate
[56–64],...
... lit by candles and
draped with gathered curtains that turned the walls into the proscenia of
a grand and ancient stage. There were four or five small tables and a
long one at the back of the room, ... the neat stitching that ran the bind-
ing and the spine, holding together the nylon and the denim, taken from
a pair of jeans, a backpack. The end-papers were yellowed page three
girls fromthe ... he'd joined the Order, and
she wasn't there anymore. Her numbers all rang dead.
The apartment building had once been a pleasant, middle-class sort of
place, witha red awning and a niche...
... Tawara H, Nakazawa H, Sumida M, Matsubara
F, Aoyama S, Iritani Y, Hayashi Y, Kamogawa K.
Expression of the Newcastle disease virus (NDV) fusion
glycoprotein and vaccination against NDV challenge ... Iritani Y, Aoyama S, Takigami S, Hayashi Y, Ogawa R,
Yanagida N, Saeki S, Kamogawa K. Antibody response to
Newcastle disease virus (NDV) of recombinant fowlpox
virus (FPV) expressing a hemagglutinin-neuraminidase ... clinical signs
and mortality. The re-isolation of the challenge virus was
carried out in CEF cells withthe oropharyngeal and cloacal
swab samples 5 day after the challenge infection. All
chickens...
... Students have come from 23 countries,
mainly in Africa, withthe largest numbers from Nigeria,
Tanzania and Uganda. Seventy-four were male and 43
female; their previous education and current occupation
are ... in
discussions with various organizations about accredita-
tion, but at present the awards are made solely by the Peo-
ples Open Access Education Initiative. Credibility of the
awards may depend on our ability ... [8].
Results
Administrative infrastructure
A group of colleagues, known to the author and instigator
(RFH), came together to help plan the initiative. After the
creation of a charitable trust in the United...
... de-
mand, these Group companies are
developing major expansion plans.
Considerable progress has already
been made at St. Lawrence for two
slag grinding plants in the United
States and Canada respectively ... integrated in North America’s
NAFTA, which boosted growth. At
the same time greater stability was
achieved. Having shaken off the turbu-
lence dogging the international finan-
cial markets, Central ... year.
Dr. h.c. Thomas Schmidheiny
Chairman and Managing Director
The half-year result was again very favorable and under-
scored the strength of the Group in the face of rapidly
changing market conditions....
... Then go
back and try that approach withthe original problem.
Ask if the student can make an estimate of the answer. If the answer is a number,
about how big is it? Bigger or smaller than ...
understand the mathematical concepts
Lauren Richetti, an IMP 4 student, presents a graph
How to HelpWith Math Homework When The Answers Aren’t in the Book
How to HelpWith Homework
As you may ...
Pamphlet layout and design by Jeremiah Beaudry and William Blatner
Photos by William Blatner and Jackie Rigali
How to HelpWith Math Homework When The Answers Aren’t in the Book
There’s...
... PALMER AT THE AGE OF 75.
CHAPTER V.
[Pg 45]
APPRECIATIONS OF RALPH ALLEN, JOHN PALMER, AND SIR FRANCIS
FREELING, MAIL AND COACH ADMINISTRATORS.
On the 25th April, 1901, the day after a ... Street.
The Gloucester and Aberystwith mail-coach continued to run until the year 1854, and
it is believed that was the last regular main road mail-coach which was kept on the
road. Its guard from ... lamented far beyond the circle of her own
family, extensive as it is. The amiableness of her manner and the rational
giving such an accommodation to the city of Bath as he always hoped that plan...
... DNA lesions depends on the capacity of
the cell to repair the damage before it can be incorporated
permanently into the genome. Typically, DNA damage is
repaired at a relative high rate in human ... survival) after irradiation. The in vivo
biological activity was assayed by the ability to prevent UV
induced erythema of human skin. After informed consent
and approval fromthe Ethical Committee ... cyanobacteria,
corals and other marine organisms are much more
advanced than those of mammals because photosynthetic
organisms depend on solar irradiation as their primary
source of energy, and at the same time...
... collec-
tion and refinement are summarized in Table 1. The
program procheck [34] was used to analyse conforma-
tional variations fromthe defined norms, with the
quality of the Ramachandran plots [35] ... To accommodate
K100 as a ligand a number of main-chain atoms are
displaced relative to their positions in the wt structure.
Although backbone deviations are detected at the start
of the ligand ... the rearrangement of the ‘open’ and
‘closed’ forms of the ligand loop [19]. Therefore, con-
former A may be considered as the open form, albeit
with the axial ligand still intact, withthe main-...
... in the databases. The two proteins migrating
at 50 and 55 kDa (bands A and B; Fig. 1A) were
identified from their N-terminal sequences as similar to
a- amylase (accession no. AAA17751) from ... and
analysed by SDS/PAGE.
Carboxypeptidase assays and expression
of HaCA42 mRNA
Carboxypeptidase assays using the synthetic substrates
furylacryloyl-Phe-Phe (FAPP), furylacryloyl-Ala-Lys
(FAAK) ... enzyme was
analysed by SDS/PAGE (data not shown). By analogy with
the activation of mammalian carboxypeptidases, these
polypeptides correspond to the active HaCa42 carboxy-
peptidase (36 kDa polypeptide)...
... of all the b Na-ScTxs from all
the a Na-ScTxs. Thea Na-ScTxs have identities of the order
of 50% among themselves, the same being true for all the
b Na-ScTxs (data not shown). However, when the ... constraints were
added to the calculations. The dynamic annealing struc-
ture calculations were performed withthe CNS software
suite [44].
Analysis of Na
+
-channel sequences
By searching data banks ... than the cardiac isoform rNa
V
1.5
[67]). However, when the overall charge of both the toxins
and the channels are considered together, a plausible
explanation comes from analysis of the other region
involved...
... human
fibrosarcoma and MCF 7 from human breast adenocarci-
noma, were obtained fromthe Istituto Zooprofilattico
Sperimentale della Lombardia e dell’Emilia, Brescia, Italy.
Lipids. A series of natural and ... LUVs.
Similar aggregates appeared only very faintly in the absence
of lipids (Fig. 4A) . The rather long lag phase preceding fast
hemolysis (Fig. 1A) may also indicate that the formation of
a functional ... by the mushroom Agrocybe aegerita [3,4].
Moreover, 13 of the ESTs, if translated, are identical with a
138-amino-acid protein (PriA) translated from P. ostreatus
cDNA (EMBL/GenBank/DDBJ databases:...
... 5Â-CTCCG
AGCTCTCATGGCAGTTTAAC-3Â (reverse) and 5Â-ATA
CCATGGAACAGCCAGAGTATAAAG-3Â (forward), 5 Â-
AGG
GAGCTCTCAGAATAACTTCTCTGTA-3Â (reverse),
respectively, were designed (restriction sites are underlined).
Genomic ... membrane A
0
domain,
involved in ion translocation [2–4]. The primary struc-
ture of the archaeal ATP synthase is similar to that of
the eukaryotic V-ATPase, but its function as an ATP
synthase ... transmitted
to the membrane-bound A
0
domain. Energy coupling
between the two active domains occurs via the so-
called stalk part(s) [5].
Keywords
A
1
A
0
ATP synthase; archaeal ATPase; F
1
F
0
ATP synthase;...
... Universidad Nacional de Asunción. Río de la
Plata y Lagerenza, Asunción (2511), Paraguay
Email: Gabriel I Parra* - gabriel_parra@hotmail.com; Emilio E Espinola - emilioespinola@hotmail.com
* ... Corresponding author
Abstract
In recent years it was reported that the accumulation of point mutations in VP4 and VP7 genes of
rotavirus strains was the main cause of the failure of the G or P-typing. Failures ... be
typed because the 3' end of the primer binding site had a
perfect match.
In order to evaluate how many G1 strains included in the
GenBank database have these four specific mismatches
and its...
... TG-3' (antisense), and 5'-AAT GGG AGG
AGC TTC CAG AG-3' (sense) and 5'-ACC AAC CCC ATA
TTC AGC AG-3' (antisense). To ensure equivalent loading,
glyceraldehyde-3-phosphate ... osteoblasts was
extracted with TRIzol™ reagent (Invitrogen, Burlington,
Ontario, Canada) in accordance withthe manufacturer's spec-
ifications and than treated withthe DNA-free™ DNase Treat-
ment ... dehydrogenase (GAPDH) was
amplified in the same solution, withthe use of 20 pmol of each
primer 5'-CAG AAC ATC ATC CCT GCC TCT-3' (sense) and
5'-GCT TGA CAA AGT GGT CGT TGAG-3' (antisense)...