with a little help from my friends sang by the beatles lyrics

Tài liệu Báo cáo khoa học: Control of the coagulation system by serpins Getting by with a little help from glycosaminoglycans pptx

Tài liệu Báo cáo khoa học: Control of the coagulation system by serpins Getting by with a little help from glycosaminoglycans pptx

Ngày tải lên : 20/02/2014, 02:21
... proteases of the coagulation system including thrombin (factor IIa) and factors IXa, Xa, XIa and XIIa. The princi- pal targets of the serpin are usually regarded as being thrombin and factor Xa, although ... immediate and medium term future. Acknowledgements This work was supported by the National Health & Medical Research Council of Australia, the Austra- lian Research Council, the National Heart ... bond cleavage appears to be arrested at the acyl intermediate by the unique action of the serpin, whereby the RCL of the serpin inserts into the major A b -sheet causing the protease to be rapidly...
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With a Little Help pptx

With a Little Help pptx

Ngày tải lên : 06/03/2014, 14:20
... lit by candles and draped with gathered curtains that turned the walls into the proscenia of a grand and ancient stage. There were four or five small tables and a long one at the back of the ... either," said a voice at his side. I used to change for the F Train there every day when I was a kid." It was a woman, about the same age as Gerta, but more beaten down by the years, ... the neat stitching that ran the bind- ing and the spine, holding together the nylon and the denim, taken from a pair of jeans, a backpack. The end-papers were yellowed page three girls from the...
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Preliminary organic compound analysis of microparticles returned from Asteroid 25143 Itokawa by the Hayabusa mission pot

Preliminary organic compound analysis of microparticles returned from Asteroid 25143 Itokawa by the Hayabusa mission pot

Ngày tải lên : 28/03/2014, 20:20
... (1979) Amino acids in the Yamato carbonaceous chondrite from Antarc- tica. Nature 282, 1183–1186. Shimoyama, A. , Harada, K. and Yanai, K. (1985) Amino acids from the Yamato-791198 carbonaceous ... study, the abun- dance of Gly, L,D-Ala, AIB, and L,D-isovaline (Isoval) is examined, because Gly and Ala are abundant amino acids in most extraterrestrial materials, and AIB and Isoval are free ... from Itokawa 69 Fig. 6. Mass spectra of negative ions in ToF-SIMS analysis. a) Hayabusa particles extract, and b) blank extract. 64 H. Naraoka et al. material analyses (Fig. 1). The -0017 particle...
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Tài liệu Gynecological cancer patients’ differentiated use of help from a nurse navigator: a qualitative study ppt

Tài liệu Gynecological cancer patients’ differentiated use of help from a nurse navigator: a qualitative study ppt

Ngày tải lên : 13/02/2014, 06:20
... the NN – they had another better help before the NN contacted them. The NN took the primary contact to the female patients and offered help in the early part of a cancer trajectory. The NN was ... what kind of add- itional help the patients should have. Navigators in cancer care have been proposed to embrace this extra help. They help the cancer patient “not only travel the healthcare maze ... I have heard nothing. I find that scary. (At discharge) Doctors . come and go as they see fit . they come and say their bit and then they leave again (ye s) they can go as far as to turn their...
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Tài liệu Báo cáo Y học: Caged O2 Reaction of cytochrome bo3 oxidase with photochemically released dioxygen from a cobalt peroxo complex doc

Tài liệu Báo cáo Y học: Caged O2 Reaction of cytochrome bo3 oxidase with photochemically released dioxygen from a cobalt peroxo complex doc

Ngày tải lên : 21/02/2014, 15:20
... oxidase from Paracoccus denitrificans. Nature 376, 660–669. 8. Tsukihara, T., Aoyama, H., Yamashita, E., Tomizaki, T., Yamaguchi, H., Shinzawa-Itoh, K., Nakashima, R., Yaono, R. & Yoshikawa, ... sealed with another CaF 2 plate, and placed into a metallic sample holder. The following cuvette handling was carried out in the aerobic atmosphere. The absorbance spectra of the mixture before and ... sample containment, maintained at 4 °C, was purged with dry air to minimize absorbance by water vapor. A water-cooled globar was used as source of radiation, which was measured by a nitrogen-cooled...
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Báo cáo khoa học: Molecular design of a nylon-6 byproduct-degrading enzyme from a carboxylesterase with a b-lactamase fold ppt

Báo cáo khoa học: Molecular design of a nylon-6 byproduct-degrading enzyme from a carboxylesterase with a b-lactamase fold ppt

Ngày tải lên : 07/03/2014, 00:20
... 489–495. 4 Kinoshita S, Terada T, Taniguchi T, Takene Y, Masu- da S, Matsunaga N & Okada H (1981) Purification and characterization of 6-aminohexanoic acid oligomer hydrolase of Flavobacterium sp. ... S & Higuchi Y (2005) Crystallization and x-ray diffrac- tion analysis of 6-aminohexanoate-dimer hydrolase from Arthrobacter sp. KI72. Acta Crystallogr F61, 928–930. 15 Hatanaka HS, Fujiyama ... potentially possesses an advantage for biotechnological applications. X-ray crystallographic analyses of the G181D ⁄ H266N ⁄ D370Y enzyme and the inactive S11 2A- mutant–Ald complex revealed that Ald...
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Báo cáo khoa học: A novel antifungal hevein-type peptide from Triticum kiharae seeds with a unique 10-cysteine motif doc

Báo cáo khoa học: A novel antifungal hevein-type peptide from Triticum kiharae seeds with a unique 10-cysteine motif doc

Ngày tải lên : 07/03/2014, 02:20
... CAGGCTCGTGGTGCTAAATGCCCGAACTGCCTGTGCTGTG 3f GTAAGTACGGCTTCTGCGGTTCTGGTGACGCTTACTGTGG 4f CGCTGGTTCTTGCCAGTCTCAGTGCCGTGGTTGCTAG GGAT 1r TTTAGCACCACGAGCCTGGTCACCGCAACGCTGAGC 2r CGCAGAAGCCGTACTTACCACAGCACAGGCAGTTCG 3r ... CGCAGAAGCCGTACTTACCACAGCACAGGCAGTTCG 3r GACTGGCAAGAACCAGCGCCACAGTAAGCGTCACCA Reverse GCTA GGATCCCTAGCAACCACGGCAC Table 2. Antifungal activity of WAMP- 1a. IC 50 is the concentration necessary for 50% growth inhibition. Fungi ... Escherichia coli and assays of recombinant WAMP- 1a activity against diverse plant pathogens, such as chitin-containing and chitin-free fungi, and Gram- positive and Gram-negative bacteria. The amino acid sequence...
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Báo cáo khóa học: A new UV-B absorbing mycosporine with photo protective activity from the lichenized ascomycete Collema cristatum docx

Báo cáo khóa học: A new UV-B absorbing mycosporine with photo protective activity from the lichenized ascomycete Collema cristatum docx

Ngày tải lên : 07/03/2014, 15:20
... survival) after irradiation. The in vivo biological activity was assayed by the ability to prevent UV induced erythema of human skin. After informed consent and approval from the Ethical Committee ... DNA lesions depends on the capacity of the cell to repair the damage before it can be incorporated permanently into the genome. Typically, DNA damage is repaired at a relative high rate in human ... cyanobacteria, corals and other marine organisms are much more advanced than those of mammals because photosynthetic organisms depend on solar irradiation as their primary source of energy, and at the same time...
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Báo cáo khoa học: The effect of replacing the axial methionine ligand with a lysine residue in cytochrome c-550 from Paracoccus versutus assessed by X-ray crystallography and unfolding ppt

Báo cáo khoa học: The effect of replacing the axial methionine ligand with a lysine residue in cytochrome c-550 from Paracoccus versutus assessed by X-ray crystallography and unfolding ppt

Ngày tải lên : 07/03/2014, 17:20
... collec- tion and refinement are summarized in Table 1. The program procheck [34] was used to analyse conforma- tional variations from the defined norms, with the quality of the Ramachandran plots [35] ... to the fact that in the latter the absence of coordination by the Met does not impose any conformational constraints and the locali- zed region of the loop affected by release of the Met ligand ... To accommodate K100 as a ligand a number of main-chain atoms are displaced relative to their positions in the wt structure. Although backbone deviations are detected at the start of the ligand...
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Báo cáo khoa học: Characterization of a digestive carboxypeptidase from the insect pest corn earworm (Helicoverpa armigera) with novel specificity towards C-terminal glutamate residues pptx

Báo cáo khoa học: Characterization of a digestive carboxypeptidase from the insect pest corn earworm (Helicoverpa armigera) with novel specificity towards C-terminal glutamate residues pptx

Ngày tải lên : 23/03/2014, 12:20
... and analysed by SDS/PAGE. Carboxypeptidase assays and expression of HaCA42 mRNA Carboxypeptidase assays using the synthetic substrates furylacryloyl-Phe-Phe (FAPP), furylacryloyl-Ala-Lys (FAAK) ... enzyme was analysed by SDS/PAGE (data not shown). By analogy with the activation of mammalian carboxypeptidases, these polypeptides correspond to the active HaCa42 carboxy- peptidase (36 kDa polypeptide) ... in the databases. The two proteins migrating at  50 and  55 kDa (bands A and B; Fig. 1A) were identified from their N-terminal sequences as similar to a- amylase (accession no. AAA17751) from...
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Báo cáo khoa học: NMR solution structure of Cn12, a novel peptide from the Mexican scorpion Centruroides noxius with a typical b-toxin sequence but with a-like physiological activity doc

Báo cáo khoa học: NMR solution structure of Cn12, a novel peptide from the Mexican scorpion Centruroides noxius with a typical b-toxin sequence but with a-like physiological activity doc

Ngày tải lên : 23/03/2014, 12:20
... of all the b Na-ScTxs from all the a Na-ScTxs. The a Na-ScTxs have identities of the order of 50% among themselves, the same being true for all the b Na-ScTxs (data not shown). However, when the ... constraints were added to the calculations. The dynamic annealing struc- ture calculations were performed with the CNS software suite [44]. Analysis of Na + -channel sequences By searching data banks ... 7.30. Patch-clamp recordings and data analysis. The currents were recorded by means of the patch-clamp amplifier MultiClamp 70 0A (Axon Instruments, Foster City, CA, USA) at room temperature as previously...
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Báo cáo khoa học: Antimicrobial peptides from hylid and ranin frogs originated from a 150-million-year-old ancestral precursor with a conserved signal peptide but a hypermutable antimicrobial domain pot

Báo cáo khoa học: Antimicrobial peptides from hylid and ranin frogs originated from a 150-million-year-old ancestral precursor with a conserved signal peptide but a hypermutable antimicrobial domain pot

Ngày tải lên : 23/03/2014, 17:21
... GWMSKIASGIGTFLSGMQQa DRS B1 AMWKDVLKKIGTVALHAGKAALGAVADTISQa DRS B2 GLWSKIKEVGKEAAKAAAKAAGKAALGAVSEAVa DRS B3 ALWKNMLKGIGKLAGQAALGAVKTLVGAE DRS B4 ALWKDILKNVGKAAGKAVLNTVTDMVNQa DRS B6 ALWKDILKNAGKAALNEINQLVNQa PBN2 ... 5Â-AGCATAACTGGAACGTGGG-3Â for caerin 1.12, 5Â-CAGCAATAAGTGGAACAACG-3Â for caerin 1.13, 5Â-GTGTTTAGCAACGGATTTACC-3Â for caerin 1.14 and 5Â-AGCAACGGATCCTAGGA CAC-3Â for caerin 1.15. The temperature ... isolated India between 150 and 65 Ma and colonized the Laurasian land mass after India collided with Asia. Abbreviations; AF, Africa; IND, India; AUS, Australia; SA, South America; ANT, Antartica....
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Báo cáo khoa học: Interaction of ostreolysin, a cytolytic protein from the edible mushroom Pleurotus ostreatus, with lipid membranes and modulation by lysophospholipids pptx

Báo cáo khoa học: Interaction of ostreolysin, a cytolytic protein from the edible mushroom Pleurotus ostreatus, with lipid membranes and modulation by lysophospholipids pptx

Ngày tải lên : 23/03/2014, 21:20
... LUVs. Similar aggregates appeared only very faintly in the absence of lipids (Fig. 4A) . The rather long lag phase preceding fast hemolysis (Fig. 1A) may also indicate that the formation of a functional ... initiation by the mushroom Agrocybe aegerita [3,4]. Moreover, 13 of the ESTs, if translated, are identical with a 138-amino-acid protein (PriA) translated from P. ostreatus cDNA (EMBL/GenBank/DDBJ databases: ... activity at nanomolar concentrations. Searches in the nucleotide and protein databases revealed that the sequence of the ostreolysin N-terminal 50 amino acids was 88% identical with the putative PriA...
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Báo cáo khoa học: Identification of critical residues of subunit H in its interaction with subunit E of the A-ATP synthase from Methanocaldococcus jannaschii potx

Báo cáo khoa học: Identification of critical residues of subunit H in its interaction with subunit E of the A-ATP synthase from Methanocaldococcus jannaschii potx

Ngày tải lên : 30/03/2014, 04:20
... and E101–206), the primers 5Â-GTTG CCA TGGCTGTGAAATTGATGGGA-3Â (forward), 5Â-CTCCG AGCTCTCATGGCAGTTTAAC-3Â (reverse) and 5Â-ATA CCATGGAACAGCCAGAGTATAAAG-3Â (forward), 5 Â- AGG GAGCTCTCAGAATAACTTCTCTGTA-3Â ... pos- sesses a water-soluble A 1 domain, containing the cata- lytic sites, and an integral membrane A 0 domain, involved in ion translocation [2–4]. The primary struc- ture of the archaeal ATP synthase ... association was obtained by titration studies using the N-terminal peptides E1–20, E21–40 and E41–60. These data indicate that the N-terminal tail E41–60 interacts with the N-terminal amino acids...
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