which catalyzes the oxidative deamination of lglutamate
Báo cáo khoa học: The oxidative effect of bacterial lipopolysaccharide on native and cross-linked human hemoglobin as a function of the structure of the lipopolysaccharide A comparison of the effects of smooth and rough lipopolysaccharide ppt
Ngày tải lên :
08/03/2014, 10:20
... minne-
sota. In the presence of EDTA, the oxidative effect of the
rough E. coli LPS approaches that of the smooth S. min-
nesota LPS.
The results of experiments, in which the oxidation of
Hb A
0
by the four ... measure
of the rate of oxidation of oxyHb.
RESULTS
The effect of pH on the auto-oxidation of cross-linked Hb
was studied. The rate of decrease of the concentration of
oxyHb increased as the pH ... rates of oxidation
caused by each of the LPSs studied should be similar to each
other, i.e. simply that of the rate of oxidation of dimers.
The increase in rate of oxidation in the presence of rough
E....
- 6
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- 0
Tài liệu Báo cáo khoa học: The Arabidopsis protein kinase Pto-interacting 1-4 is a common target of the oxidative signal-inducible 1 and mitogen-activated protein kinases docx
Ngày tải lên :
14/02/2014, 19:20
... forms of the
MAPKs were produced as GST-lofMPK3 and GST-
lofMPK6. However, when lofMPK3 and lofMPK6
proteins were tested for phosphorylation with OXI1,
no phosphorylation of lofMPK3 or lofMPK6 ... pathogen attack.
The Arabidopsis genome encodes 39 AGC kinases,
of which 23 are classified to the AGC VIII group [8,9].
The AGC kinases were named on the basis of their
homology to the mammalian ... front of the GUS gene. For PTI1-4, a 1.8 Kb
region upstream of the PTI1-4 (At2g47060) translational
start was subcloned EcoRI-XhoI.
The 2.2 Kb OXI1 promoter and the genomic sequence of
OXI1 with the...
- 11
- 700
- 0
Tài liệu Báo cáo khoa học: Nucleolin/C23 mediates the antiapoptotic effect of heat shock protein 70 during oxidative stress pptx
Ngày tải lên :
16/02/2014, 09:20
... the relationship of these two molecules is still
largely unknown. The aim of the current study was to investigate the
potential involvement of nucleolin ⁄ C23 in the antiapoptotic mechanism of
Hsp70. ... and fragmentation of their
nuclei. The percentage of apoptotic cells was calculated as
the number of apoptotic cells divided by the total number
of cells counted. A minimum of 500 cells were ... by
the antisense oligonucleotide, the protection of
Hsp70 is lost.
Taken together, our results demonstrate an impor-
tant relationship among the regulation of nucleo-
lin ⁄ C23, the activation of...
- 11
- 614
- 0
Tài liệu Báo cáo khoa học: A novel coupled enzyme assay reveals an enzyme responsible for the deamination of a chemically unstable intermediate in the metabolic pathway of 4-amino-3-hydroxybenzoic acid inBordetellasp. strain 10d doc
Ngày tải lên :
19/02/2014, 16:20
... analysis, and the
determination of released ammonia. The coupled enzyme
assay revealed the mechanism of the deamination reaction
and the subsequent metabolism, including the deamination
step.
The product ... [10]. The enzyme catalyzes the ring fission of
4-amino-3-hydroxybenzoic acid to form 2-amino-5-carb-
oxymuconic 6-semialdehyde (Fig. 1A). The cloning and
nucleotide sequence of the gene encoding the ... doi:10.1111/j.1432-1033.2004.04258.x
present in cell extracts of succinate/glucose-grown cells;
therefore, the s ynthesis of the e nzyme was indu cible. Table 1
shows a summary of a typical enzyme purification. The
enzyme was purified...
- 7
- 613
- 1
Tài liệu Báo cáo khoa học: Models and mechanisms of O-O bond activation by cytochrome P450 A critical assessment of the potential role of multiple active intermediates in oxidative catalysis doc
Ngày tải lên :
19/02/2014, 16:20
... chame-
leons, in which small alterations in the environment can
cause drastic changes in the reactivity of the active species
[76]. Further support in favour of th e idea of the involve-
ment of a high-valent ... intermediate [11]. The sum of
these findings points at the involvement of more than one
active oxidant in the diverse types of P450-catalyzed
substrate processing [12–15].
The g oal of t he p resent ... vis-a
`
-vis the TSR the ory . On the
other h and, intractability of h igh-energy intermediates such
as ferryl precludes facile experimental proof of the Ôtwo-
stateÕ proposal owing to l ack of a ppropriate...
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- 0
Tài liệu Báo cáo khoa học: Proton transfer in the oxidative half-reaction of pentaerythritol tetranitrate reductase Structure of the reduced enzyme-progesterone complex and the roles of residues Tyr186, His181 and His184 pdf
Ngày tải lên :
20/02/2014, 02:21
... productive binding of steroid substrates:
in the first, a (small) sub population of enzyme binds
directly the steroid in the reactive conformation, with
the remainder of the enzyme binding the unreactive
conformation. ... grossly perturb the
overall framework of the enzyme or the active site. The active sites
of the enzymes are shown in stick format with the sigmaA weigh-
ted 2F
0
-F
c
density for the Y186F mutant ... bond in
close proximity of the N5 atom. A putative flipping
motion of the progesterone molecule along an axis
parallel to the FMN plane aligns the C1-C2 with the
plane of the isoalloxazine ring...
- 12
- 603
- 0
Báo cáo khoa học: Oxidative stress is involved in the permeabilization of the inner membrane of brain mitochondria exposed to hypoxia/reoxygenation and low micromolar Ca2+ Lorenz Schild1 and Georg Reiser2 doc
Ngày tải lên :
16/03/2014, 22:20
... An
additional source of superoxide anion radicals is com-
plex I [14]. The degree of production of ROS by the
respiratory chain depends on the type of tissue, the
kind of substrates driving oxidative phosphorylation
(either ... pmolÆ
s
)1
Æmg
)1
of mitochondrial protein. The decrease in the
fluorescence signal recorded at the moment of reoxy-
genation is caused by dilution due to the addition of
1 mL medium.
To investigate whether the ... permeabilization of the
membrane system. Even in the additional presence
of 10 mm TEMPOL, significant permeabilization of
the mitochondrial membrane occurred, which was
shown by the NADH sensitivity of state...
- 9
- 433
- 0
Báo cáo khoa học: Detection and characterization of a novel extracellular fungal enzyme that catalyzes the specific and hydrolytic cleavage of lignin guaiacylglycerol b-aryl ether linkages pdf
Ngày tải lên :
17/03/2014, 03:20
... oxygen affects the formation of the
quinonemethide. Then, water attacks the Ca position in
the quinonemethide and the b-aryl ether linkage is cleaved.
Another water molecule then attacks the Ca position ... Analysis of the products of the reaction
revealed the presence of guaiacylglycerol (GG) and 4MU
(data not shown).
Localization of enzymatic activity
To confirm the localization of the b-aryl ether ... 6).
To clarify the substrate specificity of the b-aryl ether
cleavage enzyme, we synthesized the substrates GOUbz
Fig. 7. Substrate specify of the b-aryl ether
cleavage activity of 2BW-1. Structure...
- 10
- 670
- 0
Báo cáo khoa học: The crystal structure of annexin Gh1 from Gossypium hirsutum reveals an unusual S3 cluster Implications for cellulose synthase complex formation and oxidative stress response potx
Ngày tải lên :
17/03/2014, 03:20
... either distorted or the access of a
cation to the site is blocked by the p resence of a side chain
of a b asic residue. I n case of the IIAB s ite (Fig. 2), the
acidic re sidue a cting a s the ... sites in the first domain.
The observed conformation of the other domains does not
allow binding of divalent c ations. The molecular mechanism
of calcium binding of plant annexins requires further ... fold even among
the members of the plant subfamily of annexin proteins. The
fold is comprised of the arrangement o f four a-helical
domains into two modules, which are held together by polar
interactions....
- 8
- 475
- 0
Báo cáo khoa học: Revisiting the 13C-label distribution of the non-oxidative branch of the pentose phosphate pathway based upon kinetic and genetic evidence doc
Ngày tải lên :
23/03/2014, 15:21
... formed
between the carbonyl group of the ketose substrate
(f6p, s7p) and the e-amino group of a lysine residue of
the active site of the enzyme, leading to the formation
of either g3p or e4p ... rerouting of metabolic
fluxes was observed. The incorporation of genetic
knowledge into the metabolic network model for the
nonoxidative branch of the PPP introduced the possi-
bility of modeling the ... expected, the
largest differences are found for the PPP split-ratio and
the fluxes of the nonoxidative branch of the PPP.
The minimized covariance-weighted sum of
squared residuals (SS
res
) in these...
- 13
- 443
- 0
Extracted from the 17th edition of Which MBA? docx
Ngày tải lên :
23/03/2014, 18:20
... published as part of the school’s profile
in the directory section of this book.
Other rankings have some, but not all, of the above features.
How did we choose which schools to rank?
The Economist ... services; the range and suitability of teaching methods; the attitude and receptiveness
of faculty; the attitude of programme and school administrators; and the extent and useful-
ness of the alumni ... network of alumni.
13
Which MBA? © The Economist Intelligence Unit Limited 2005
Which skills will tomorrow’s leader need?
Extracted from the 17th edition of Which MBA?
Table 1.7
Which type of provider...
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- 0
The History of Banks: To Which Is Added, a Demonstration of the Advantages and Necessity of Free Competi- tion In the Business of Banking. Richard Hildreth doc
Ngày tải lên :
29/03/2014, 07:20
... consist in this. When they
need, in the course of their business, the use of the floating capital which
they have invested in the bank, they can borrow of the bank to the amount
of their stock, and ... specie as they
had, or sent it out of the kingdom.
The Royal Bank and the Company of the Indias were now incorpo-
The History of Banks/9
The conveniency of these notes soon spread them over the kingdom;
and ... gap in the circulation, the banks,
having constantly the terror of a run before their eyes, are obliged to
enlarge it. By the diminution of its total amount, the value of the parts of
which the...
- 78
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- 0
Báo cáo khoa học: Oxidative neuronal injury The dark side of ERK1/2 potx
Ngày tải lên :
30/03/2014, 13:20
... functions of
b-arrestins, or by modulating the activity of protein
kinase C, which can activate Raf isoforms at the apex of
the ERK1/2 module (reviewed in [42]).
Redox regulation at each of these ... especially those in the MKP family,
share a docking domain with high affinity for binding
ERK1/2 [58]. Several of these phosphatases are restricted
either to the cytoplasm (e.g. MKP3) or to the nucleus ... indicate
the presence of phosphorylated ERK1/2 in association with
fibrillar bundles, distended mitochondria and autophago-
somes [52]. These discrete accumulations of ERK1/2 in the
cytoplasm raise the...
- 7
- 359
- 0
A STUDY ON THE STRUCTURAL FEATUES OF ENGLISH NEWS STORY.DOC
Ngày tải lên :
02/09/2012, 11:12
... parts: the topic and the
controlling idea.
- The topic sentence is the subject of the paragraph.
Eg:
The color yellow is the color of mental activity.
The topic: the color yellow
- The controlling ... structure, the sub-title, and the discourse of the news
story.
From which, I would like to draw some difficulties of Vietnamese
readers when they translate the news story.
To sum up, the scope of the ... study which introduces my reasons and
aims to write the thesis. This part includes the aims, scopes, methods and
design of the study.
Part B is the main part of the study that consists of three...
- 62
- 1.1K
- 5
The chart below shows the sleep patterns of people in five different occupations according to a Canadian study
Ngày tải lên :
04/10/2012, 10:02
... wake at 6 a.m., but nap for two hours or so in the early afternoon. Thus the influence on one's
sleep pattern is worthy of consideration when choosing an occupation.
...
- 2
- 1.4K
- 3
- the four modules of the ielts
- oxidative functions of polymorphonuclear neutrophils pmns
- which completes the modification of eif5a through hydroxylation of deoxyhypusine
- the first law of thermodynamics is related to the conservation of which quantity
- which are true about the flotation cost of raising capital
- which of the following is not a correct statement about the second law of thermodynamics and entropy
- which of the following is a correct statement of the second law of thermodynamics
- the first law of thermodynamics is a restatement of which of these laws
- the basic structure of a sentence in spanish would be which one of the following
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