what hormone is responsible for increasing blood calcium levels and decreasing blood phosphate ion levels
Báo cáo khoa học: A characteristic Glu17 residue of pig carnitine palmitoyltransferase 1 is responsible for the low Km for carnitine and the low sensitivity to malonyl-CoA inhibition of the enzyme docx
... referredto as CPT1A, CPT1B, and CPT1C. Whereas CPT1A is widely expressed in most tissues, CPT1B is onlyexpressed in muscle, adipose tissue, heart, and testis[1], and CPT1C expression seems to be restricted ... occurring variation, Glu17, is responsible for both the low malonyl-CoA sensitivity and high carnitine affinity characteristics of the pig enzyme.This is the first demonstration that a single ... part, for the highdegree of inhibition of the human enzyme.Experimental proceduresConstruction of deletions D18PigCPT1B and D28PigCPT1B for CPT1B expression in P. pastorisThe deletions D18PigCPT1B...
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Báo cáo khoa học: A novel factor XI missense mutation (Val371Ile) in the activation loop is responsible for a case of mild type II factor XI deficiency doc
... site and a sub-strate-binding site for factor IX. Blood 74, 244–251.10 Bouma BN & Griffin JH (1977) Human blood coagula-tion factor XI. Purification, properties, and mechanismof activation ... AA, Gilchrist GS & Owen WG (1996)Genetic analysis and functional characterization of pro-thrombins Corpus Christi (Arg382–Cys), Dhahran(Arg271–His), and hypoprothrombinemia. Blood 88,2611–2618.30 ... FXI levels and hemorrhagic episodes are usu-ally associated with injury or surgery, but may be sosevere as to demand replacement therapy [16].The genetic basis of this rare coagulation disorder...
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Báo cáo khoa học: Direct CIII–HflB interaction is responsible for the inhibition of the HflB (FtsH)-mediated proteolysis of Escherichia coli r32 by kCIII docx
... thetranscriptional factor that favors lysogeny and is responsible for primary control of the lambda develop-mental decision for lysis or lysogeny [4,7–9]. In theabsence of CIII, CII is rapidly ... a lack of interaction between r32 and CIII (Fig. 4). As for CII, competition between r32 and CIII for binding to HflB would also decide the extent and efficiency of protection of r32by CIII, ... affinity for r32–HflB interaction and CIII–HflB interactionwould play an important role in the inhibition ofproteolysis of r32by HflB.Interestingly, both CII and r32are cytosolic sub-strates for...
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Báo cáo khoa học: PSI1 is responsible for the stearic acid enrichment that is characteristic of phosphatidylinositol in yeast pdf
... synthesis, it might be involved in the stearicacid incorporation after the de novo synthesis of thislipid (i.e. the second hypothesis). According to thishypothesis, previously raised for mammals ... t-test.AcknowledgementsWe thank Stephen Manon and Nadine Camougrand(IBGC, Universite´de Bordeaux ⁄ CNRS) for helpfuldiscussions. This work was supported by the CNRS and the Conseil Re´gional Aquitaine. Work at ... ofsn-2-acyl-1-lysoPI and 1 nmol of [14C]stearoyl-CoA. Incu-bations were performed at 30 °C for 10 min. Reactionswere stopped by the addition of 2 mL of chloroform ⁄ meth-anol (2 : 1, v ⁄ v) and 500 lL...
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Báo cáo khoa học: Redox reaction between amino-(3,4-dihydroxyphenyl)methyl phosphonic acid and dopaquinone is responsible for the apparent inhibitory effect on tyrosinase doc
... site for the hydroxylation reaction to occur. The same seems to hold for the derivatives of mandelic acid: 3,4-dihydroxymandelicacid is oxidized by tyrosinase, whereas 4-hydroxymandelicacid is ... should bepoor substrates for tyrosinase. On the other hand, 3,4-dihydroxybenzoic acid inhibited the dopachrome forma-tion, although the exact mechanism of this reaction has notbeen investigated ... reaction was assayed spectrophotometrically [13].However, we have now shown that it does not result fromits interaction with the enzyme but from chemical reactionsin solution. What distinguishes...
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Báo cáo khoa học: Knock-out of the chloroplast-encoded PSI-J subunit of photosystem I in Nicotiana tabacum PSI-J is required for efficient electron transfer and stable accumulation of photosystem I pot
... procedure.AcknowledgementsWe wish to thank Ingrid Duschanek and Elli Gerick for excellent technical assistance, and Steen Malmmose for assistance with growing plants. The DanishNational Research Foundation, the Danish ... containing2% sucrose, and grown in 12 h dark ⁄ light cycles at 25 °C and 20 l mol photonsÆm)2Æs)1 and, under selective condi-tions, 500 lgÆmL)1spectinomycin. For thylakoid isolation and physiological ... nmcaused by photo-oxidation of P700 to P700+, followedby a slower absorption decrease due to reduction ofP700+by Pc. The reaction between Pc and P700 is amultistep reaction, which can be divided...
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Báo cáo khoa học: TioS T-TE – a prototypical thioesterase responsible for cyclodimerization of the quinoline- and quinoxaline-type class of chromodepsipeptides potx
... side-chain mediating cyclization [18].Substitution of this position with l-Cys1 (TL6) abol-ished ligation and subsequent cyclization resulting incomplete hydrolysis. This observation indicates thatonly ... the C-terminal amino acid is essential for recogni-tion of the substrate and subsequent ligation and macrocyclization. In addition, we speculated thatS-methyl-l-Cys4 is incorporated into the ... activity.N-methylation induces conformational changes and elevates rotational barriers [41]. This rigidification ofmolecular dynamics gives rise to a preferential prefoldof the oligopeptide. The substitution...
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Selling Financial Products - A proven methodology for increasing sales of banking and financial services doc
... positioning of our client vis-à-vis competitorsPreparation of course materials: Submission of course materials to client for approvalPsychometric Questionnaire: Using Thomas International ... Capital Markets and Risk■ Risks in derivatives■ Fixed income and swaps■ Treasury risk management■ Asset and liabilitymanagement■ Credit derivatives■ Asset securitisation and CDOs■ Commodity ... TrainingCredit Analysis■ Accounting concepts and developments■ Corporate credit analysis■ Credit portfolio riskmanagement■ Bank and country risk analysis■ Analysis of non-bankfinancials■...
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Tài liệu Báo cáo khoa học: Is ATP binding responsible for initiating drug translocation by the multidrug transporter ABCG2? docx
... post-hydrolysis. Therefore, the dissoci-ation of phosphate and ⁄ or ADP is likely to be responsible for resettingof the transporter. The data indicate that, like ABCB1 and ABCC1,the ‘power stroke’ for ... a conformation that containsa low-affinity binding site for [3H]daunomycin imme-diately post-nucleotide hydrolysis.DiscussionA precise molecular mechanism for substrate translo-cation by ... high-affinityconformation for the transporter, which is supportedby the restoration of high-affinity binding in the ADP-bound conformation. That this step of the catalyticcycle is associated...
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Tài liệu Báo cáo Y học: Interallelic recombination is probably responsible for the occurrence of a new as1-casein variant found in the goat species potx
... mentioned b eforeexcept for the primer c oncentration (50 pmolÆ50 lL)1reac-tion mix) and the concentration of the agarose slab gel usedto visualize the PCR products was 4% (2% Gibco-BRL and 2% ... 5¢ and 3¢ flankingregions of each exon allowed us to identify 23 single nuc-leotide polymorphisms and two i nsertion/deletion events inthe coding as well as the noncoding regions. A comparison ... 265/266-bpfragment is split into two fragments (240 and 26 bp) for each allele e xcept the M and F alleles, for wh ich no TaqIsitehas been created (Fig. 8, Step IB), because of mutations(deletion o r...
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Báo cáo khoa học: The calcium-binding domain of the stress protein SEP53 is required for survival in response to deoxycholic acid-mediated injury pdf
... wavelengths. (A, excitation and emission at 340 nmwhen Fura-2 is bound to calcium; B, excitation and emis-sion at 380 nm when Fura-2 is free). Intracellular calcium levels can then be calculated ... antibodies to SEP53 and the human SEP53gene was cloned into a bacterial and insect cell-expres-sion system for the purification and acquisition offull-length protein for immunization, and to develop ... is that there is a relatively high degree ofcell and tissue specificity in HSP and related stress-acti-vated transcription factor induction [39–44]. Consistentwith this, our initial analysis...
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- responsible for increasing
- hormone responsible for increasing blood calcium levels
- hormone responsible for increasing blood sugar
- hormone responsible for increasing glucose uptake by cells
- responsible for increasing calcium levels in the blood
- which hormone is responsible for lowering blood calcium levels and decreased bone resorption
- what hormone is responsible for raising calcium blood levels
- which branch of the autonomic nervous system is responsible for increasing heart rate
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