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Tài liệu Báo cáo Y học: Proteolysis of bovine b-lactoglobulin during thermal treatment in subdenaturing conditions highlights some structural features of the temperature-modified protein and yields fragments with low immunoreactivity pptx
... pressure [10].Arg148 is not the only buried arginine in the structure of BLG. The whole side chain of Arg40 (the other main point of trypsin action) in the native structure of the protein isdeeply ... ratioenzyme/BLG of 1 : 20 or of 1 : 10. The protein/proteasemixture was then placed in a thermostatted water b ath for the required amount of time. At the end of the heattreatment the mixtures were placed ... thermal inactivation of both enzymes at this temperatureprevented further degradation of some hydrolysis interme-diates formed in the e arliest steps of proteolysis. The peculiar nature of...
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Báo cáo khoa học: Variants of b2-microglobulin cleaved at lysine-58 retain the main conformational features of the native protein but are more conformationally heterogeneous and unstable at physiological temperature potx
... peptide. Shown are the summed peakareas P (total area of f + s peaks) divided by the marker peakarea M at different time points as a percentage of the initialvalue of P ⁄ M at the onset of the experiments ... heterogeneity. The proton chemical shifts of the alternativeconformer (I2) of cK58-b2m are comparedwith the corresponding values of the nat-ively folded form of cK58-b2m in the graph. The two conformers ... doubling at the loca-tions and to the extent reported in Fig. 9. The features of the pattern of the second conformer resemble the features of a minor monomeric intermediate occurringalong the b2m-refolding...
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Testing Some Suprasegmental Features of English Speech
... StressWhether the testees have the ability to identify word stress can be tested by having them listen to tape-recorded list of words. The teacher can have the option of supplying testees with the ... video-recorder. (In the absence of these facilities, teacher can act it out.) In this listening activity, the teacher has the option of letting the testees follow the written script they earlier read. ... drawn'. First, the testees should be informed in advance of all the steps they are to follow in the test . The testees can first be given a dialogue, text, etc. to read. Second, they can be instructed...
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Báo cáo khoa học: Saccharomyces cerevisiae Ybr004c and its human homologue are required for addition of the second mannose during glycosylphosphatidylinositol precursor assembly ppt
... beenimplicated in all but one of the predicted reactions in the GPI pathway. The exception is the addition of the second mannose to the GPI core. We show here thatdepletion of the essential, multispanning ... Ybr004cp func-tions upstream of Smp3p. Together, these data furthersupport the conclusion that Ybr004cp functions in the yeast GPI assembly pathway.Sequence analysis of the Ybr004cp protein familyDatabase ... cells leads to the bio-chemical defects expected if addition of the second,a-1,6-linked mannose to GPI precursors is prevented.These defects are a block in the incorporation of [3H]inositol...
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Báo cáo khoa học: Unique features of the hemoglobin system of the Antarctic notothenioid fish Gobionotothen gibberifrons ppt
... 4,14]. The two Hbs have the b-chain in common, with the exception of those of Cygnodraco mawsoni [15] which share the a-chain. Therefore, Nototheniidae (and all Notothe-nioidei) are generally characterized ... acuticeps and C. mawsoni).However, the lack of a clear relationship with the Hbsequences of other nototheniid species suggests that in thiscase the evolution of the oxygen-transport system hasoccurred ... Fishes of the SouthernOcean. Smith Institute of Ichthyology, South Africa.21. Balushkin, A.V. (1992) Classification, phylogenetic relationships,and origins of the families of the suborder Notothenioidei(Perciformes)....
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Báo cáo khoa học: Enzymatic features of the glucose metabolism in tumor cells ppt
... iscapable of reducing the level of fructose 2,6-P2inde-pendent of the phosphorylation state of iPFK-2.Reducing the level of fructose 2,6-P2and thus the activity of PFK-1 improves the supply of ... changing the activity of the enzyme by x%results in a significant change of the pathway flux byat least 0.5x% (whether 0.5x% or higher is a matter of convention). The way that the change of enzyme ... regard to the explanation of the regulatory basis and physiological significance of the Warburg effect. We conclude that, besides the expression level of the meta-bolic enzymes involved in the glucose...
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Báo cáo khoa học: Mercury(II) binding to metallothioneins Variables governing the formation and structural features of the mammalian Hg-MT species pptx
... that the stoichiometries of the Hg-bMT species becomedependent on t and X after t he forma tion of Hg7-bMT.Comparison of the three sets of CD data indicates that the degree of chirality of the ... andreforming of the metal-sulfur bonds are well documentedfor t he group 12 metal thiolates in solution [26]. On the other hand, the mechanism involved in the binding of Table 1. Influence of the reaction ... stereo-chemistry and degree of folding of the species formed. Thus,to understand the reaction pathways followed by Zn-MTand apo-MT species in the presence of Hg(II), the e ffect of each of the previous variables...
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Báo cáo hóa học: " Some psychometric properties of the Chinese version of the Modified Dental Anxiety Scale with cross validation" pptx
... shown by the substantialreduction in chi-square value with a single degree of free-dom (the chi-square difference).On the strength of the positive evidence of overlap in itemcontent of the first ... test-ing of the factorial structure (Objective 1) and assist withproviding further evidence for the construct validity of the scale (Objective 2) by testing the strength of the hypothe-sised ... questions of the scale (namely 'mdas1' and 'mdas2'). The questioncontent of these 2 items focused on the anticipation of anxiety before entering the dental surgery, hence theseitems...
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Báo cáo toán học: " Some certain properties of the generalized hypercubical functions" ppt
... −232π2−463. The fourth derivative of the HC on the argument n, and the common radius is of the formFigure 8 The HC and its derivative with the HC maximum location and optimum for the value of the degree ... 2).In general, the HC of the mth derivative of n can be defined on the basis of the pro-duct of polygamma (psi) polynomial of the mth degree and HC. Its general form is the followingchm(k, ... 2011:60http://www.advancesindifferenceequations.com/content/2011/1/60Page 8 of 14comes down to zero. The greatest values of the considered functions are infinite, whenk0= ∞.2.7. The first derivatives of the ch1 function of HC in relation to the degree of freedom...
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Báo cáo hóa học: " Research Article Some Equivalent Forms of the Arithematic-Geometric Mean Inequality in Probability: A Survey" pptx
... with Y and 0, respectively.4 Journal of Inequalities and ApplicationsProof. The sketch of the proof of this theorem is illustrated by the following maps of equivalent circles:1E3 ⇒ H0 ... found in 1, 2,4, 5. The proof of the equivalent relations of E1, E2, E8, E9, E10,andE11 can befound in 3.Theorem 2.2. The following inequalities are equivalent.H0 ... expectation of the reciprocal of apositive random variable,” The Americam Statistician, vol. 21, no. 4, pp. 33–34, 1967.19 X. F. Zong, “A further generalization of the Cauchy inequality,” Journal of...
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Some Famous Problems of the Theory of Numbers and in particular pdf
... thatrepetitions of the same α are permissible; that the order of the α’s isirrelevant; and that s, the number of the α’s, is unrestricted. Then itis easy to see that r(n), the number of representations, ... Lagrange’s theorem, any number X is the sum of 4 squares, it follows that any number of the form 6X2is the sum of 12 biquadrates. Hence any number of the form 6(X2+Y2+Z2+T2)or, what is the ... encoding: ISO-8859-1*** START OF THIS PROJECT GUTENBERG EBOOK FAMOUS PROBLEMS OF THEORY OF NUMBERS ***End of the Project Gutenberg EBook of Some Famous Problems of the Theory of Numbers and in particular...
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