west nile virus basic principles replication mechanism immune response and important genetic
Báo cáo hóa học: " In vitro effects of selenium deficiency on West Nile virus replication and cytopathogenicity" ppt
... flaviviruses: the spread and resurgence of Japanese encephalitis, West Nile and dengue viruses Nat Med 2004, 10(12 Suppl):S98-109 Samuel MA, Diamond MS: Pathogenesis of West Nile Virus infection: a ... hepatitis B and C viruses [6] Moreover, point mutations in Coxsackie virus B3 (CVB3/0) and influenza A virus (H3N2) have been associated with increased disease severity in Se-deficient mice [7-9], and ... demonstrated to enhance HIV replication in Tlymphocytic and monocytic cells [10-12] Thus, Se deficiency leads to increased virulence and evolution of viral quasispecies [13,14] West Nile virus (WNV), a mosquito-borne...
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The involvement of cellular components in west nile virus replication cycle
... RECOMBINANT WEST NILE VIRUS E DIII BINDS TO αVβ3 INTEGRIN AND PREVENTS WEST NILE VIRUS ENTRY 156 CHAPTER 160 5.0 THE GRAND ENTRANCE OF WEST NILE VIRUS 160 5.1 INTRODUCTION 160 5.2 ENTRY ROUTE OF WEST NILE ... INHIBITION OF WEST NILE VIRUS ENTRY WITH SOLUBLE RECOMBINANT WEST NILE VIRUS- DIII PROTEIN 4.12 151 MURINE POLYCLONAL ANTIBODY TO RECOMBINANT WEST NILE VIRUS- DIII NEUTRALIZED WEST NILE VIRUS 4.13 ... WEST NILE VIRUS BINDING AND PENETRATION INTO CELLS 4.4 EFFECTS OF INTEGRIN LIGANDS ON WEST NILE VIRUS ENTRY INTO CELLS 4.5 130 136 GENE SILENCING OF HUMAN β3 INTEGRIN SUBUNITS INHIBITS WEST NILE...
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Báo cáo khoa học: NMR study of complexes between low molecular mass inhibitors and the West Nile virus NS2B–NS3 protease ppt
... dengue and West Nile virus Nat Struct Mol Biol 13, 372–373 Robin G, Chappell K, Stoermer MJ, Hu S, Young PR, Fairlie DP & Martin JL (2009) Structure of West Nile virus NS3 protease: ligand stabilization ... cross-peak between H3 and H6 or H6¢ is assigned as well as the intramolecular NOE between H3 and H1 Table Intermolecular NOEs between West Nile virus (WNV) NS2B–NS3pro(K96A) and inhibitors and Protons ... Cd1H3 Tyr161 Hd a Compound H1 and CH3 H6 ⁄ H6¢ H6 ⁄ H6¢ H6 ⁄ H6¢ H6 ⁄ H6¢ H6 ⁄ H6¢ H1 H1, H2, H5 ⁄ H5¢ H1, H2, H3, H4 H1 and CH3 H1 and CH3 H1 and CH3 H1 and CH3 H1 and CH3 NOEs identified in Fig...
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Norwalk virus, west nile virus, hanta virus
... for vaccine development The case of the flu Influenza virus A (B, C) Infects respiratory tract -Cells killed by virus or immune response Immune mediators: Interferon -fever -muscle aches -headaches ... Antigenic shift and flu pandemics Shift (Reassortment): viral gene segments randomly reassociate -Achieved by co-infection of a single cell with these viruses How does this happen? Virus shed in ... Antigenic shift and flu pandemics Shift - Reassortment: viral gene segments randomly reassociate -Achieved by co-infection of a single cell with these viruses How does this happen? Virus shed in...
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Báo cáo sinh học: " The Israeli strain IS-98-ST1 of West Nile virus as viral model for West Nile encephalitis in the Old World" pdf
... neuropathology of West Nile virus FEMS Microbiol Lett 2004, 233:1-6 Beasley DW, Li L, Suderman MT, Barrett AD: Mouse neuroinvasive phenotype of West Nile virus strains varies depending upon virus genotype ... defense of disseminated infection by West Nile encephalitis virus J Virol 2003, 77:2578-2586 Xiao SY, Guzman H, Zhang H, Travassos da Rosa AP, Tesh RB: West Nile virus infection in the golden hamster ... studies, M-PF and TM participated in in vivo experiments, VD and J-LG revised critically the article, PD and P-EC have written, drafted the article, and participated to in vivo and ex-vivo experiments...
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Báo cáo sinh học: " Peptide inhibitors of dengue virus and West Nile virus infectivity" pot
... the fusion proteins of other retroviruses, and of orthomyxoviruses, paramyxoviruses, filoviruses, coronaviruses, and herpesviruses have also been identified and shown to inhibit viral entry [10-18] ... dengue virus; WNV: West Nile virus; YFV: yellow fever virus; SLEV: St Louis encephalitis virus; JEV: Japanese encephalitis virus; TBEV: Tickborne encephalitis virus; OHFV: Omsk hemorrhagic fever virus; ... triggering and fusion [21-28] http://www.virologyj.com/content/2/1/49 The flaviviruses, which include DENV, West Nile virus (WNV), yellow fever virus, Japanese encephalitis virus (JEV), and TBEV,...
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Báo cáo sinh học: " Actively replicating West Nile virus is resistant to cytoplasmic delivery of siRNA" ppt
... observed in plant viruses, and has been recently reported with several mammalian viruses including LaCrosse virus, adenovirus, and influenza A virus [3234,40-43] To determine if WNV replication directly ... translation and RNA replication occur [4] The positive strand genomic WNV RNA that associates with the ER is competent for translation and transcription of negative strand RNA WNV and related flaviviruses ... and proliferation of endoplasmic reticulum membranes induced by flaviviruses is essential for efficient replication [6,7,38] Uchil and Satchidanandam [46] proposed a model of flavivirus RNA replication...
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Báo cáo hóa học: " Detection of seroconversion to West Nile virus, Usutu virus and Sindbis virus in UK sentinel chickens" doc
... blot using gradient-purified West Nile virus antigen and sera (diluted 1/100) from sentinel chickens Figure Western blot using gradient-purified West Nile virus antigen and sera (diluted 1/100) from ... New York strain of West Nile virus Emerging Infectious Diseases 2003, 9:311-327 Murgue B, Zeller H, Deubel V: The Ecology and Epidemiology of West Nile Virus in Africa, Europe and Asia In Current ... Chamberland ME, Petersen LR: Transmission of West Nile virus from an organ donor to four transplant recipients New England Journal of Medicine 2003, 348:2196-2203 CDC: Possible West Nile virus...
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báo cáo hóa học:" Peptide inhibitors of dengue virus and West Nile virus infectivity" doc
... the fusion proteins of other retroviruses, and of orthomyxoviruses, paramyxoviruses, filoviruses, coronaviruses, and herpesviruses have also been identified and shown to inhibit viral entry [10-18] ... dengue virus; WNV: West Nile virus; YFV: yellow fever virus; SLEV: St Louis encephalitis virus; JEV: Japanese encephalitis virus; TBEV: Tickborne encephalitis virus; OHFV: Omsk hemorrhagic fever virus; ... triggering and fusion [21-28] http://www.virologyj.com/content/2/1/49 The flaviviruses, which include DENV, West Nile virus (WNV), yellow fever virus, Japanese encephalitis virus (JEV), and TBEV,...
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báo cáo hóa học:" Actively replicating West Nile virus is resistant to cytoplasmic delivery of siRNA" pptx
... observed in plant viruses, and has been recently reported with several mammalian viruses including LaCrosse virus, adenovirus, and influenza A virus [3234,40-43] To determine if WNV replication directly ... translation and RNA replication occur [4] The positive strand genomic WNV RNA that associates with the ER is competent for translation and transcription of negative strand RNA WNV and related flaviviruses ... and proliferation of endoplasmic reticulum membranes induced by flaviviruses is essential for efficient replication [6,7,38] Uchil and Satchidanandam [46] proposed a model of flavivirus RNA replication...
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Báo cáo y học: "Ocular Manifestations of West Nile Virus Infection" doc
... Chorioretinal involvement in patients with West Nile virus infection Ophthalmology 2004;111:2065-70 Garg S, Jampol LM Systemic and intraocular manifestations of West Nile virus infection Surv Ophthalmol ... ophthalmoscopy and FA in selected cases, should be part of the routine evaluation of patients with clinically suspected WNV infection References Hayes EB, Gubler DJ West Nile virus: epidemiology and clinical ... Int J Med Sci 2009, 115 vicides…) and personal protection against mosquito bites (repellants, window screens, protective clothing,…)...
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báo cáo khoa học: "Prognosis of West Nile virus associated acute flaccid paralysis: a case series" pdf
... for observation and further examination Serum IgM was positive for West Nile virus and a diagnosis of West Nile virus acute flaccid paralysis was made The delirium quickly cleared and after one ... admitted to the hospital for observation and further examination Serum IgM was positive for West Nile virus and an EMG was consistent with West Nile virus acute flaccid paralysis He was discharged ... puncture revealed 123 white blood cells/μL and protein of 1.27 g/ L in the CSF Serum IgM was positive for West Nile virus and a diagnosis of West Nile virus acute flaccid paralysis was made While...
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báo cáo khoa học: "A nano-view of West Nile virus-induced cellular changes during infection" pps
... ultra-structural studies Results and Discussion West Nile (Sarafend) virus- induced changes in infected cells at late stage infection At the late stages of West Nile (Sarafend) virus infection in Vero ... height scan of West Nile virus- infected Vero cells at 24 h p.i (a) AFM1 (a) AFM height scan of West Nile virus- infected Vero cells at 24 h p.i Scan size is 251 nm × 251 nm A progeny virus (arrow) ... height scan of West Nile virus- infected Vero cells at 24 h p.i Scan size is 98.4 nm × 98.4 nm Arrowhead shows the envelope surrounding the budding progeny virus (c) TEM image of West Nile virus- infected...
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Báo cáo y học: " The natural history of West Nile virus infection presenting with West Nile virus meningoencephalitis in a man with a prolonged illness: a case report" doc
... Control and Prevention, Division of Vector-Borne Infectious Diseases, West Nile virus: fight the bite! http://www.cdc.gov/ ncidod/dvbid/westnile/index.htm R Voelker, Effects of West Nile virus ... Disease Control and Prevention; CMV: cytomegalovirus; CSF: cerebrospinal fluid; HSV: herpes simplex virus; MRI: magnetic resonance imaging; TB: tuberculosis; WNND: West Nile virus neuroinvasive ... The outbreak of West Nile virus infection in the New York City area in 1999 N Engl J Med 344, 1807–1814 (2001) doi:10.1056/NEJM200106143442401 LR Petersen, EB Hayes, West Nile virus in the Americas...
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Báo cáo y học: " First serological evidence of West Nile virus in human rural populations of Gabon" pdf
... pathology, and clinical manifestations of West Nile virus disease Emerg Infect Dis 2005, 11:1174-1179 Murgue B, Zeller H, Deubel V: The ecology and epidemiology of West Nile virus in Africa, Europe and ... JH, Hubalek Z: Migratory birds and West Nile virus J Appl Microbiol 2003, 94(Suppl):47S-58S Blitvich BJ: Transmission dynamics and changing epidemiology of West Nile virus Anim Health Res Rev 2008, ... http://www.virologyj.com/content/7/1/132 Page of Table 1: West Nile fever virus- specific IgG prevalence according to villagers' sex and age and the ecosystem Characteristics Variable IgG + (%) 95%...
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Báo cáo y học: "A VLP-based vaccine targeting domain III of the West Nile virus E protein protects from lethal infection in mice" pptx
... of West Nile virus induces protective immune responses against influenza and West Nile virus PLOS One in press 35 Huang CY, Silengo SJ, Whiteman MC, Kinney RM: Chimeric dengue PDK-53 /West Nile ... Campbell GL: The epidemic of West Nile virus in the United States, 2002 Vector Borne Zoonotic Dis 2004, 4:61-70 Gubler DJ: The continuing spread of West Nile virus in the western hemisphere Clin Infect ... therapeutic potential against West Nile virus Nat Medicine 2005, 11:522-530 20 Wang T, Anderson JF, Magnarelli LA, Wong SJ, Koski RA, Fikrig E: Immunization of mice against West Nile virus with recombinant...
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Báo cáo khoa học: "Recombination in West Nile Virus: minimal contribution to genomic diversity" ppt
... Methods Multiple Sequence Alignments and Phylogenetic Trees To look for recombination in WNV isolates, we used 154 whole genome Kunjin virus and West Nile virus sequences (See additional file ... Old World West Nile virus strains Virology 2003, 315:381-388 Davis LE, DeBiasi R, Goade DE, Haaland KY, Harrington JA, Harnar JB, Pergam SA, King MK, DeMasters BK, Tyler KL: West Nile virus neuroinvasive ... Genome Phylogenetic Tree Whole Genome Phylogenetic Tree Bayesian phylogenetic tree reconstruction of 154 whole genomic WNV (and Kunjin virus) sequences The distinct lineages are maintained and are...
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Báo cáo khoa học: "Diversification of West Nile virus in a subtropical region" pptx
... of west nile virus Curr Mol Med 2005, 5:835-850 Meulen KM van der, Pensaert MB, Nauwynck HJ: West Nile virus in the vertebrate world Arch Virol 2005, 150:637-657 Kramer LD, Li J, Shi PY: West Nile ... 0.0009 * = NT, nucleotide; AA, amino acid Figure West Nile virus envelope protein model West Nile virus envelope protein model The histadines are noted and residues of interest boxed Page of (page ... LD: Genetic and phenotypic variation of West Nile virus in New York, 2000–2003 Am J Trop Med Hyg 2004, 71:493-500 Moudy RM, Meola MA, Morin LL, Ebel GD, Kramer LD: A newly emergent genotype of West...
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Báo cáo khoa học: "Diversification of West Nile virus in a subtropical region" potx
... of west nile virus Curr Mol Med 2005, 5:835-850 Meulen KM van der, Pensaert MB, Nauwynck HJ: West Nile virus in the vertebrate world Arch Virol 2005, 150:637-657 Kramer LD, Li J, Shi PY: West Nile ... 0.0009 * = NT, nucleotide; AA, amino acid Figure West Nile virus envelope protein model West Nile virus envelope protein model The histadines are noted and residues of interest boxed Page of (page ... LD: Genetic and phenotypic variation of West Nile virus in New York, 2000–2003 Am J Trop Med Hyg 2004, 71:493-500 Moudy RM, Meola MA, Morin LL, Ebel GD, Kramer LD: A newly emergent genotype of West...
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