... regarding brainstem control ofsleep and breathingThe third provides comprehensive reviews of experimental methods utilizing experimentally induced breathing disorders in sleeping animals These ... relevance, there is major interest in determining the role of stimuli involved with sleep- disordered breathing (e.g., intermittent hypoxia or arousals from sleep) and the mechanisms underlying the adverse ... Overview: Research on Sleep and Breathingin Rodents Sleep Recordings in Rats Sleep Recordings in Mice Application of Plethysmography to Research inSleep and Breathingin Rodents References...
... study the mechanism of antiHIV-1 integrase Evidence suggests that curcumin does not bind to HIV-1 integrase at either the DNA-binding domain [58] or the binding site of another HIV-1 integrase inhibitor, ... HIV-1 integrase is the enzyme that catalyzes the integration ofthe doublestrained DNA of HIV into the host chromosome [54] Curcumin inhibited this activity of HIV-1 integrase [54] Other classes of ... phytohematoglutinin, concanavalin A, and pokeweed mitogen were examined inthe presence of AZT, curcumin, and turmerin In infective assays, neither turmerin nor curcumin of a phenolic OH group for the anti-oxidant...
... analyses The feasibility of conducting quality of life interviews among TB patients using the MOS in urban Uganda setting was evaluated by examining the percent of missing item responses, interviewer-reported ... further evaluation in prospective studies and after teasing the effect of HIV disease severity Results ofthe psychometric testing ofthe MOS in a population of patients with pulmonary TB inthe ... evaluations of their own health states using the VAS and MOS The construct validityof HRQoL scores was evaluated in four ways: 1) the researchers hypothesized that there would be differences in the...
... to mainstream the regional dimension inthe overall work ofthe United Nations inthe economic and social sectors Inthe view ofthe executive secretaries, the Summit Outcome underlines the need ... engines of growth ofthe global economy and as the source of growing intraregional trade, investment and technology The dynamism inthe regions also has a significant bearing on strengthening ... ofthe varying infrastructural needs and financing gaps, the executive secretaries exchanged views on the multiple sources of financing available in their regions to meet those needs, including...
... any ofthe others Construct validity was tested with the following two analyses The ability ofthe MOS -Sleep scores to discriminate between groups of subjects according to the severity ofthe ... level of pain: the higher the mean pain score at baseline, the higher the mean scores ofthe dimensions "awaken short of breath or headache," "somnolence" and "sleep disturbance," and ofthesleep ... for the other MOS -Sleep dimensions Mean changes inthesleep problems index score differed according to the changes in health status over the 12-week study: change inthesleep problems index...
... located on the intact protein Therefore, determination ofthe kinetics of phosphorylation of these peptides allows the order of phosphorylation ofthe six TCRf ITAM tyrosines, by the PTK Lck, ... arising inthe order of phosphorylation ofthe subsequent tyrosines inthe whole cTCRf chain in vitro, relative to the single-tyrosine-containing peptides, may well be due to the presence of an ... Role of electrostatic interactions in SH2 domain recognition: salt dependence of tyrosyl-phosphorylated peptide binding to the tandem SH2 domain ofthe Syk kinase and the single SH2 domain of the...
... Master of A r t s T i t l e of Thesis r A Investigation i n t o Attitudes n Towards Water Pollution i n the Shuswap Lake Area of B r i t i s h Columbia Examining C omrnittee : Chairman: E J Hickin ... i t s of t h e 71 residents 29.0pinions concerning t h e s e r i o u s n e s s of water p o l l u ti0ninB.C 73 30.0pinion concerning Shuswap Lake water q u a l i t y 73 31.0pinion concerning f ... 45 Age of t h e sample 46 Location of t h o s e interviewed Occupation of t h e sample 46 Education of t h e sample 47 Income of t h e sample 48 Importance of water...
... history Inthe literature relating to thevalidityinthe diagnosis ofthe clinical features and history we did not find specific values More frequently observed findings are given The absence of ... typical of TB (the presence of nodular, alveolar, or interstitial infiltrates predominantly affecting the zones above the clavicles or upper zones; the presence of cavitation affecting the upper ... Conclusion In our study, thevalidityofthe diagnostic methods for the tuberculosis is compatible with the literature These methods inthe diagnosis of tuberculosis are still valid The minor diversity...
... only to the test context Before completing the questionnaire, the subjects were informed ofthe objectives of collecting the data, the detailed description ofthe questionnaire, plus instructions ... significance of listening and benefits of using the right strategies with the right tasks They can also serve as guidelines for teachers who would like to provide strategy training in English listening instruction, ... practicing listening to news, and reviewing in advance) strategy training should be underlined since they have great influence on listening comprehension Moreover, taking notes while listening and...
... interpreting data There should be an open-ended question inthe survey of TWU to investigate the perceptions/ expectations or thinking ofthe respondents Coding plan Coding plan is the collection of ... means there is insufficient evidence to suggest that a difference exists inthe amount of usage ofthe Safe Bus intern of gender 2.5.2 The amount of usage ofthe Safety bus differ by origin In this ... some limitations to the investigators in term ofthe results are not cover the aims ofthe business or too wide to conclude the status ofthe strategy Therefore, TWU targets the random sample size...
... widely applied inthe broader health -related quality of life literature [35-40] It is defined as the ratio ofthe square ofthe t-statistic ofthe comparator instrument (assumed to be the SF-6D utility ... indication ofthe subject's own assessment of their health status on the day ofthe survey [13,25] The women inthe present study were asked to complete the EQ-5D descriptive system and not the ... and the saved young life equivalent (SAVE) [6] The QALY synthesises information on the length of life and the healthrelated quality of life into a single measure of health outcome, and is the...
... assessment ofthe impact of FM on their sleep Nineteen ofthe participants said that the instrument captured all of their sleep- related symptoms, indicating likely concept saturation of these symptoms ... Therefore, the objectives ofthe current qualitative study were to further describe the impact of FM on participants' sleep and to evaluate the content validityof both of these measures inthe ... Quantity ofsleep Optimal sleepSleep adequacy Somnolence 1 1 Sleep Problem Index IId Trouble falling asleep (7); time to fall asleep (1); restless sleep (3); awaken during sleep (8) Snore during sleep...
... to use these mapping functions in future studies In these circumstances, the performance ofthe mapping function in estimating utility values needs to be assessed and the likely impact of decisions ... participated inthe design ofthe study and performed the statistical analysis and interpretation of data, and drafted the manuscript; ML participated inthe design ofthe study and the statistical ... was involved in revising the manuscript critically for important intellectual content; SV made substantial contributions to the acquisition ofthe data, was involved in drafting and revising the...
... sampling method [38] The sample size calculation was determined based upon the requirements ofthe broader study noted above The sampling frame was a list ofthe total population of IDPs living in ... sub-groups, determinants of health, and the impact of health -related interventions Health -Related Quality of Life (HRQOL) instruments provide a useful means of measuring health outcomes at the population ... [8] The correlations between the items and PCS and MCS components were then compared with the hypothesised correlations The variance explained (the percent ofthe total measured variance in the...
... the GSRS Reflux, Abdominal pain and Indigestion domains correlated with all QOLRAD domains inthe Spanish version ofthe questionnaires Correlation ofthe GSRS with the SF-36 Each domain ofthe ... low internal consistency inthe Abdominal pain domain probably reflects the difficulty of measuring this often fluctuating symptom, as well as the fact that the GSRS Abdominal pain domain contains ... functioning domains Inthe German versions, the GSRS Abdominal pain and Indigestion domains correlated with all QOLRAD domains, but the GSRS Reflux domain correlated only with the QOLRAD Food/drink...
... friends, swimming in chlorinated pools, riding horses, playing with pets, going to camp, eating certain foods, being indoor or outdoor, exercising, and sleeping [11-17] Without the use of effective ... Figure ofthe Participation in scores before summing the indicator Life Activities Scale is completed by computing the mean scores for each ofthe three indicators Scoring Scoring ofthe Participation ... collection Power analysis In determining sample size for psychometric testing, the number of items contained inthe target instrument, sensitivity of other instruments being used, and data analysis...
... p-value < 0.001) Discussion In this study we investigated the construct validityofthe Italian version ofthe EQ-5D administering the instrument to a sample of citizens living in Bologna (North Italy) ... affected by the clinical condition we obtained a 600% increased odds of reporting impairment inthe mobility domain (OR = 7.0, 95% C.I 4.7–10.4), a 690% increased odds of reporting impairment inthe ... affected by the clinical condition we obtained a 480% increased odds of reporting impairment inthe mobility domain (OR = 5.8, 95% C.I 4.0–8.3), a 430% increased odds inthe self-care domain, and...
... translation ofthe PedsQL™ 4.0 generic core scale in a healthy sample of young adolescents and their caregivers The results from the present study resemble the findings ofthe original PedsQL™ [9] and the ... provide further insight inthe degree of overlap between items hypothesized to measure different constructs, and also inthe equivalence of factor loadings on the items within a single factor The adolescent-parent ... emphasizing the clinically usefulness regarding child-parent discrepancies still when challenging thevalidityof measures 11 Competing interests The author(s) declare that they have no competing interests...
... 0.74) In all three cases the accuracy was considerably higher than the precision The CCQ scores ofthe patients were within the limits ofthe MCID ofthe scores ofthe treating clinician in 62% ... 62% and the mean score ofthe reviewing clinicians in 63% The proportion of cases within the MCID of 0.4 (CP 0.4 ) between treating clinician and reviewing clinicians was lower (0.50) There were ... an in- depth interview) is used as the gold standard, and the outcome ofthe in- depth interview is compared with the patient’s score on the questionnaire completed inthe clinic before the in- depth...
... However, the overwhelming majority (98%) of patients participating in our study were receiving antiretroviral therapy, which was rare during the time ofthe study At the time of this study, there ... as the interviewer) and the desire to minimize interpersonal conflict may influence patient response in intervieweradministration as interviewees will try to answer questions in a way they think ... approximately the same educational attainment with 60.0% of those completing each QOL battery having finished at least primary education The majority of individuals - 58.0% of those completing the MOS-HIV...