vaccine and cancer therapy for genitourinary tumors
Surface functionalization of superparamagnetic iron oxide nanoparticles for potential cell targeting, imaging, and cancer therapy applications
... than 41 oC Therefore, hyperthermia based on the generation of heat at the tumor site is a promising cancer therapy and is a supplementary treatment to chemotherapy, radiotherapy, and surgery (Lu ... tight junctions and cell membranes (Tyagi et al 2006) Therefore, drug-loaded magnetic particles are promising for overcoming the limitations of the traditional IDD for bladder cancer therapy They ... SPIONs and (b) PLMA2-SPIONs. Figure 3-6 Schematic representation of the synthesis of PLMA-1-PEGSPIONs Site and extent of amide band formation between H2NPEG and PLMA-1 are shown for illustration...
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Báo cáo y học: "Comparison between single antiplatelet therapy and combination of antiplatelet and anticoagulation therapy for secondary prevention in ischemic stroke patients with antiphospholipid syndrome"
... Int J Med Sci 2010, with APS We therefore compared single antiplatelet therapy and a combination of antiplatelet and anticoagulation therapy for secondary prevention in ischemic stroke ... miscarriages, and livedo reticularis Materials and Methods We focused on the secondary prevention of stroke with APS, and compared single antiplatelet therapy and a combination of antiplatelet and anticoagulation ... committee of Tokai University, and prior informed consent was obtained from all patients who were eligible to participate Randomization was performed using a randomly generated score Results...
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Addition of Clopidogrel to Aspirin and Fibrinolytic Therapy for Myocardial Infarction with ST-Segment Elevation pdf
... respectively; data on thrombus were available for 1622 and 1619 patients, respectively; and data on stenosis and the minimal luminal diameter were available for 1560 and 1559 patients, respectively CI denotes ... Reperfusion therapy for acute myocardial infarction with fibrinolytic therapy or combination reduced fibrinolytic therapy and platelet glycoprotein IIb/IIIa inhibition: the GUSTO V randomised trial ... unfractionated heparin as antithrombin therapy in patients receiving fibrinolysis for ST elevation MI: design and rationale for the Enoxaparin and Thrombolysis Reperfusion for Acute Myocardial Infarction...
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Báo cáo khoa học: "Improved survival following surgery and radiation therapy for olfactory neuroblastoma: analysis of the SEER database" pdf
... http://www.ro-journal.com/content/6/1/41 stratified by treatment was: 73% for surgery and radiotherapy, 68% for surgery only, 35% for radiotherapy only, and 26% for neither surgery nor radiotherapy There was a significant difference ... site and year of diagnosis The SEER historic staging variable provided information for the following categories: localized, regional, distant and unstaged Information for type, timing, and duration ... (surgery and radiotherapy, surgery only, radiotherapy only, and neither surgery nor radiotherapy) (p < 0.01) The percentage of cases surviving five years by treatment modality was: 73% for surgery and...
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báo cáo khoa học: "Evolution of T-cell clonality in a patient with Ph-negative acute lymphocytic leukemia occurring after interferon and imatinib therapy for Ph-positive chronic myeloid leukemia" pot
... Page of and post two courses of chemotherapy (CT) for Ph-negative ALL, respectively and 72°C for min, and a final elongation at 72° C Then, the products were stored at 4°C Cytogenetic, FISH and RT-PCR ... RT-PCR analysis for BCR/ABL detection Genescan analysis for TCR Va and TCR Vb subfamily clonality analysis Karyotype analyses were performed by R-banding technique FISH was performed using LSI·bcr/abl ... at 94°C for with 9.5 μl formamide (Hi-Di Formamide, ABI, USA) and 0.5 μl of Size Standards (GENESCAN™-500-LIZ™, Perkin Elmer, ABI), the samples were then loaded on 3100 POP-4™ gel (Performance...
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Báo cáo y học: " Overall asthma control achieved with budesonide/formoterol maintenance and reliever therapy for patients on different treatment steps" pps
... inhaler containing budesonide and formoterol for both maintenance therapy and relief of symptoms (option for Steps 3-5) This approach has been shown in several large-scale randomised controlled trials ... BUD/FORM maintenance and reliever therapy vs same maintenance dose ICS/ LABA + SABA, 247 patients (12.2%) vs 437 patients (21.4%), respectively [3,7]; and BUD/FORM maintenance and reliever therapy ... Budesonide/formoterol maintenance and reliever therapy vs same maintenance dose ICS/LABA + SABA Step Step Step Same maintenance ICS/ LABA + SABA (N = 375) BUD/FORM maintenance and reliever therapy...
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Improvement of different vaccine delivery systems for cancer therapy pptx
... suitable for when high doses and robust immune responses are desired such as cancer vaccines and gene therapy Clinical trials in progress and planned using Derma Vax include 1) Prostate cancer ... These polymers have been designated as feasible candidates for drug delivery systems, anti -cancer agents and vaccine immunotherapy For example, DNA vaccine delivery to APCs has been facilitated ... vaccination and gene therapy: optimization and delivery for cancer therapy Expert Rev Vaccines 2008, 7:1085-1101 25 Bolhassani A, Mohit E, Rafati S: Different spectra of therapeutic vaccine development...
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recombinant antibodies for cancer therapy, methods and protocols
... for Cancer Therapy: Methods and Protocols Edited by: M Welschof and J Krauss © Humana Press Inc., Totowa, NJ Kipriyanov Fig Domain organization of an IgG molecule Antigen-binding surface is formed ... for each reshaped antibody and can therefore be difficult to foresee Such approach was successfully used for humanizing a MAb 4D5 against the product of protooncogene HER2 (27) HER2 is a ligand-less ... with Fc receptors and complement and thus to trigger cytolysis and other immune reactions Human IgG1, for example, would be the constant region of choice for mediating ADCC and probably also...
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Báo cáo hóa học: " Development of targeted therapy for bladder cancer mediated by a double promoter plasmid expressing diphtheria toxin under the control of H19 and IGF2-P4 regulatory sequences" potx
... studies of our group and others, the transcriptional regulatory sequences of the H19 and IGF2 genes emerged as candidates for cancer targeted therapy H19 and IGF2 (the human P3 and P4 promoters) ... removed and the serosal surface and the adjacent sex glands were dissected carefully Samples of the tumors were fixed in 4% buffered formaldehyde and processed for histological examination for evidence ... patient Cancer Therapy 2005, 3:249-266 Cooper MJ: Noninfectious gene transfer and expression systems for cancer gene therapy Semin Oncol 1996, 23:172-187 Kouraklis G: Gene therapy for cancer: from...
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Báo cáo khoa học: "An investigation of intensity-modulated radiation therapy versus conventional two-dimensional and 3D-conformal radiation therapy for early stage larynx cancer" ppt
... prostate and head and neck tumors by allowing for dose escalation and better target coverage A number of papers in the past have shown that there is a dose response relationship for larynx cancer, ... of head -and- neck cancer Int J Radiat Oncol Biol Phys 2006, 66:469-476 Chen AM, Farwell DG, Luu Q, et al: Misses and near-misses after postoperative radiation therapy for head and neck cancer: ... radiation therapy versus conventional two-dimensional and 3D-conformal radiation therapy for early stage larynx cancer Radiation Oncology 2010 5:74 Submit your next manuscript to BioMed Central and...
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Báo cáo khoa học: "Target splitting in radiation therapy for lung cancer: further developments and exemplary treatment plans" pps
... withdrawn and the primary tumor alone is treated to 79,2 Gy V20 right and left lung and V25 both lungs is 49%, 22% and 26%, respectively V50 for the heart is 2% Peripheral tumor located lateral and ... innovations and implications for workflow and demonstrates exemplary treatment solutions in lung cancer patients with different tumor topographies (Figure 1, Figure 2, Figure 3, Figure 4, Figure and ... tinely for lung cancer patients in all stages During the past years, this technique has continuously been evolved with regard to optimizing the procedures for quality assurance and raising conformity...
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báo cáo khoa học: "Inflammatory myopathy and severe rhabdomyolysis induced by leuprolide acetate therapy for prostate cancer: a case report" pot
... strength in both his hands and his feet, but active lifting of his head, legs, and arms was barely possible while he was supine, and his speech was slurred His reflexes, eye movements, and cranial nerve ... creatinine 51 μmol/L, BUN 6.4 mmol/L, sodium 122 mmol/L, and potassium 4.3 mmol/L His serum 25OH vitamin D level and thyroid gland function were normal, and his human immunodeficiency virus test was negative ... the basis of his serum PSA and the fact that the size of the solitary node in his lung decreased during leuprolide acetate therapy, we assume that prostate cancer therapy was successful in our...
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báo cáo khoa học: "Free Rhodium (II) citrate and rhodium (II) citrate magnetic carriers as potential strategies for breast cancer therapy" docx
... investigator and takes primary responsibility for the paper MLBC, ZGML, ARS* and SNB participated in the design of the study and SNB co-ordinated the research; MLBC, ESN, RCAP, RGSO and LHML performed ... of a- and b-carboxyl carbon atoms in the complex (195.3 and 192.8 ppm, respectively) appear shifted in comparison with those with free ligands (179 and 176.5 ppm, respectively) The shift and split ... Diffraction pattern for sample Magh B) Magnetization curves at 300 K for bare: ○ maghemite (Magh), and ● modified maghemite (Magh-Rh2(H2cit)4) C) Infrared Spectra for _ Magh and - - - Magh-Rh2(H2cit)4;...
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IDENTIFICATION, KINETIC AND STRUCTURAL CHARACTERIZATION OF SMALL MOLECULE INHIBITORS OF ALDEHYDE DEHYDROGENASE 3A1 (ALDH3A1) AS AN ADJUVANT THERAPY FOR REVERSING CANCER CHEMO-RESISTANCE
... grateful to you for believing in me and letting me pursue my dreams The person I am today is because of you To my dear uncle and my aunt Khem Kandel and Laxmi Kandel: your support and friendship ... chemotherapeutic agent and in the mobilization and conditioning regimens for blood and marrow transplantation Reviewing the chemistry and pharmacology of cyclophosphamide is crucial for understanding its ... mustard and its mechanism of DNA cross linking Figure represents how phosphoramide mustard forms intrastrand and interstrand cross–links between guanine bases from DNA 23 B Hypothesis and approaches...
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Use of IPs cell derived neural stem cells as a cellular vehicle for glioma and breast cancer therapy
... based cancer gene therapy 28 1.5.5 Future of stem cell based cancer gene therapy 30 Aims and objective 31 Material and methods 33 3.1 Cell culture 33 3.2 Mouse iPSC-derived NSC for glioma therapy ... the organs and draining lymph nodes is very similar to that of human mammary cancer (Pulaski BA and Ostrand-Rosenberg S 1998) 1.3 Gene therapy: the methods for gene transfer Gene therapy is the ... blood and delivery methods are challenges that must be solved for developing effective RNAi reagents for cancer therapy (Kota J et al., 2009) 1.3.4 Immunomodulation approach to cancer gene therapy...
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Delivery of proapoptotic biomolecules and drugs using amphiphilic block copolymer nanoparticles for anti cancer therapy
... actively used in clinics and has become the standard of care for patients with such cancers Following these landmark discoveries, new drugs and potent combinations for cancer treatment have been ... (3 and 6) Herceptin at 200 and 2000 nM, (4 and 7) blank nanoparticle/Herceptin complexes at 200 and 2000 nM Herceptin and (5 and 8) paclitaxel-loaded nanoparticle/Herceptin complexes at 200 and ... nanoparticles, (2 and 5) Herceptin at 200 and 2000 nM, (3 and 6) blank nanoparticle/Herceptin complexes at 200 and 2000 nM Herceptin respectively Cells in (4 and 7) were pretreated with (3 and 6) for 24...
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Báo cáo y học: "Oral Rehydration Therapy for Preoperative Fluid and Electrolyte Management"
... mammary tumors Malignant head and neck tumors Malignant tumors of the stomach Malignant tumors of the respiratory systems Malignant tumors of the urinary and genital organs Malignant gynecological tumors ... Table Eligibility standard for oral rehydration therapy I Patients eligible for oral rehydration therapy (receiving oral rehydration solution) Those who give an informed consent and have not been ... recognized to be safe and clinically effective for the treatment of patients with cholera [9] and is considered to be an effective therapy for the treatment of dehydration and has attracted a great...
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Tài liệu Closing the Gap: Research and Care Imperatives for Adolescents and Young Adults with Cancer docx
... AYAs with or at risk for cancer and ensure excellence in care across the cancer control continuum Develop, evaluate, and disseminate standards of care for AYA cancer patients and survivors to improve ... providers and advocates seeking to achieve a standard of excellence in AYA cancer care Establishing, disseminating, and reinforcing standards of cancer care for AYAs will require the ongoing and concerted ... reduce delays in diagnosis For those diagnosed with cancer and their families, online resources for cancer information, insurance resources, peer support, and other information needs will help...
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Nutrition and cancer: A review of the evidence for an anti-cancer diet pptx
... effects for women undergoing radiation therapy for carcinomas of the uterine cervix [175], for patients undergoing radiation therapy for head and neck cancers [176], and for colorectal cancer ... effect for prostate cancer [136], ovarian cancer [137], and breast cancer [138] Recently Grant found that sunlight was also protective for bladder, endometrial, renal cancer, multiple myeloma, and ... a high fruit and vegetable diet would reduce cancers of the mouth and pharynx, esophagus, lung, stomach, and colon and rectum; evidence of probable risk reduction was found for cancers of the...
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American Cancer Society Guidelines on Nutrition and Physical Activity for Cancer Prevention doc
... safe, enjoyable, and accessible environments for physical activity in schools and workplaces, and for transportation and recreation in communities ACS Guidelines for Nutrition and Physical Activity ... questions about diet and cancer" ) The best advice to reduce the risk of lung cancer is to avoid tobacco use and secondhand smoke and to avoid radon exposure Mouth, throat, and esophagus cancers Tobacco ... activity and lowered risk of kidney cancer The best advice to possibly lower risk for kidney cancer is to stay at a healthy weight and avoid tobacco use Lung cancer More than 85% of lung cancers...
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