using rna interference to create reversible mutant honeybees for memory
Tài liệu Using SQL *Plus to Create Report and Manage Pl/SQL code doc
Ngày tải lên :
17/01/2014, 09:20
... but are used together to perform some tasks, such as to format data in a report and to control command files SQL SQL*Plus Is a language for communicating with the Oracle Server to access data ... to execute commands required Does not require termination characters; commands are immediately executed Uses functions to perform some formatting Uses commands to format data Using SQL*Plus to ... order to restore the original SQL*Plus environment Using SQL*Plus to Create Reports and Manage PL/SQL Code CĆ19 Header CĆ20 Column labels and format Footer Introduction to Oracle: SQL and PL/SQL Using...
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Báo cáo hóa học: "Inhibiting adenoid cystic carcinoma cells growth and metastasis by blocking the expression of ADAM 10 using RNA interference" pdf
Ngày tải lên :
18/06/2014, 16:20
... shRNA vector The ADAM 10 small interfering RNA (siRNA) sequence (CAGUGUGCAUUCAAGUCAA) was designed using the software siRNA Target Designer (Promega, Madison, WI, USA) The preparation of the RNAi ... Immunohistochemistry Immunohistochemistry for ADAM 10 was performed using standard methods Endogenous peroxidase activity Page of 10 was blocked by treatment with 3% hydrogen peroxide in PBS for 30 ... Madison, WI, USA) The preparation of the RNAi vector expressing the human ADAM 10 short hairpin RNA (shRNA) was performed using the pSuper siRNA expression plasmid with the U6 promoter (Oligoengine,...
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Báo cáo sinh học: "Functional genomics of cell morphology using RNA interference: pick your style, broad or deep" doc
Ngày tải lên :
06/08/2014, 18:20
... kinetic information allowed them to detect, for example, that depletion of dynein caused the cells to delay at the metaphase-toanaphase transition, before completing an otherwise normal mitosis The ... proteins lacking RNAi phenotypes opens the door to combinatorial RNAi screens for synthetic interactions and the construction of protein interaction networks (as in yeast [3]) Double RNAi depletions ... fixed cells to reveal effects of protein depletion on cellular shape, the actin cytoskeleton, microtubules or the process of cytokinesis Somma et al [9] focused on eight proteins suspected to participate...
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Báo cáo sinh học: "A functional genomic analysis of cell morphology using RNA interference" pptx
Ngày tải lên :
06/08/2014, 18:20
... viability We used dsRNA to Rho1, a gene required for cytokinesis [10], to optimize conditions for RNAi in a 384-well plate format The addition of 0.3 g Rho1 dsRNA to cells for a minimum of days ... was used for a co-RNAi screen to identify Pten modifiers By screening for dsRNAs that modified the asymmetric microtubule distribution seen in response to Pten RNAi, 20 of the 229 dsRNAs targeting ... already been shown to function in Drosophila cytokinesis [3,10], we identified CG10522 in the RNAi screen as a potential novel Rho1-effector required for cytokinesis [21] RNAi targeting of members...
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REINVENTING STRATEGY Using Strategic Learning to Create and Sustain Breakthrough Performance phần 1 ppsx
Ngày tải lên :
14/08/2014, 05:20
... needs to go from point A to point B in order to succeed This A -to- B approach is at the core of traditional strategy, but in today’s economy it is potentially lethal for corporations One-time, A -to- B ... access to infinite information, sense making—the ability to turn floods of information into real knowledge—has become today’s scarcest and most valuable resource and the key leverage point for value ... revision into shape Without the help of family, the effort would be nearly impossible to sustain Many thanks to my grown-up kids, Chris and Sally, who kept rooting for me all the way For more than...
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REINVENTING STRATEGY Using Strategic Learning to Create and Sustain Breakthrough Performance phần 2 pps
Ngày tải lên :
14/08/2014, 05:20
... flight to London from Virgin.com From Products to Services As customers become empowered by the access to information, and suppliers sell directly to customers, we’re seeing a shift from products to ... jumpers performing graceful leaps over a high bar Tommy went home and told his parents that he wanted to become a high-jump champion “All right,” they replied, “but you’ll have to practice!” So Tommy ... jumping style of the day, and Tommy practiced it diligently every day for months It never occurred to him that there might be some other way to get over the high bar For Tommy, the scissors was high...
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REINVENTING STRATEGY Using Strategic Learning to Create and Sustain Breakthrough Performance phần 3 docx
Ngày tải lên :
14/08/2014, 05:20
... A learning organization might be expected to have its antennae finely tuned to such changes and therefore to be well prepared to recognize and respond to them, shifting strategy nimbly rather than ... ability to these things over and over again, without ever stopping Winning once is not enough; the real challenge is to create an ongoing cycle of learning, focusing, aligning, and winning Motorola ... our competitors to achieve greater value for our customers and superior profits for our firm?” The third, five key priorities, is a list of the most important steps the company must take to turn its...
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REINVENTING STRATEGY Using Strategic Learning to Create and Sustain Breakthrough Performance phần 4 ppsx
Ngày tải lên :
14/08/2014, 05:20
... your customers’ needs be tomorrow?” That’s too big a question for anyone without a crystal ball to answer It can be paralyzing The trick is to break the question into parts: First define today; ... will continue to turn to the authority figure in the white lab coat for advice on what to buy ▼ The authority figure they turn to is now the free-market pharmacist Customer service for the pharmacists ... legendary sales force sold Xerox machines directly to large companies In 1975, Canon, a Japanese photocopier maker, was looking for a way to enter the U.S market Deciding not to go head -to- head with...
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REINVENTING STRATEGY Using Strategic Learning to Create and Sustain Breakthrough Performance phần 5 ppsx
Ngày tải lên :
14/08/2014, 05:20
... differently or better than our competitors to create greater value for our customers and superior profits for ourselves? Greater value for customers can take many forms As the 55 Broad Street, IBM, ... process forces you to the next step: to translate your insights into a breakthrough strategy Med-Surg is using its insights to transform itself from being simply a supplier of consumables to becoming ... big opportunity for IBM’s people was not to approach customers in separate teams, selling lots of different things It was for a unified IBM to provide integrated solutions to its customers— something...
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REINVENTING STRATEGY Using Strategic Learning to Create and Sustain Breakthrough Performance phần 6 doc
Ngày tải lên :
14/08/2014, 05:20
... best to reorganize according to customer group or market sector rather than by function or product category, so as to encourage greater awareness of customer needs and readiness to respond to them ... crucial to you When Cemex, an innovative manufacturer and distributor of cement and other building supplies, wanted to create a computerized information network to speed up its deliveries to builders ... insightful, fascinating stories about African flora and fauna The animals, we discovered, were so accustomed to visitors that Alan was able to drive his open Land Rover filled with tourists within a few...
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REINVENTING STRATEGY Using Strategic Learning to Create and Sustain Breakthrough Performance phần 7 pptx
Ngày tải lên :
14/08/2014, 05:20
... being “good enough” to being the best ▼ From rewarding for longevity to rewarding for performance For Investors ▼ From “We have always done it this way” to “How can it be done ... must change For Customers ▼ From emphasis on regulation to emphasis on competition ▼ From offering what we think customers want to providing what customers value For Employees ▼ ... could transform the company’s culture in support of the new strategy IBM had to be remade into a single, integrated, “silofree” system that would bring a total solution to bear for customers “We...
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REINVENTING STRATEGY Using Strategic Learning to Create and Sustain Breakthrough Performance phần 8 ppsx
Ngày tải lên :
14/08/2014, 05:20
... to this pattern, the matador will plunge the sword into its shoulder blades The moral of the story is that when we are threatened, just like the bull, we tend to retreat to our comfort zone for ... the change effort The process of change thus moves people out of their comfort zones, forcing them to exchange certainty for a sense of uncertainty and danger It is a natural instinct to resist ... leadership It’s not enough for your people to understand the company’s current state (point A) and to be able to envision its future state (point B) The move from A to B always creates an unstable,...
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REINVENTING STRATEGY Using Strategic Learning to Create and Sustain Breakthrough Performance phần 9 ppt
Ngày tải lên :
14/08/2014, 05:20
... powerful way for them to develop greater self-knowledge and to leverage this for personal development They particularly value the fact that it is a simple tool that they can use for themselves ... were in a white-owned grocery store Little Toreaser had a full bladder and asked to use the bathroom Because of her race, the store owner refused Unable to hold it in, Toreaser finally peed on the ... together, and, most important, about his enthusiasm for accepting the job Bob suggested that we would need to redefine the role of president for him to be fully happy in the role, as well as to...
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REINVENTING STRATEGY Using Strategic Learning to Create and Sustain Breakthrough Performance phần 10 docx
Ngày tải lên :
14/08/2014, 05:20
... complicated I try to live my personal and business life using openness, honesty, and integrity as touchstones During the intense pressure of a business turnaround, adhering to these principles ... change, when life seems to bear down with the force of a storm, the player usually rises to the occasion He jumps into the maelstrom, depending on sensibility and intuition to negotiate the currents ... strategic breakthroughs We need to reinvent the way we think about strategy To be valuable in today’s turbulent environment, the goal of strategy must be to provide a process for generating ongoing renewal...
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Reinventing strategy using strategic learning to create and sustain breakthrough performance phần 1 docx
Ngày tải lên :
14/08/2014, 09:21
... needs to go from point A to point B in order to succeed This A -to- B approach is at the core of traditional strategy, but in today’s economy it is potentially lethal for corporations One-time, A -to- B ... access to infinite information, sense making—the ability to turn floods of information into real knowledge—has become today’s scarcest and most valuable resource and the key leverage point for value ... revision into shape Without the help of family, the effort would be nearly impossible to sustain Many thanks to my grown-up kids, Chris and Sally, who kept rooting for me all the way For more than...
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Reinventing strategy using strategic learning to create and sustain breakthrough performance phần 2 doc
Ngày tải lên :
14/08/2014, 09:21
... flight to London from Virgin.com From Products to Services As customers become empowered by the access to information, and suppliers sell directly to customers, we’re seeing a shift from products to ... jumpers performing graceful leaps over a high bar Tommy went home and told his parents that he wanted to become a high-jump champion “All right,” they replied, “but you’ll have to practice!” So Tommy ... jumping style of the day, and Tommy practiced it diligently every day for months It never occurred to him that there might be some other way to get over the high bar For Tommy, the scissors was high...
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Reinventing strategy using strategic learning to create and sustain breakthrough performance phần 3 pdf
Ngày tải lên :
14/08/2014, 09:21
... ability to these things over and over again, without ever stopping Winning once is not enough; the real challenge is to create an ongoing cycle of learning, focusing, aligning, and winning Motorola ... our competitors to achieve greater value for our customers and superior profits for our firm?” The third, five key priorities, is a list of the most important steps the company must take to turn its ... norm in today’s world, and that a conscious effort to recognize, understand, and respond to such change is a vital precursor to strategy creation As noted earlier, it is 71 No Substitute for Insight...
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Reinventing strategy using strategic learning to create and sustain breakthrough performance phần 4 pot
Ngày tải lên :
14/08/2014, 09:21
... your customers’ needs be tomorrow?” That’s too big a question for anyone without a crystal ball to answer It can be paralyzing The trick is to break the question into parts: First define today; ... will continue to turn to the authority figure in the white lab coat for advice on what to buy ▼ The authority figure they turn to is now the free-market pharmacist Customer service for the pharmacists ... legendary sales force sold Xerox machines directly to large companies In 1975, Canon, a Japanese photocopier maker, was looking for a way to enter the U.S market Deciding not to go head -to- head with...
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Reinventing strategy using strategic learning to create and sustain breakthrough performance phần 5 docx
Ngày tải lên :
14/08/2014, 09:21
... differently or better than our competitors to create greater value for our customers and superior profits for ourselves? Greater value for customers can take many forms As the 55 Broad Street, IBM, ... big opportunity for IBM’s people was not to approach customers in separate teams, selling lots of different things It was for a unified IBM to provide integrated solutions to its customers— something ... massively to satisfy them better than anyone else is the one that outperforms its competitors But a winning proposition is one that creates both greater value for your customers and superior profits for...
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Reinventing strategy using strategic learning to create and sustain breakthrough performance phần 6 pptx
Ngày tải lên :
14/08/2014, 09:21
... best to reorganize according to customer group or market sector rather than by function or product category, so as to encourage greater awareness of customer needs and readiness to respond to them ... could transform the company’s culture in support of the new strategy IBM had to be remade into a single, integrated, “silofree” system that would bring a total solution to bear for customers “We ... order to create the new alignment It’s important to be able to say, “Here are some things we’re going to right away in pursuit of our goals—starting first thing Monday morning.” Then go on to list...
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