treatment of rare tumors as secondary tumors

Báo cáo khoa học: "Comparison of conformal and intensity modulated radiation therapy techniques for treatment of pelvic tumors. Analysis of acute toxicity" pdf

Ngày tải lên : 09/08/2014, 09:20

... dose prescribed, to encompass at least 95% of the PTV, ranged from 45 to 50.4 Gy, delivered in 25 to 28 daily fractions in the phase of elective pelvic lymph node treatment Treatment plannings were ... rectal cancer (Table 6) Discussion Use of IMRT in the treatment of pelvic tumors has been increasing throughout the world for more than a decade Our results of acute toxicity among patients in the ... when at least one expected frequency was lower than The Student’s t test was applied to verify association of numerical variables between the CRT and IMRT groups A 5% significance level was considered...

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báo cáo khoa học: "Treatment of malignant tumors of the skull base with multi-session radiosurgery" pdf

Ngày tải lên : 10/08/2014, 22:20

... management of skull base malignancies, both as primary treatment as well as adjuvant treatment, after surgical resection [21-26] However, as with surgery for these tumors, the limitations of this ... patients were classified as having tumors of the skull base, of which 108 were benign Thirty-seven patients had 37 lesions that were classified as malignant skull base tumors Six patients who ... foramen Middle fossa Parasellar Orbit Petroclival Goal of CyberKnife treatment Primary treatment for local disease (%) Secondary treatment (%) Previous treatment Previous craniofacial surgery Previous...

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Effective treatment of solid tumors via cryosurgery

Ngày tải lên : 10/09/2015, 09:09

... Development of the ice front and the boundary of the complete ablation 77 Figure 5.16 Classification of profiles and equivalent ellipsoid: (a) classification of profile in terms of border ... 2.3.2 Vascular stasis The vascular stasis, under the classification of the delayed cell destruction, is a serious slowing or complete cessation of blood or lymph flow through vessels The losses of ... increase of φ while the second term on the left is the net rate of flow of φ out of fluid element The first term on the right side is the rate of change of φ due to diffusion while the last term...

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báo cáo hóa học:" Recent progress towards development of effective systemic chemotherapy for the treatment of malignant brain tumors" docx

Ngày tải lên : 18/06/2014, 15:20

... RG-2 gliomas Gd-G1 thorough Gd-G6 dendrimers extravasate across the BBTB of the microvasculature of small RG-2 gliomas Since small RG-2 gliomas are less vascular than large RG-2 gliomas, there ... trial of surgery in the treatment of single metastases to the brain New England Journal of Medicine 1990, 322:494 Jellinger K, Volc D, Grisold W: Multimodality treatment of malignant gliomas Comparison ... lack of accumulation of the lower Gd-dendrimer generations in the extravascular compartment of small RG-2 gliomas as compared to large RG-2 gliomas (panel A) This is especially evident in the case...

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Báo cáo khoa học: "Surgical strategies for treatment of malignant pancreatic tumors: extended, standard or local surgery?" potx

Ngày tải lên : 09/08/2014, 07:22

... carcinomas in the head of pancreas For those patients with small or low-grade malignant neoplasms as well as small pancreatic metastases located in the mid-portion of pancreas, CP is emerging as a ... effective treatment option for small and/or low-grade malignant neoplasms as well as for pancreatic metastases located in the midportion of the pancreas, since it is associated with a low risk of exocrine ... for PD with ELND is based on the high incidence of intra- and extrapancreatic neural invasion (65%) in pancreatic cancer, as well as the high incidence of lymphnode metastases (30–75%) [5,10,11]...

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Báo cáo khoa học: " Neoadjuvant radiochemotherapy in the treatment of fixed and semi-fixed rectal tumors. Analysis of results and prognostic factors" pptx

Ngày tải lên : 09/08/2014, 10:20

... method of Kaplan and Meier [24] The calculation of OS, DFS and LC was performed from the date of diagnosis to the date of the event Survival was measured from the date of diagnosis to death or last ... T3/T4 and/or N1/N2 tumors [1,2] The strategy of performing preoperative instead of postoperative treatment, has the proven advantages of lower acute toxicity [3-6], lower total dose of radiation needed ... employment of preoperative radiotherapy (RT) combined or not with chemotherapy (CT) has been used in the treatment of rectal cancer for the past two decades and its employ gradually increased as adjuvant...

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Báo cáo khoa học: " CyberKnife® radiosurgery in the treatment of complex skull base tumors: analysis of treatment planning parameters" potx

Ngày tải lên : 09/08/2014, 10:21

... – 18) These tumors were also categorized by histopathology as follows: meningiomas, 13 metastatic tumors, 10 schwannomas, pituitary adenomas, chordoma, sarcomas, and malignant gliomas The median ... categorized by histopathology as follows: 21 meningiomas, metastatic tumors, schwannomas, pituitary adenomas, chordoma, sarcomas, and glioma The median tumor size was 7.27 cc (range: 0.62 – 98.3 ... single measure of how well the treatment dose distribution of a specific radiation treatment plan conforms to the size and shape of the target volume In general, the conformity index of a given...

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Báo cáo khoa học: " Radical stereotactic radiosurgery with real-time tumor motion tracking in the treatment of small peripheral lung tumors" docx

Ngày tải lên : 09/08/2014, 10:21

... therapy Despite treatment one patient died of progressive metastatic disease at months A second single lung metastasis patient died of a myocardial infarction at 11 months without evidence of local ... cancer or single pulmonary metastases were treated Tumors were considered small if the maximum diameter measured less than cm and peripheral if radical treatment was feasible without exceeding conserv- ... response was defined as resolution of the tumor on CT imaging and partial response as a decrease in the tumor volume relative to the treatment planning CT Local and regional tumor recurrence was defined...

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Báo cáo khoa học: The modulation of metal bio-availability as a therapeutic strategy for the treatment of Alzheimer’s disease pptx

Ngày tải lên : 07/03/2014, 10:20

... because of an imbalance in the activity of tau kinases and phosphatases [3] One particular tau kinase pertinent to metal dyshomeostasis in AD is glycogen synthase kinase-3 (GSK3) GSK3 has recently ... result of an aberrant shift in activity of tau kinases and phosphatases [3] Thus, although targeting plaques and NFTs may ameliorate some of the consequences of AD and no doubt lessen the burden of ... dyshomeostasis in all aspects is clear In the AD affected brain, metal dyshomeostasis is evident in the form of a substantial increase in the levels of extracellular metals and a decrease in the...

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Thuốc chống viêm ức chế lipooxygenase và cyclooxygenase dùng dự phòng và điều trị ung th- (LOX an COX - inhibitors as adjunctive therapies in the prevention and treatment of cancer) ppt

Ngày tải lên : 20/03/2014, 03:20

... corticoid Lipomodulin (-) phospholipase phospholipid Acid arachidonic (AA) A2 (-) AA cyclooxygenasse NSAID lipooxygenase 5-HPETE PG endoperoxyd H2 [G2] Prostacyclinsynthetase leucotrien A leucotrien ... làm ngừng chu kỳ tế bào giai đoạn G1 , ức chế tyrosin - kinase, ngăn chặn hoạt tính protein - ras In vitro, quercetin ức chế tyrosin - kinase ngời ung th, ức chế phát triển khối u, làm tăng thời ... Prostacyclinsynthetase leucotrien A leucotrien B prostacyclin (PGl2) PG-synthetase PG sơ cấp (PGE2, D2, P2) TX synthetase TX A2 leucotrien C TX B2 leucotrien D Dới đây, xin điểm qua số chất nguồn...

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EVOLUTION OF THE MOLECULAR BIOLOGY OF BRAIN TUMORS AND THE THERAPEUTIC IMPLICATIONS pdf

Ngày tải lên : 23/03/2014, 10:20

... Gliomas include astrocytomas, glioblastomas, oligodendrogliomas, ependymomas and oth‐ er histological subtypes The most common gliomas are astrocytomas, oligodendrogliomas and ependymomas Since ... grade gliomas include diffuse astrocytomas (fibrillar, gemistio‐ cytic, protoplasmatic, mixed), grade II oligodendrogliomas and oligoastrocytomas Diag‐ nosis of anaplastic glioma is based on the ... Evolution of the Molecular Biology of Brain Tumors and the Therapeutic Implications include anaplastic astrocytoma, anaplastic oligoastrocytoma and anaplastic oligodendro‐ glioma These tumors show...

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báo cáo hóa học:" Identifying alemtuzumab as an anti-myeloid cell antiangiogenic therapy for the treatment of ovarian cancer" pdf

Ngày tải lên : 18/06/2014, 15:20

... 80–100% of each tumor section was photographed Total CD31 stain area, as defined by pixel density and hue, was assessed using Olympus Microsuite Biological Suite software Area of staining was then ... course of the experiment (p < 0.05) (Figure 6A) Treatment of flank tumors was associated with a significant reduction in tumor microvascular density (Figure 6B and 6C) This reduction in microvascular ... and vascular perfusion in control and CD52-treated tumors Magnification and scale bars as indicated C Quantification of microvascular density in anti-CD52 treated tumors and control tumors assessed...

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báo cáo hóa học: " Effect of pioglitazone treatment in a patient with secondary multiple sclerosis" doc

Ngày tải lên : 19/06/2014, 22:20

... interferon β-1b was discontinued because of increased spasticity, and she was not a candidate for glatiramer She had no history of diabetes, cardiovascular, liver or kidney disease When seen in ... increased from 27.3 to 35.9 kg (32%) after 12 months treatment, which was maintained between 34.6 to 36.2 kg throughout an additional 18 months Weight gain was evident as increased muscle mass ... risks, she consented to a trial of pioglitazone, which was initiated at 15 mg daily and increased by 15 mg biweekly to 45 mg Improvement was evident within weeks as increased appetite, cognition and...

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báo cáo hóa học:" A retrospective analysis of clinicopathological and prognostic characteristics of ovarian tumors in the State of Espírito Santo, Brazil" ppt

Ngày tải lên : 20/06/2014, 08:20

... ovarian tumors (adenomas), tumors of low malignant potential (borderline tumors) , or malignant epithelial tumors (adenocarcinomas); being the latest the focus of the present article Whereas most ... to increase the disease treatment success in the cases of platinum-resistant EOC, which can account to as much as 80% of all treated EOC in Brazil (unpublished data) Considering the lack of EOC ... pathologic classification, such as the possible origin of high grade ovarian carcinomas from fallopian tubes and the dualistic model of EOC classification Classically, the origin of EOC has been referred...

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báo cáo hóa học:" Accuracy of 64-multidetector computed tomography in diagnosis of adnexal tumors" ppt

Ngày tải lên : 20/06/2014, 08:20

... triple phase Precontrast scan of the upper abdomen; arterial phase using the Automatic Bolus Tracking System; portal phase yielded with a delay of 60 s after the arterial one The contrast medium ... has been demonstrated that MDCT have high efficacy and accuracy in defining the nature of a pelvic mass and detecting extension of malignant tumors which could be very useful in planning of treatment ... addition, sensitivity of MDCT was 91.1% for detecting ascites (compared to report of the surgical findings), while specificity of it for detecting a malignant cell inside it was 43.3% (compared...

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Báo cáo khoa học: " Application of ventriculoperitoneal shunt as a treatment for hydrocephalus in a dog with syringomyelia and Chiari I malformation" pptx

Ngày tải lên : 07/08/2014, 18:21

... saw sulahpecordyh fo sisongaid A )noitamroflam I iraihC( mulleberec eht la te )worra ,B( )noitamroflam I iraihC( mulleberec eht fo tnecsed )mungam nemarof( laduac dna )daehworra ,B( ,3 ,2C fo ... dna noitamroflam I iraihC eht tey ,aixata rof detneserp taht dna sulahpecordyh htiw dereffus taht god siht fo noitalid ralucirtnev eht deveiler gnitnuhs PV ehT sulahpecordyh gnitaert rof evitanretla ... enileF dna eninaC fo launaM AVASB JN yblO ,RS ttalP 01 7101-5001 ,44 ,9991 yregrusorueN stneitap citamotpmys 463 rof sgnidnif cihpargoidar dna lacinilc :denifeder noitamroflam I iraihC CM reepS ,C...

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Báo cáo khoa học: "Surgical treatment of a rare primary renal carcinoid tumor with liver metastasis" docx

Ngày tải lên : 09/08/2014, 07:21

... will discuss different aspects of this unusual tumor, with emphasis on the treatment of liver metastases ilar densities on CT scan The right ovarian mass was multiloculated, measuring 8.7 cm in diameter ... metastases have been reported as long as years after resection, indicating that long term follow up is needed The treatment of liver metastases from RCT is not well defined due to scarcity of cases ... periods of time even in the presence of tumor spread [5,8] Progression of hepatic metastases is the predominant cause of death in patients with gastrointestinal and other cancers For this reason...

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Báo cáo khoa học: "Giant breast tumors: Surgical management of phyllodes tumors, potential for reconstructive surgery and a review of literature" potx

Ngày tải lên : 09/08/2014, 07:22

... with an obvious mass of the right breast The mass measured 36 × 30 cm at the time of presentation The skin of the breast was blue at the apex of the mass, and the nipple was massively enlarged ... was also conducted Case presentation Case Patient A is a 64 year old white female who presented with a large right breast mass The mass had been present for at least years, and the breast was ... aids in the differentiation of phyllodes tumors from fibroadenomas The majority of these tumors can be managed by simple mastectomy Axillary lymph node metastasis is rare, and dissection should...

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Báo cáo khoa học: " The impact of radiotherapy in the treatment of desmoid tumours. An international survey of 110 patients. A study of the Rare Cancer Network" pptx

Ngày tải lên : 09/08/2014, 10:21

... cellular, often hypocellular ill-defined fascicles of fibroblasts and myofibroblasts lacking nuclear pleomorphism and showing little mitotic activity [7] As fibromatoses not metastasise, surgical ... an assessment of the therapeutic value of radiotherapy in the multimodal treatment of desmoid tumours Patients and methods Patient selection Departments of Surgery and Radiation Oncology of 14 ... progressive disease (7 patients), stable disease (9 patients) and no evidence of disease (94 patients) Figure shows the overall outcome as endpoint with the tumour status as reported at the last follow-up...

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Báo cáo y học: "Local adherent technique for transplanting mesenchymal stem cells as a potential treatment of cartilage defect" pdf

Ngày tải lên : 09/08/2014, 10:23

... number of cells that adhered to the defect; however, the injection of a large number of cells would also increase the number of cells that adhered to the synovium, thereby increasing the risk of ... increased 10 minutes after plating on glass slides Attachment of synovial MSCs within 10 minutes was mediated by these adhesion molecules Their modification may have increased the efficacy of cell ... defect was covered with the periosteum and then chondrocyte suspension was injected into the defect [5] One poor aspect of the autologous chondrocyte transplantation method was the leakage of the...

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