... As compared with embryonic stems cells and bone marrow-derived mesenchymalstem cells, adiposederived mesenchymalstemcells (ADMSCs) have the distinct advantages of being abundant, easy to obtain ... Ratajczak J, Ratajczak MZ: Trafficking of normal stemcells and metastasis of cancer stemcells involve similar mechanisms: pivotal role of the SDF-1-CXCR4 axis StemCells 2005, 23:879-894 Kee HJ, Sohn ... the treatmentof early stages of DCM during disease initiation rather than treatmentof the established condition The purposes of this study were to test the hypothesis that early combined treatment...
... capacity ofcells SVV enhanced the survival of Transplanted MSCs Cells were scattered in a number of colony distributions days after planted At day ~ 9, the bottle was covered with long-spindle cells ... Science Foundation of Fujian Province of China (2008J0282) and by the professorial academic Foundation of Fujian Medical University (JS06077) Page of 10 Author details Department of Neurology, Union ... direct inhibitor of caspase-3 and Biochemistry 2001, 40:1117-1123 Zhu W, Chen J, Cong X, Hu S, Chen X: Hypoxia and serum deprivationinduced apoptosis in mesenchymalstemcellsStemCells 2006, 24:416-425...
... capacity ofcells SVV enhanced the survival of Transplanted MSCs Cells were scattered in a number of colony distributions days after planted At day ~ 9, the bottle was covered with long-spindle cells ... Science Foundation of Fujian Province of China (2008J0282) and by the professorial academic Foundation of Fujian Medical University (JS06077) Page of 10 Author details Department of Neurology, Union ... direct inhibitor of caspase-3 and Biochemistry 2001, 40:1117-1123 Zhu W, Chen J, Cong X, Hu S, Chen X: Hypoxia and serum deprivationinduced apoptosis in mesenchymalstemcellsStemCells 2006, 24:416-425...
... evaluate adipogenic potential of amniotic fluid-derived human mesenchymalstemcellsStemCells Dev 2006, 15:719-726 55 Montaln H, Schichor C, Lah TT: Human mesenchymalstemcells and their use in cell-based ... intracellular detection of a low amount of CD4 in about 20% of MSCs suggests a possible complex regulation of CD4 protein expression in these cells It is noteworthy that this pattern of CD4 expression ... infection of human bone marrow stromal fibroblasts Blood 1990, 76:317-322 40 Wang L, Mondal D, La Russa VF, Agrawal KC: Suppression of clonogenic potential of human bone marrow mesenchymalstem cells...
... 1.5.2 Adult stemcells 10 1.5.2.1 Bone marrow stemcells 10 1.5.2.1.1 Hematopoietic stemcells 11 1.5.2.1.2 Mesenchymalstemcells 11 1.5.3 Bone marrow stem cell-transplantation ... cardiovascular research 1.5.2.1 Bone marrow stemcells There are most common types ofstemcells in bone marrow: (i) hematopoietic stemcells and (ii) mesenchymalstemcells These cell types are believed ... that hematopoietic stemcells may not differentiate into cardiomyocytes45 1.5.2.1.2 MesenchymalstemcellsMesenchymalstemcells (MSCs) encompass a heterogeneous population of undifferentiated, ...
... portion of the cells adhered to the cartilage defect Injection of more cells would increase the number ofcells that adhered to the defect; however, the injection of a large number ofcells would ... Page of 10 (page number not for citation purposes) vial mesenchymalstemcells into cartilage defect Application of low-invasive local adherent technique to transplant synovial mesenchymalstemcells ... 20 21 22 23 24 25 26 Multilineage potential of adult human mesenchymalstemcells Science 1999, 284:143-147 Prockop DJ: Marrow stromal cells as stemcells for nonhematopoietic tissues Science...
... may be another critical target for the treatmentof inflammatory arthritis [11] Mesenchymalstemcells (MSCs) are cellsof stromal origin that can exert profound immunosuppression by modulating ... encouraged a possible use of these cells to modulate autoimmune responses and in the treatmentof autoimmue diseases [12,13] To date, the experience of MSCs in the treatmentof RA is limited to a ... Yao R, Tuan RS: Comparison of proliferative and multilineage differentiation potential of human mesenchymalstemcells derived from umbilical cord and bone marrow StemCells 2007, 25:1384-1392...
... TRANSPLANTATION OFMESENCHYMALSTEMCELLS FOR THE TREATMENTOF PARKINSON’S DISEASE IN A MOUSE MODEL CHAO YIN XIA MD A THESIS SUBMITTED FOR THE DEGREE OF DOCTOR OF PHILOSOPHY DEPARTMENT OF ANATOMY ... Making use of multiple pathways, in vitro expanded MSCs have been shown to suppress the function of a broad range of immune cells, including T cells, B cells, NK cells and antigen-presenting cells ... Genetic background ofstemcells in stem cell transplantation……………93 3.1.1 Characterization of in vitro cultured MSCs……………… …………94 3.1.2 Effect of NFL knockout on the proliferation of MSCs……… …… 95...
... Types ofcells used in bone tissue engineering for osteogenic differentiation 59 2.3.1 Potential ofmesenchymalstemcells (MSCs) for bone healing 60 2.3.2 Potential of bone marrow derived mesenchymal ... inflammatory cells, cellsofmesenchymal origin Chemotactic effect on other inflammatory cells, stimulation of extracellular matrix synthesis, angiogenesis, recruitment of endogenous fibrogenic cells ... Targeted cells: MSCs, osteoprogenitor cells, osteoblasts, chondrocytes Mitogenic for mesenchymalcells and osteoblasts, chemotactic for inflammatory and mesenchymalcells Targeted cells: mesenchymal...
... Study on Treatmentof Femoral Head Necrosis with Arterial Perfusion of Marrow StemCells Chin J Integr Trad West Med 2004,24(11):999-1002 Yan Z, Hang D, Guo C, Chen Z Fate ofmesenchymalstemcells ... application ofstemcells provides promise for the treatmentof ischemic femoral head necrosis When compared with vascular intervention and local drilling for injection, transplantation with stemcells ... intravenous injection ofstemcells as a therapeutic strategy is less investigated in the treatmentof femoral head necrosis Safety is a critical concern of intravenous transplantation of MSCs Whether...
... DR (1999) Multilineage potential of adult human mesenchymalstemcells Science 284, 143–147 Porada CD, Zanjani ED & Almeida-Porad G (2006) Adult mesenchymalstem cells: a pluripotent population ... Kitamura S & Nagaya N (2007) Effect of hypoxia on gene expression of bone marrowderived mesenchymalstemcells and mononuclear cellsStemCells 25, 1166–1177 Li L, Zhang S, Zhang Y, Yu B, Xu Y & Guan ... antifibrotic effect of transplanted mesenchymalstemcells in a rat model of global heart failure Mol Biol Rep 36, 725–731 Li L, Zhang Y, Li Y, Yu B, Xu Y, Zhao S & Guan Z (2008) Mesenchymalstem cell...
... Isolation ofmesenchymalstemcellsof fetal or maternal origin from human placenta StemCells 22, 1338–1345 Bieback K, Kern S, Kluter H & Eichler H (2004) Critical parameters for the isolation ofmesenchymal ... development of in vitro test systems Although primary human hepatocytes are the best source ofcells for such systems, their use for this purpose is limited Transcriptome in hepatic induction of AT-MSCs ... process of hepatic differentiation of AT-MSCs No previous report has demonstrated evidence of transdifferentiation of committed adult stemcells In the case of our study, transdifferentiation,...
... new potential source of pluripotent cells for regenerative medicine The identification of niches of tissue-specific stemcells capable of replacing damaged differentiated cells in the hFTs may ... Prockop D: Mesenchymal stem/ multipotent stromal cells: the state of transdifferentiation and modes of tissue repair – current views StemCells 2007, 25:2896-28902 Valtieri M, Sorrentino A: The mesenchymal ... Discussion The possibility ofusingstemcells for regenerative medicine has opened a new field of investigation to find the best sources for obtaining multipotent stem cells, in particular through...
... marrowderived MSC is the major source ofstemcells in these studies [22,24-27], the therapeutic role of adiposederived mesenchymalstemcells (ADMSCs) in acute IR injury of the lung has not been investigated ... Use of Laboratory Animals (NIH publication No Page of 13 85-23, National Academy Press, Washington, DC, USA, revised 1996) Animal Grouping and Isolation of Adipose-Derived MesenchymalStemCells ... scoring system adopted was as follows: = no detectable crowded area; = 75%-100% of crowded...
... marrow lipid was a consequence of the adipogenesis of marrow mesenchymalstemcells (MSCs) [7] Results of a previous study showed increased number of small size fat cells in the early steroid-associated ... trabecular bone area); fat cells diameter = the total diameter of fat cells in selected field/the number of fat cells in selected field; fat cells area = the area of all fat cells in selected field/(the ... the density of Oil Red Page of (page number not for citation purposes) Journal of Orthopaedic Surgery and Research 2007, 2:15 O positive cells were calculated using Image Pro Plus software (Media...
... Results of Herbert-screw fixation with bone-grafting for the treatmentof nonunion of the scaphoid J Bone Joint Surg Am 1999, 81(1):48-52 Trumble TE, Clarke T, Kreder HJ: Non-union of the scaphoid Treatment ... of compression and distraction at the fracture sites which is thought to improve local micro-circulation [20-24] The aim of this study is to examine the efficacy and safety of SNU treatmentusing ... further soft tissue damage and disruption to the local biology, in less experienced hands A recent systematic review reported union rates of 80% using bone graft without fixation, 85% using bone...
... delivery of CX3CL1 to multiple lung tumors by mesenchymalstemcellsStemCells 2007, 25(7):1618-26 12 Komarova S, Kawakami Y, Stoff-Khalili MA, Curiel DT, Pereboeva L: Mesenchymal progenitor cells ... marrow-derived mesenchymalstemcells in the treatmentof gliomas Cancer Res 2005, 65(8):3307-18 Studeny M, Marini FC, Champlin RE, Zompetta C, Fidler IJ, Andreeff M: Bone marrow-derived mesenchymalstemcells ... phenomenon of MSCs was confirmed in different experimental systems [2,12] Other cell types, such as umbilical cord matrix stemcells (UCMS) [14], neural stemcells [15,16] and endothelial progenitor cells...