... and 20 AAE patients), and 107 pediatric HAE patients with highly individualized therapeutic approaches The majority (73.7%) of adult patients at the center are candidates for sole on-demand therapy ... an as-needed basis Home treatment with plasma derived and recombinant factor VIII and factor IX concentrates is an established therapy in North America since 1975 [13] and is included in the German ... demand treatmentand home therapy of hereditary angioedema in Germany - the Frankfurt experience Allergy, Asthma & Clinical Immunology 2010 6:21 Submit your next manuscript to BioMed Central and...
... remaining breast and tumour bed targets In all cases, the SIB plans with IMRT proved superior quality compared to sequential treatments and authors [15] proposed to consider SIB as standard treatment ... Assurance dosimetric measurements To assess delivery quality and the agreement between calculations and treatment, standardised pre -treatment quality assurance dosimetric measurements were performed ... heart and healthy tissue Tables 1, and summarise numerical findings from DVH, delivery and pre -treatment dosimetry analyses Data are presented as averages over the investigated patients and errors...
... registration system and a longitudinal, doubleentry data capturing system All treatments, including antiretroviral therapy, andtreatment monitoring are provided free of charge and the patients ... number of patients who start and remain on treatment The aim of this analysis is to investigate pre -treatment loss to follow-up and to determine mortality rates and predictors of mortality among ... patients were not able to start ART and accounted for a Togun et al AIDS Research andTherapy 2011, 8:24 http://www.aidsrestherapy.com/content/8/1/24 high pre -treatment mortality rate The fact...
... plots stratified by treatmentand GINA treatment step and analysed in a Cox proportional hazard model with factors including treatment, GINA treatment step and treatment- GINA treatment step at ... including treatment, GINA treatment step, treatment- GINA treatment step interaction and study The number of exacerbations was presented as yearly exacerbation rates by GINA treatment step andtreatment ... treatment step andtreatmentand analysed using a Poisson model with factors including treatment, GINA treatment step, treatment- GINA treatment step interaction and study, and observation time as...
... including direct and overhead capital and recurrent inputs for the base year We obtained the 2004/5 price of drugs and medical supplies from the Pharmaceuticals and Medical Supplies Import and Wholesale ... and 6.6 for non-AIDS and AIDS groups, respectively, under the non-ART condition Our estimates of outpatient visits for non-AIDS and AIDS categories under ART (11.37 and 11.31, respectively, and ... study reported PPY inpatient days of 3.75 and 15.36 for non-AIDS and AIDS stages, respectively, under the non-ART condition; and 1.08 and 2.04 for non-AIDS and AIDS states, respectively, under the...
... Recently, combination treatment of photodynamictherapy (PDT) with dendritic cell (DC)-based immunotherapy also termed photoimmunotherapy has been shown to be an effective anti-tumor treatment In these ... Principal Investigator of the Laboratory of Photodynamic Diagnosis and Treatment, National Cancer Center for her essential and invaluable support Her expert advice and pivotal suggestions were critical ... hypericinphotodynamic therapyand in vivo stimulation of dendritic cells by pNGVL3hFlex plasmid DNA Submitted for publication 1 CHAPTER INTRODUCTION 1.1 PhotodynamicTherapy (PDT) Photodynamictherapy (PDT)...
... Med Sci 2010, with APS We therefore compared single antiplatelet therapyand a combination of antiplatelet and anticoagulation therapy for secondary prevention in ischemic stroke patients with ... with venous and arterial occlusive disease in multiple organs, miscarriages, and livedo reticularis Materials and Methods We focused on the secondary prevention of stroke with APS, and compared ... prevention of stroke with APS, and compared single antiplatelet therapyand a combination of antiplatelet and anticoagulation therapy in ischemic stroke patients with APS The subjects were 20...
... phosphatidylinositol 3-kinase and Hedgehog, and thus affects metabolism, the cell cycle, gene expression, developmental processes and oncogenesis Active GSK3 is indicative of absent WNT-signaling and leads to ... leukemia patients and collected a total of 64 different MLL fusion partners The analyzed MLL fusion alleles were classified according to their occurrence in ALL and AML patients and their putative ... localization and their putative function Twenty-five of them represent nuclear proteins and 33 represent cytosolic proteins; one fusion partner could not be classified With few exceptions (e.g the AF4 and...
... osteotome therapyand restoration with a stock abutment and crown Implant placement with concomitant sinus augmentation therapyand restoration with a stock abutment and crown Sinus augmentation therapy ... regenerative therapy, or the necessity of performing regenerative therapyand placing the implant at a second surgical visit These considerations significantly impact the time and cost of therapyand the ... need for retreatment and the potential damage to the attachment apparati of adjacent teeth This treatment option offers minimal advantages over the aforementioned treatment approach, and no advantages...
... of the aesthetic result, and to point out and discuss the limitations before any treatment is done, thus preventing post -treatment frustrations for both the patient and the dentist It is therefore ... as the occlusal plane, the length and angulation of the teeth, their relation with the upper and lower lips at rest and when the patient smiles, the phonetics and the Fig 15 xxx _ xxx I Fig 16_Pre-op ... understand and visualise the expected aesthetic outcome, with each having its limitations These include diagnostic wax-ups, before and after pictures of other patients, computer imaging and direct...
... fluids used and the waste material from various surface treatment processes are among important factors to be considered 12 Institut Teknologi Bandung MECHANICAL SURFACE TREATMENTAND COATING ... Teknologi Bandung CASE HARDENING AND HARD FACING 26 Institut Teknologi Bandung Case Hardening and Hard Facing Surfaces may be hardened by thermal means in order to improve their frictional and wear ... { Lightweight, thin, and resistant to damage; have good adhesion; and be easily applied to complex external and internal surfaces Several techniques that are suitable and applicable to certain...
... Textile mill products Lumber and wood products Paper and allied products Chemicals and allied products Petroleum and coal products Leather and leather products Primary and metal industry industry ... waste water policy and how does model pretreat‐ 21 22 Waste Water - Treatment Technologies and Recent Analytical Developments ment and post treatment waste water network life cycle, and how does make ... used and reused of all metals The de‐ mand for copper is due to its good strength and fatigue resistance, excellent electrical and thermal conductivities, outstanding resistance to corrosion, and...
... Coordinated Phosphate and Program Derivations 10.9 All-Volatile Treatment Program Chemistries 10.10 Mixed Treatmentand Zero Solids Treatment 10.11 An Outline of Water Treatment for Nuclear Powered ... disciplines and a depth of water treatment problemsolving xxiv Boiler Water Treatment: Principles and Practice experience to overcome technical and operational problems and also add ... Waterside and Steamside Problems: The Basics 4.1 Hot Water and Steam System Cycles 4.2 The Scope of BW Treatmentand Control of Steam/Waterside Chemistry 4.3 Fundamental Steam-Waterside Problems and...
... the case of gene therapy as well Appropriate Candidates for Gene Therapy We now turn to another dimension of ethics issues in gene therapy, namely, who the candidates are for therapy We distinguish ... true in the case of Donald and the gene therapy clinical trial we are considering for his CF? 326 ETHICAL ISSUES IN MOLECULAR MEDICINE AND GENE THERAPY In the case of gene therapy there appear to ... care can make the difference between life and death or 328 ETHICAL ISSUES IN MOLECULAR MEDICINE AND GENE THERAPY the difference between permanent injury and the healing of that injury/restoration...
... genes is up-regulated and of other genes down-regulated (Adapted from Anderson and Anderson, Electrophoresis, 1996.) MOLECULAR MEDICINE AND GENE THERAPY: AN INTRODUCTION gene and the down-regulation ... fuller understanding of biological clocks and the aging process 22 MOLECULAR MEDICINE AND GENE THERAPY: AN INTRODUCTION SUGGESTED READINGS Gene Therapy Anderson WF Human gene therapy Science ... individual patient GENE THERAPYAND MOLECULAR MEDICINE A simple and concise definition of gene therapy (there are many) is the use of any of a collection of approaches for the treatment of human disease...
... neurodegeneration and provide a way to test gene therapy strategies for CNS disorders, injury, or aging 210 COMPONENTS OF CELL AND GENE THERAPY FOR NEUROLOGICAL DISORDERS NEUROTROPHIC FACTORS AND GENE THERAPY ... experience numbness and muscle weakness in the limbs and difficulty with coordination and balance These symptoms can be severe enough to impair walking and standing Speech difficulty, fatigue, and dizziness ... Neurological Disorders and Brain Tumors Humana, Totowa, NJ, 1998 Doering LC Gene therapyand neurodegeneration Clin Neurosci 3:259–321, 1996 Kaplitt MG, Loewy AD Viral Vectors, Gene Therapyand Neuroscience...
... advanced gastric cancer patients [14-16] Oxaliplatin and cisplatin share the similar mechanism, and cause mono-adducts and intra-strand or inter-strand cross-links in the double DNA helix that severely ... leucovorin and oxaliplatin) or XELOX (capecitabine and oxaliplatin) regimen as first-line chemotherapy at Cancer Center of Sun Yat-sen University, and formalin-fixed paraffin-embedded pretreatment ... of the study RZL and HZZ reviewed the IHC slices ZQW and YHL participated in the statistical analysis RHX conceived of the study, and participated in its design and coordination and helped to draft...
... Biological Therapy of Cancer, iSBTc), aims to improve cancer patient outcomes by advancing the science, development and application of biological therapyand immunotherapy The society and its educational ... (105 , 106 and 107 DC per injection) and two different delivery routes (intravenous and intradermal) Immune assessment was performed prior to treatmentand at days 14, 28, 35, 56, and 112 Immune ... specific immune cell subsets and tumor antigens, co-stimulation, negative regulation and tumor cell biology As we improve our understanding of tumor immunology and combine and test various strategies,...
... drugs and/ or photodynamictherapy (PDT) constitute current treatments targeting pathological vascular tissues in tumors and age-related macular degeneration Concern that PDT might induce VEGF and ... widespread treatment for AMD, as is anti-VEGF therapy The latter is a leading treatment for AMD, but requires repeated treatments and a significant investment of time on the part of patient and doctor ... results of randomized clinical trials-TAP report Treatment of age-related macular degeneration with photodynamictherapy (TAP) Study Group Arch Ophthalmol 1999, 117:1329-1345 Photodynamic therapy...