transport across the epithetial barrier
Báo cáo khoa học: Protein transport across the endoplasmic reticulum membrane pdf
... During the synthesis of a multi-spanning membrane protein, the seal would be provided in an alternating manner by either the nascent chain in the pore or, once the chain has left the pore, by the ... 4471–4478 ª 2008 The Author Journal compilation ª 2008 FEBS 4475 Protein transport across the ER membrane T A Rapoport the C-terminus can translocate across the channel, inserting the polypeptide ... folding, the N-terminus can flip across the channel and subsequently exit laterally into the lipid phase When the N-terminus is retained in the cytosol and the polypeptide chain is further elongated,...
- 8
- 310
- 0
báo cáo hóa học: " Lipopolysaccharide-enhanced transcellular transport of HIV-1 across the blood-brain barrier is mediated by luminal microvessel IL-6 and GM-CSF" potx
... act at the luminal, but not the abluminal, endothelial surface to increase the transcellular permeability of BMECs to HIV-1 Furthermore, the results suggest that the LPS-induced increase in the ... markedly increased the concentrations of IL-6 and GM-CSF Therefore, we hypothesized that IL-6 and/or GM-CSF might mediate the LPS-induced increase in HIV-1 transport across the BBB Previously, ... ng/mL) in the luminal side did not increase the phosphorylation of p44/42 MAPK, p38, or JNK 14 Discussion The present study evaluated whether the LPS-enhanced transcellular transport of HIV-1 across...
- 37
- 447
- 0
Báo cáo khoa học: Protein transport in organelles: Protein transport into and across the thylakoid membrane pptx
... with the precursor–receptor complex and the putative translocase is formed (iii) The precursor protein is then transported in a process energized by the DpH across the thylakoid membranes The transported ... from the translocase into the lipid bilayer, where the signal peptide is removed by the TPP and the mature protein is released into the lumen After protein transport, Tha4 dissociates from the ... (iii), the precursor is transported and released from the translocase into the lipid bilayer where the signal peptide is removed and the mature protein is released into the lumen After protein transport, ...
- 10
- 647
- 2
báo cáo hóa học:" Effective transvascular delivery of nanoparticles across the blood-brain tumor barrier into malignant glioma cells" docx
... Gd-dendrimer dose on particle extravasation across the blood-brain tumor barrier The transvascular transport of Gd-G1 through Gd-G8 dendrimers across pores of the BBTB and accumulation within brain ... toxic to the BBTB in addition to the otherwise healthy blood-brain barrier This toxicity is likely due to the introduction of additional positive charge to the Gd-dendrimer surface from the attachment ... [61-64] Therefore, the extravasation of rhodamine labeled nanoparticles [26,65] and other charged nanoparticles [66-69] across the barrier may be from direct charge induced damage to endothelial...
- 15
- 432
- 0
Application of biologically active micelles in drug delivery across the blood brain barrier
... vectors, these two type antibiotics both have poor penetration rates through the BBB As the BBB represents an obstacle for the delivery of these antibiotics from the blood to the brain, therefore, these ... that may use either RMT or CMT to carry the peptide or protein across the cerebral endothelium (Bickel et al., 1994) An example of the drug transport by endogenous BBB transporters is the use of ... compounds There are two physiological barriers that separate the brain from its blood supply and control the entry and exit of endogenous and exogenous compounds One is the BBB and the other is the...
- 219
- 283
- 0
Tài liệu The Effects of Childhood Stress on Health Across the Lifespan pptx
... reported three or more.3 (See table 2.) The Effects of Childhood Stress on Health Across the Lifespan The Effects of Childhood Stress on Health Across the Lifespan Table 1: Prevalence of Individual ... in teach- The Effects of Childhood Stress on Health Across the Lifespan 11 ing children about safety and providing them with skills that may reduce their risk of abuse.18 However, the research ... cortisol can damage the hippocampus, an area of the brain responsible for learning and memory These cognitive deficits can continue into adulthood.1 The National Scientific Council on the Developing...
- 18
- 527
- 0
Tài liệu Diabetes & Women’s Health Across the Life Stages ppt
... because it can affect the health of both a mother and her unborn children With the increasing life span of women and the rapid growth of minority populations in the United States, the number of women ... to develop and then implement the National Public Health Action Plan for Diabetes and Women Much more work is required, but with the monograph, Diabetes and Women’s Health Across the Life Stages: ... gestational diabetes than the national average For instance, the prevalence for Zuni Indian mothers is 15.1 percent and for Navajo Indian women, the rate is 10.4 percent among mothers aged 30-39 years...
- 8
- 370
- 0
Tài liệu Writing Across the Curriculum ppt
... students can quiz themselves or each other as they reference the answers (safely hidden on the other side of the folded sheet) They check back and forth between the questions and answers The right column ... remind their students that they will encounter the words in the text they will read After reading the text, students compare their possible sentences with the actual sentences of the text where the ... Describe the author's point of view • How does the author's attitude shape the way the writer presents the material? • How does the author’s attitude affect the way that the reader responds to the...
- 148
- 1,664
- 0
Comparative Child Well-being across the OECD pot
... achievement around these scores using the ratio of the score at the 90th percentile to the 10th percentile averaged across the three PISA literacy measures The final indicator identifies the proportions ... below the average for the OECD area White values indicate countries around the OECD average The greater the number of white values in a dimension, the closer the clustering of OECD countries across ... Note: The measure is of country inequality in scores, averaged across the three literacy dimensions The measure of inequality used is the ratio of the score at the 90th percentile to that at the...
- 43
- 307
- 0
Diabetes & Women’s Health Across the Life Stages: A Public Health Perspective potx
... gestational diabetes, the primary focus is on the clinical management of the mother’s glycemic status for positive birth outcomes After the birth of the child, systematic follow-up of the mother with gestational ... dictated that the primary focus of women’s health be on their reproductive function, to the neglect of many other aspects of their general health.39 Such thinking was also reflected in the types ... if their social environment does not support the messages The authors conclude that the same social bias that resulted in women’s health historically being viewed primarily in the context of their...
- 222
- 1,035
- 0
Báo cáo khóa học: Identification of residues controlling transport through the yeast aquaglyceroporin Fps1 using a genetic screen ppt
... glycerol transport capacity then wild type even after hyperosmotic shock The apparent rate of glycerol transport is lower for H350L than for the other mutants, which is consistent with the fact ... interact In the models shown (Fig 6), the 226–236 region of the N-loop and 347–356 of the B-loop are in close proximity Residues affected by mutation are then located for the most part in the functionally ... threonine residues in the pore region of Fps1 T256 on the B-loop is conserved across the whole MIP family Fig Structural modelling The B-loop is shown in yellow and the N-loop in green The residues involved...
- 9
- 383
- 0
Guidance on the teaching of writing skills INSET opportunities for teachers of a subjects across the curriculum at Key Stages 2 and 3 docx
... and the skills framework and/or provide guidance for teachers of other subjects across the curriculum? What outcome will there be? Which of these (or other) success criteria are relevant to the ... silently since the writer will often ‘read’ what should be there rather than what is actually on the page Reviewing the text and identifying: • whether or not the text makes sense • whether or not ... reopen the town youth club It was closd over the sumer and so the young pepl and childrin home in the holidays couldnt find anything to They where rude to the peple in the town becaus they was...
- 174
- 616
- 0
Shanghaied - The Economic and Political Implications of the Flow of Information Technology and Investment Across the Taiwan Strait ppt
... remained the weakest link in the Chinese electronics industry, as measured by the Chinese IT industry’s progress toward the global state of the art According to the 10th Five Year Plan, the goal ... narrow the range of political options for the island in the future Opponents of further opening charge that the establishment of the three links would increase Taiwan’s dependence on the mainland ... within the RAND Corporation National Security Research Division (NSRD) NSRD conducts research and analysis for the Office of the Secretary of Defense, the Joint Staff, the Unified Commands, the...
- 218
- 561
- 0
Báo cáo khoa học: cAMP increases mitochondrial cholesterol transport through the induction of arachidonic acid release inside this organelle in Leydig cells pdf
... with the inner mitochondrial membrane [10–13] In the steroidogenic cells, the step that determines the rate of steroid synthesis (the rate-limiting step) is the transport of cholesterol to the ... in the presence of CHX, the fatty acid bypasses the absence of ACS4 but not the absence of StAR Then, the partial inhibition produced by CHX on AA stimulated steroidogenesis was unexpected The ... through the CPT1dependent pathway The specificity of this mechanism to release AA inside the mitochondria is shown by the fact that the content of labeled AA in another organelle such as the nucleus...
- 11
- 430
- 0
First Across the Continent potx
... region; the other streams are the Owl, the Grand, the Cannonball, and the Heart The large town of Stanton, Mercer County, North Dakota, is now situated at the mouth of the Big Knife The passage of the ... refuge They were on the upper side of the ravine near the river, perfectly safe from the rain, and therefore laid down their guns, compass, and other articles which they carried with them The shower ... They expressed their joy at the change in the government; their hopes that we would recommend them to their Great Father (the president), that they might obtain trade and necessaries: they wanted...
- 141
- 442
- 0
Báo cáo khoa học: Transport of the phosphonodipeptide alafosfalin by the H+/peptide cotransporters PEPT1 and PEPT2 in intestinal and renal epithelial cells doc
... reabsorption at the renal epithelium requires both their uptake from the luminal compartment into the cells and their transport (efflux) across the basolateral membranes to Alafosfalin transport by ... pH 6.0 at the apical (1.5 mL) and 7.5 at the basolateral side (2.6 mL) [20] After washing the inserts with buffer, the TranswellÒ chambers were preincubated for 10 and the transepithelial electrical ... H+/peptide transporters (Eur J Biochem 271) 2015 Ó FEBS 2004 the blood side Basolateral peptide transport systems have been described both at the intestine and in the kidney [25, 29–31] Therefore,...
- 6
- 359
- 0
barriers to asset recovery an analysis of the key barriers and recommendations for action
... new law, the onus will lie with the depositor to prove the legal origin of the funds, rather than with the plaintiff to prove that they were illegally obtained (continued next page) 28 I Barriers ... practitioners working in the developed world (the traditional financial centers) and the developing world (typically the victim jurisdictions) to assist the study team in identifying the barriers to asset ... participate in workshops, meeting with the competent practitioners to discuss the study and the impediments they encountered during the course of their work.15 The expertise, practical experience,...
- 200
- 927
- 0
THE ANDES AND THE AMAZON: OR, ACROSS THE CONTINENT OF SOUTH AMERICA docx
... of their journeys in this unknown region Our own Herndon and Gibbon descended the one the Peruvian and the other the Bolivian waters the affluents of the Amazon, beginning their voyage where the ... particular spot on the mud floor, and there is no particular orifice for the exit of the smoke save the chinks in the wall There is not a chimney in the whole republic As the spare room in the establishment ... knowledge of the papal bulls; their morality, in asceticism and devotion to their king; their philosophy, in the subtleties of Aristotle; their history, in the history of the mother country; their geography,...
- 333
- 390
- 0
Across the Plains to California in 1852 Journal of Mrs. Lodisa Frizzell pot
... cattle from the other side of the river, where they CHAPTER III 14 had strayed during the night, but when we found they were across, some of the men went over & watched them, which was the first ... the other waggon recognized of them, belonging to a man from their country, with whom they had intended to travel They asked the man where was the owner of the cows? & why he was driving them ... & by the looks of their loads they not intend to starve Most of the horses, mules & cattle, are the best the states afford; they are indeed beautiful, but I fear some of them will share the fate...
- 30
- 253
- 0
Tìm thêm: xác định các mục tiêu của chương trình khảo sát chương trình đào tạo của các đơn vị đào tạo tại nhật bản xác định thời lượng học về mặt lí thuyết và thực tế tiến hành xây dựng chương trình đào tạo dành cho đối tượng không chuyên ngữ tại việt nam khảo sát thực tế giảng dạy tiếng nhật không chuyên ngữ tại việt nam khảo sát các chương trình đào tạo theo những bộ giáo trình tiêu biểu xác định mức độ đáp ứng về văn hoá và chuyên môn trong ct mở máy động cơ lồng sóc mở máy động cơ rôto dây quấn hệ số công suất cosp fi p2 đặc tuyến hiệu suất h fi p2 đặc tuyến mômen quay m fi p2 đặc tuyến tốc độ rôto n fi p2 đặc tuyến dòng điện stato i1 fi p2 động cơ điện không đồng bộ một pha sự cần thiết phải đầu tư xây dựng nhà máy thông tin liên lạc và các dịch vụ phần 3 giới thiệu nguyên liệu từ bảng 3 1 ta thấy ngoài hai thành phần chủ yếu và chiếm tỷ lệ cao nhất là tinh bột và cacbonhydrat trong hạt gạo tẻ còn chứa đường cellulose hemicellulose chỉ tiêu chất lượng theo chất lượng phẩm chất sản phẩm khô từ gạo của bộ y tế năm 2008