tools for the analysis of spatial data
An investigation into the use of gaussian processes for the analysis of microarray data
... the data in term of its distribution The value of the score is high if the two means of the classes are very different and the data of each class are crowded near the mean of the data Fisher Score ... method, i.e the outputs of the training examples are known and the purpose is to predict the output of new example In most of the cases, the outputs are either of two classes Hence, the task is ... encouraging results Except for the Leukaemia dataset, the results of the other three datasets show that the methodology perform competitively, compared with the results of Shevade and Keerthi (2002)...
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Báo cáo y học: "ChIPOTle: a user-friendly tool for the analysis of ChIP-chip data" docx
... distribution with a mean of zero The variance of the observations is estimated by the average sum of the squared negative log ratios Under the null hypothesis, the distribution of the average log2 ratio ... width of portion of the peak above the significance cutoff, 'array density' of the peak, and the P value for that peak The array density value is defined as the average number of arrayed elements ... in the ROC curves by the low true-positive rate at the extreme left of the plot (b) The 95% confidence interval for the AUC for each analysis technique was estimated by bootstrap resampling of...
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Tài liệu Báo cáo khoa học: A systems biology approach for the analysis of carbohydrate dynamics during acclimation to low temperature in Arabidopsis thaliana doc
... assessment of the trajectory of interconversion rates as a function of time of cold exposure, (b) comparison of the magnitudes of the various interconversion rates, and (c) lineup of the accessions ... photosynthesis, gas exchange of plants was measured by infrared gas analysis Measurements were performed during the first h 508 of the light phase, representing the time period of photosynthetic ... terms of the absolute values but also in the progression of the acclimation process This is an important outcome, as it allows estimation of the impact of different metabolic responses on the improvement...
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Tài liệu Báo cáo khoa học: a-Conotoxins as tools for the elucidation of structure and function of neuronal nicotinic acetylcholine receptor subtypes doc
... systems is therefore essential to prove the utility of the oocyte system and the validity of correlations based on the characterization of oocyte-expressed subunit combinations Nevertheless, the activity ... tissues The analysis of the DNA of different Conus species has already revealed a large number of a-conotoxin sequences [45] and the identification of further specific nAChR ligands is likely The advantage ... nanouseful information on the binding mode of a-conotoxins molar affinity (EC50 0.5–8 nM) and high selectivity for [53,58] and the activation states of the nAChR At the Table Comparison of a common...
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TECHNIQUES FOR THE ANALYSIS OF ORGANIC CHEMECALS BY INDUCTIVELY COUPLED PLASMA MASS SPECTROMETRY (ICP-MS) pptx
... used, rather than pure oxygen, avoiding the use of highly flammable or explosive gases in the laboratory The oxygen is added either in the spray chamber or using a T-connector before the torch ... suffer from the formation of new “cluster” species observed with the use of more reactive gases such as ammonia The performance of CRC based ICP-MS instruments cannot, however, match the detection ... analysis of the organic solvent is the preferred method of analysis, either untreated or simply diluted in a suitable solvent Direct organic solvent analysis demands some...
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Báo cáo khoa học: "SOFTWARE TOOLS FOR THE ENVIRONMENT OF A COMPUTER AIDED TRANSLATION SYSTEM" pptx
... the translator This data base is composed of dictionaries, "formats" and "procedures" of the analysis, transfer and synthesis phases (the conventional phases of a CAT system) For any given source ... two factors : the dispersal of information and the obscurity of the coding In ARIANE-78, the lexical data base may reside on much more 50 files, for a given pair of language Figure Screen Display ... help the translator and improve his effeciency VISULEX offers two levels of detail At the first level, the information is presented by using only the comments associated with the codes found At the...
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Báo cáo khoa học: Affinity purification-mass spectrometry Powerful tools for the characterization of protein complexes ppt
... Biochem 270) 571 Analysis of protein complexes Within the scope of this review, we will focus on summarizing the current technical state of the art for the biochemical retrieval of associated proteins ... affinity-based methods The common theme of these is the use of an inherent interaction (affinity) of two biomolecules If one of the molecules is immobilized on a solid support, the interacting molecule ... from the column is another technical problem that could become serious in the later MS analysis Large amounts of antibodies present in the eluate might mask the presence of proteins of the purified...
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Báo cáo lâm nghiệp: "An approach for the analysis of vegetation spectra using non-linear mixed modeling of truncated power spectra" pdf
... reflectance in the visible yet reduced reflectance in the NIR and SWIR regions of the spectrum Analysis of vegetation spectra 519 Figure Summary of F-ratio tests of significance of the variance of the ... colinearity, the approach should also reduce the dimensions of the data with a minimum of information loss It must accomplish this reduction without losing the ability to interpret the results Transforming ... each of the seven balsam fir groups were withheld from the model-fitting data and classified as outlined above to one of the seven groups Similar, the last two foliage samples in each of the three...
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Báo cáo lâm nghiệp: "of morphological characters and molecular markers for the analysis of hybridization in sessile and pedunculate oak" pps
... Morphological analysis In the second case of the figure, the heterozygote deficit (f) must be considered The frequency of the phenotype A+ is the sum of the frequency of the genotype P : +/+ All of the ... means of the comparison of the RAPD marker frequencies of a subsampling of these progenies and of the adult population Analysis of the morphological characters MATERIALS AND METHODS Sampling The ... classified in the space of the other species over the analyses Molecular analyses The allele frequencies of the RAPD loci in the adult trees of the stand, calculated according to the two hypotheses:...
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Báo cáo y học: "In vitro model for the analysis of synovial fibroblast-mediated degradation of intact cartilage" pptx
... established the modified, present form of the model, performed the real-time PCR, the immunohistochemistry and the respective data analyses and wrote the manuscript D Pohlers performed some of the experiments ... validity of the new model for the analysis of the mechanisms of cartilage destruction by SFB Both MMP-1, capable of cleaving intact collagen [44], and MMP-3, responsible for the cleavage of other extracellular ... higher amount of damage than the respective monocultures Collagen synthesis In view of an amplification of the potential net loss of collagen from the cartilage matrix, the synthesis of collagen...
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báo cáo khoa học: "Numerical techniques for the analysis of polygenes sampled from natural populations" ppsx
... on the other hand, is homozygous for the « high » allele (A All of the l ) l progeny from the standard cross have inherited the A allele from the father and are, therefore, heterozygous A The ... outline the sequence of analysis using a hypothetical example The hypothetical standard for this example is homozygous for « - » alleles (M ATHER & JINKS, 1982) and has low expression of the character ... they make no assumption about the presence of clusters in the data Clusters, if present, will be depicted On the other hand, if a more or less continuous distribution of points is the case, then...
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báo cáo khoa học: " Systems medicine and the integration of bioinformatic tools for the diagnosis of Alzheimer’s disease" doc
... encompass only informatics and statistics; for example, it includes the development of tools not only for storing and mining the data, but also modeling of the data in the context of disease pathophysiology ... diagnostic and therapeutic avenues Bioinformatics tools enabling a systems medicine approach to AD Many tools are available for mining of heterogeneous biological data, although the focus of such tools ... affect the mobility of Aβ peptides, including dynamics of their self-assembly Lipidomics tools are now available for detailed studies of molecular lipids in cells and biofluids [48] Molecular profiling,...
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Báo cáo y học: "A novel human ex vivo model for the analysis of molecular events during lung cancer chemotherapy" pptx
... covered the clinical part EV was involved in the design of the study and histomorphological evaluation TG conceived the study and was involved in the evaluation of the data as well as the writing of ... responsible for the surgical part of the investigation CM and ARR carried out the LIFE/DEAD-assay and 2-photon microscopy PZ was involved in the design of the study, evaluation of the results ... 60% in the native tumor tissues, shifting the mean value above the corresponding mean value of the untreated cultured tumor samples Therefore, the median values are also given in Table The general...
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Báo cáo sinh học: " Longitudinal random effects models for genetic analysis of binary data with application to mastitis in dairy cattle" pdf
... the number of episodes of infection or the timing of the episodes Furthermore, environmental conditions fluctuate in the course of lactation A longitudinal analysis of such data gives flexibility ... test-day j for cow i and γi = (γ0i , γ1i , γ2i ) a × vector of the Wilmink’s parameters for animal i At the second stage of the hierarchy, a mixed linear model was imposed to the parameters of the Wilmink ... lactation Given the small amount of information in our data set, we did not test the effect of applying a random regression for the permanent effect The same pattern was observed for heritability...
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Báo cáo y học: "Statistical methods and software for the analysis of highthroughput reverse genetic assays using flow cytometry readouts" pps
... with the technical aspects of data import and management, and refer the interested reader to the documentation of the software package prada for a thorough discussion of these [19] Selection of ... impression of the distribution of the data when the number of observations is large and the points become too dense (Figure 8a) This is a problem for cytometry data with often more than 20,000 data ... used for the different assays, each specifically measuring the phenotype of interest In the case of cell proliferation, the antibody detected the incorporation of the thymidine analog BrdU into the...
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Using biological networks and gene expression profiles for the analysis of diseases
... Profiles for the Analysis of Diseases LIM JUNLIANG KEVIN (B.Comp (Hons.), NUS) A DOCTORAL THESIS SUBMITTED FOR THE DEGREE OF DOCTOR OF PHILOSOPHY DEPARTMENT OF COMPUTER SCIENCE NATIONAL UNIVERSITY OF ... swaps the class labels of the original data, preserving the proportions of the classes, and the modified t-statistic is computed using this permuted set for each gene The same ordering can be performed ... set of genes of the same size as the pathway being evaluated The p-value assigned for a pathway is the proportion of permutations that have aggregated scores higher than the score computed for the...
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Development of methods to improve sensitivity and portability of capillary electrophoresis for the analysis of stabilizers and drugs 1
... β-CD-NH2 and the backward movement of the neutral sample partitioned in the micelles of sodium dodecyl sulfate (SDS) Stability of the inclusion complexes formed between the carrier and the solute ... displacer plug was introduced before sample injection to reduce the length of the concentrated sample zone and increase the peak height by slowing down the forward movement of the neutral sample associated ... With the high separation efficiency, high resolution and portability, CE has been proven a powerful method for the studies of many groups of compounds The improvement of sensitivity and the miniaturization...
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Development of methods to improve sensitivity and portability of capillary electrophoresis for the analysis of stabilizers and drugs 2
... Where, Δp: the pressure difference; r: the inner diameter of the capillary; 20 t: the injection time; η: the viscosity of the buffer; L: the total length of the capillary In the case of all hydrodynamic ... macromolecules The transport of the solutes through the 15 capillary is based on the charge of the macromolecules, but the separation is dependent on the molecular size Besides the gel forming medium, other ... than the EOF as their velocity direction is the same as that of the EOF, so very rapid analysis times are therefore achieved with positively charged compounds The neutral compounds move at the...
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Capillary and microchip electrophoresis for the analysis of small biomolecules
... applied, the mobile layer of buffer cations migrates towards the cathode As it does, it drags the bulk of the buffer solution along with it and thereby generating the EOF The strength of this EOF is ... even after it is deformed by the application of external forces Hence, soft lithography technique is commonly utilized for the microfabrication of such microchips35 The design of the fluid circuit ... this will raise the buffer’s viscosity and thereby lowering the strength of the EOF The EOF, thus, determines the times at which the charged compounds migrate out When a strong EOF is generated...
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