tissue specific autonomic responses to reflex inputs
Báo cáo y học: "Differential expression, function and response to inflammatory stimuli of 11β-hydroxysteroid dehydrogenase type 1 in human fibroblasts: a mechanism for tissue-specific regulation of inflammation" pps
... with specific tissues [31] and inflammatory responses [29] Glucocorticoids are powerful endogenous modulators of inflammatory signal transduction [3], and because their effects vary between tissues ... expression and function are also subject to significant tissue- specific variations Differential expression of 11β-HSD1 did not appear to be due to underlying inflammatory disease in donor RA patients, ... GR, glucocorticoid receptor; H6PDH, hexose-6-phosphate dehydrogenase; TNF, tumour necrosis factor treated with proinflammatory cytokines, but our data suggest that tissue- specific variations in...
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Báo cáo y học: "Genome mapping and expression analyses of human intronic noncoding RNAs reveal tissue-specific patterns and enrichment in genes related to regulation of transcription" pot
... the top 50% of intensities, over 83% to 90% of intronic transcription events are specific to one strand Even when 100% of the expressed transcripts were considered, 63% to 79% were found to be ... expressed in each of the three tissues Considering only the top 10% most highly expressed sense and antisense TIN transcripts (the top 10%) in each tissue, only 1% to 5% were detected simultaneously ... map to genes related to regulation of transcription Most highly expressed TIN transcripts map to genes related to regulation of transcription TIN RNA expression data from three different human tissues...
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An asthma allergen specific animal model for the study of responses to dust mite allergen induced asthma
... factor with an important role in Th17 differentiation, Fogli et al (2013) demonstrated that IL-17 was able to drive neutrophilic lung inflammatory responses that lead to symptoms similar to that ... recognizing the invader, come into play T helper cells produce a number of inflammatory cytokines that orchestrate the immune response to the invader, while cytotoxic T cells actively kill infected ... of Tregs to suppress the immune response lies in several different mechanism: they secrete inhibitory cytokines such as IL-10 and TGF-β, express inhibitory molecules such as they cytotoxic T lymphocyte...
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An investigation into some types of verbal responses to questions in English and Vietnamese conversation
... the United States? (Q) B: Thats too easy (C to Q) A: No it isnt (C to C) B: George Washington (A to Q) In this study, we try to isolate some types of responses to questions which have the illocutionary ... responding to question They are: direct and indirect responses, refusals to answer, challenges to the presupposition of question, responses to implicit meaning of the question and some special responses: ... job; we are working together and have to go on business trips Overall, both English and Vietnamese males and females pay more attention to give direct responses to questions To avoid giving the...
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food neophobia among the finns and related responses to familiar and unfamiliar foods
... willingness to try genetically modi®ed tomato, although it was clearly of plant origin Responses to LoR chocolate bar and to FlavSavR tomato suggest that the FNS scores may predict responses to unfamiliar ... Finland); and FlavSavR tomato which was claimed to be genetically modi®ed These three foods were included to examine how speci®cally the food neophobia scale re¯ects consumer responses to ethnic vs other ... two factors (Table 1) The ®rst is related to the interest (or disinterest) in trying new and ethnic foods The second appears to relate to a general concern vs carelessness with respect to trying...
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A comparative analysis of institutions, national policies, and cooperative responses to floods in Asia
... human responses to floods IFA aggregates and compares results of country-based research in order to further explore the problem How to strengthen capacities and performance of institutions to reduce ... how to effectively shape human institutional responses to the risk of natural disasters with a special focus on floods In Asia, human vulnerability to natural disasters and, particularly, to those ... the state to come to the rescue In more wealthy countries like Japan state guarantees have allowed significant entry by the private sector into insuring against flood disasters (Kitamoto et al...
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Checkpoint and Coordinated Cellular Responses to DNA Damage
... of ATR to chromatin Similarly, in Xenopus extracts RPA is also needed for the recruitment of ATR to DNA lesions generated by etoposide (Costanzo et al 2003), a DNA topoisomerase II inhibitor This ... mediators, including Brca1 and Claspin, have been shown to possess affinities to DNA (Paull et al 2001; Sar et al 2004) Although the DNA-binding activities of these mediators might contribute to ... DNA lesions In addition to the phosphorylation of histone H2AX, other histone modifications are also detected in the vicinity of DSBs For example, histone H4 is shown to be acetylated at DSBs...
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A study on english and vietnamese responses to compliments
... divided into two categories, Person -to- Person Compliment Responses (PP-CRs, hereafter) and Compliment Responses to a third person (3rd P-CRs, hereafter) 4.2.1 Person -to- Person Compliment Responses ... With the purpose to make an investigation into syntactic and pragmatic features of verbal responses to compliments in their contrast in English and Vietnamese, this study aims to describe and ... an investigation into this field should be carried out to contribute to a better process of teaching and learning English Carrying out a contrastive study on verbal responses to compliments in...
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Tài liệu Module 12: Designing Responses to Security Incidents doc
... use an audit policy to audit specifically for security threats To design an audit policy, use a framework to help you determine what to audit, how to audit, and when and how to review the data ... you need to track later Globally auditing all events will cause event logs to grow to an unmanageable size An audit statement helps you define what events to monitor, the level of detail to audit, ... then type your answer to Ashley’s questions Click Send to save your answers to a folder on your desktop Discuss your answers as a class 28 Module 12: Designing Responses to Security Incidents...
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Blackwell Publishing Ltd Reproductive and physiological responses to simulated climate warming for four subalpine species pot
... all reproductive tissues; R(flower+fruit), total net respiration from all reproductive tissues; Pnet, annual net photosynthesis of the plant; TNC, total nonstructural carbohydrate stored in and available ... apparently different responses to IR forcing, and employed an integrative process model to investigate one potential mechanism for altered reproduction in relation to www.newphytologist.org © The ... assimilation Photosynthetically active radiation temperature Leaf -to- air vapor pressure deficit © The Authors (2006) Journal compilation © New Phytologist (2006) www.newphytologist.org New Phytologist...
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Báo cáo khoa học: Staying on message: design principles for controlling nonspecific responses to siRNA pdf
... central roles in nonspecific responses to siRNA in vivo TLR7 and TLR8 are thought to mediate the majority of both inflammatory cytokine and interferon-dominated immune responses to siRNA in vivo [25,52], ... stimulation observed may be due to enhanced trafficking of siRNA to endosomes and the cytoplasm, and therefore to enhanced interaction with endosomal and cytoplasmic receptors It is also possible that ... However, because siRNA must be released into the cytoplasm in order for them to be incorporated into RISC, any siRNA motifs that activate cytoplasmic receptors would still induce immune activation...
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Health policy responses to the f inancial crisis in Europe doc
... to the goal of efficiency The purpose of trying to increase efficiency in the health sector is to maximize outcomes for a given level of public resources devoted to health care Governments’ responses ... nurses compared to doctors (Laurant et al., 2005) 4.4.3 Payments to providers In response to the crisis several countries have reduced the tariffs (i.e prices) paid to providers (Estonia, Ireland, ... countries seem to have used the crisis to try to increase efficiency, particularly in the hospital and pharmaceutical sectors, although little has been done to enhance value through policies to improve...
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Policy Responses to the Global Economic Crisis in Africa pot
... have some scope within the WTO to apply safeguard mechanisms to provide, amongst others, credit to domestic firms and to engage in government procurement programmes to stimulate the domestic economy ... designed to help countries cope with the effects of the crisis, the international community needs to be more alert to country-level differences This is where it is important to be able to identify ... measures, to be undertaken by both the international community and African countries, include: ■ Monitoring the impact of the crisis; ■ Restoring confidence in, and continuing to monitor and regulate...
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Báo cáo khoa học: Cotton GhMPK2 is involved in multiple signaling pathways and mediates defense responses to pathogen infection and oxidative stress doc
... viologen (MV) The ectopic expression of GhMPK2 in transgenic tobacco plants led to enhanced resistance to fungi and viruses This resistance was most probably attributable to elevated constitutive ... transgenic and wild-type tobacco plants Transcriptional levels of these genes in transgenic tobacco are indicated relative to the level of wild-type tobacco, taken as 1, referring to the transcripts ... transgenic tobacco plants (A) Symptoms of the leaves, stems and roots of the tobacco plants inoculated with F oxysporum at 10 days postinoculation (B) Symptoms of the leaves and stems of tobacco...
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The Temporal Pattern of Mortality Responses to Air Pollution: A Multicity Assessment of Mortality Displacement potx
... 15 M) in Rome The Paris data were assumed to be equivalent to PM10 in this study Rome data were converted to PM10 using a site -specific conversion factor based on colocated measurements.24 In ... which can distort the association with air pollution Therefore, we chose a smoothing parameter for time to reduce the residuals to white noise Sometimes it was necessary to introduce autoregressive ... death and day before death † Exposure up to 40 days before death, subject to constraints to keep the estimated effect from changing too much from one lag to the next The constraint was a cubic...
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Báo cáo khoa học: Plant oxylipins: Plant responses to 12-oxo-phytodienoic acid are governed by its specific structural and functional properties ppt
... appropriate tool with which to regulate transcription factor activity, as shown for nuclear factor kappa-light-chain-enhancer of activated B cells (NF-jB), c-Jun or peroxisome proliferator-activated ... work on phytoprostanes allow for hypotheses in which bioactive plant RES act as Michael acceptors, thereby adding not only to GSH, but also directly to enzymes and transcription factors OPDA: ... seemingly similar to the regulation by OPDA and pathogens [63] Moreover, a major part of these responses is shown to be dependent on TGACG motif-binding factor (TGA) transcription factors Thus, a...
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Báo cáo khoa học: Transcriptional responses to glucose at different glycolytic rates in Saccharomyces cerevisiae ppt
... source [34] (Fig 1) In order to follow glucoseinduced responses, the yeast strains were grown in the presence of 1% (v/v) ethanol to a D610 of 1, pulsed with glucose to a final concentration of ... continued to catabolize glucose (Fig 1) The HXTnull strain continued consuming ethanol, leaving glucose unconsumed Short-term response to glucose addition Using QPCR we monitored the response to glucose ... HXT-null strain To monitor the long-term glucose response, the four strains were grown in the presence of a high (5%) concentration of glucose to a D610 of 1.0 A sample was shifted to a low (0.05%)...
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Báo cáo Y học: Matrilysin (matrix metalloprotease-7) cleaves membrane-bound annexin II and enhances binding of tissue-type plasminogen activator to cancer cell surfaces docx
... tPA binds to some membrane proteins, including annexin II [41] The binding of tPA or urokinase-type plasminogen activator to the membrane receptors greatly increases plasminogen activator activity ... (Qiagen, Tokyo) according to the manufacturer’s protocol Two or three days later, the cells were used for experiments Phase separation of membrane-associated molecules in Triton X-114 solution To separate ... and subjected to immunoblotting for tPA (top panel) and enolase as an internal loading control (center panel) Annexin II released into the culture supernatant by the matrilysin/serotonin treatment...
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Programmatic Responses to Refugees’ Reproductive Health Needs potx
... reported that due to the lack of sanitary napkins, they have resorted to sitting over an open flame in order to slow or temporarily cease their 182 menstrual bleeding to enable them to work for short ... system parallel to local facilities Local referral hospitals should be identified and supported to enable them to respond to comprehensive emergency obstetric needs of refugee women and to reinforce ... a plan to upgrade camp health facilities to provide basic maternity care Within each area, one clinic was selected and equipped to remain open 24 hours a day to handle emergencies and to transport...
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