thymomas and thymic carcinomas

Báo cáo y học: "Sequence analysis of the Epstein-Barr virus (EBV) BRLF1 gene in nasopharyngeal and gastric carcinomas" docx

... studies and drafted the manuscript YW and YC participated parts of the studies and writing YZJ was responsible for the collection of specimens used in this study ZFS and BL provided consultation and ... China (NSFC 30740068 and NSFC 30970157); the Natural Science Foundation of Shandong Province, China (Y2008C90); Science and Technology of Qingdao City, China (08-2-3-7-hz and 08-2-1-4-nsh) Author ... potentially interesting and needs more functional studies Further investigation in extended areas and EBV associated diseases will enhance our understanding of BRLF1 gene polymorphism and their association...

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Báo cáo hóa học: " Decreased level of recent thymic emigrants in CD4+ and CD8+T cells from CML patients" pdf

Danh mục: Hóa học - Dầu khí

... design and data management SXG and SHC performed the real-time PCR, QSY and LJY performed the seminested PCR, XLW and BL performed the statistical analysis, XD collected samples All authors read and ... from all 48 cases, and CD4+ and CD8+ T cells from 19 cases TRBV sjTRECs were determined in PBMCs, CD4+ and CD8+ T Quantitative detection of δRec-ψJα sjTRECs in DNA from PBMCs and sorted CD4+ or ... cells were counted T cells sorting The CD4+ and CD8+ T cells from 19 CML cases and 17 healthy individuals were sorted using CD4 and CD8 monoclonal antibody and MACS® Magnetic Cell sorting technique...

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Báo cáo sinh học: " Toll-like receptor 4 single-nucleotide polymorphisms Asp299Gly and Thr399Ile in head and neck squamous cell carcinomas" potx

Danh mục: Điện - Điện tử

... and GL provided study materials or patients HSB, PS, JG, AB, CW and GL participated in collection and assembly of data CP and AS participated in data analysis and interpretation CB, HSB, AB and ... Informatics, Biometry and Epidemiology, University of Duisburg Essen, Hufelandstrasse 55, 45122 Essen, Germany Authors’ contributions CB designed the study and participated in data analysis and interpretation ... Germany) at 95°C for 30 s, 61°C for 30 s and 72°C for 30 s Digestion with BccI at 37°C (New England Biolabs Inc., Ipswich, MA, USA) and results in fragments of 77 bp and 63 bp for the G-allele vs 140...

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báo cáo hóa học:" Toll-like receptor 4 single-nucleotide polymorphisms Asp299Gly and Thr399Ile in head and neck squamous cell carcinomas" doc

Danh mục: Hóa học - Dầu khí

... and GL provided study materials or patients HSB, PS, JG, AB, CW and GL participated in collection and assembly of data CP and AS participated in data analysis and interpretation CB, HSB, AB and ... Informatics, Biometry and Epidemiology, University of Duisburg Essen, Hufelandstrasse 55, 45122 Essen, Germany Authors’ contributions CB designed the study and participated in data analysis and interpretation ... Germany) at 95°C for 30 s, 61°C for 30 s and 72°C for 30 s Digestion with BccI at 37°C (New England Biolabs Inc., Ipswich, MA, USA) and results in fragments of 77 bp and 63 bp for the G-allele vs 140...

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báo cáo hóa học:" Neuronal transcription factor Brn-3a(l) is over expressed in high-grade ovarian carcinomas and tumor cells from ascites of patients with advanced-stage ovarian cancer" ppt

Danh mục: Hóa học - Dầu khí

... acquisition, analysis and interpretation of data, drafting and revising the manuscript AL and CBR assisted with experiments, interpretation of data and manuscript preparation JFK and MAQ assisted ... domain of Brn-3a and on both long and short forms of the molecule [10] Thus, Brn-3a short and long have distinct functions in neuronal cells, Brn-3a(l) induces Bcl-2 expression and protects neurons ... ascites tumor cells and ovarian cancer cell lines consistent with novel distinct role of this factor in the progression and recurrence of this disease Methods and materials Antibodies and reagents Mouse...

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Chapter 090. Bladder and Renal Cell Carcinomas (Part 1) ppt

Danh mục: Sức khỏe giới tính

... increase in both squamous and transitional cell carcinomas of the bladder Pathology Clinical subtypes are grouped into three categories: 75% are superficial, 20% invade muscle, and 5% are metastatic ... squamous cancers with keratinization constitute 3%, adenocarcinomas 2%, and small cell tumors (with paraneoplastic syndromes)

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Chapter 090. Bladder and Renal Cell Carcinomas (Part 2) docx

Danh mục: Sức khỏe giới tính

... T1, and T2 or greater lesions, tumors with alterations in p53, p21, and/ or RB have a higher probability of recurrence, metastasis, and death from disease Clinical Presentation, Diagnosis, and ... Selective catheterization and visualization of the upper tracts should be performed if the cytology is positive and no disease is visible in the bladder Ultrasonography, CT, and/ or MRI may help to ... tumors should be resected, and a sample of the muscle underlying the tumor should be obtained to assess the depth of invasion Normalappearing areas are biopsied at random to ensure no field defect...

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Chapter 090. Bladder and Renal Cell Carcinomas (Part 3) docx

Danh mục: Sức khỏe giới tính

... surgery that requires appropriate preoperative evaluation and management The procedure involves removal of the bladder and pelvic lymph nodes and creation of a conduit or reservoir for urinary flow ... conservative management (e.g., due to multicentric and frequent recurrences resistant to intravesical instillations); high-grade tumors (T1G3) associated with CIS; and bladder symptoms, such as frequency ... be achieved, there is no CIS in other sites, and the bladder capacity is adequate after the tumor has been removed This occurs in 5–10% of cases Carcinomas in the ureter or in the renal pelvis...

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Chapter 090. Bladder and Renal Cell Carcinomas (Part 4) potx

Danh mục: Sức khỏe giới tính

... vinblastine, doxorubicin, and cisplatin (M-VAC); cisplatin and paclitaxel (PT); gemcitabine and cisplatin (GC); or gemcitabine, paclitaxel, and cisplatin (GTC) M-VAC was considered standard, but the toxicities ... the Renal Pelvis and Ureter About 2500 cases of renal pelvis and ureter cancer occur each year; nearly all are transitional cell carcinomas similar to bladder cancer in biology and appearance This ... a comparative trial of M-VAC versus GC that showed less neutropenia and fever, and less mucositis for the GC regimen Anemia and thrombocytopenia were more common with GC GTC is not more effective...

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Chapter 090. Bladder and Renal Cell Carcinomas (Part 5) pdf

Danh mục: Sức khỏe giới tính

... HippelLindau (VHL) syndrome, which predisposes to renal cell carcinomas, retinal hemangioma, hemangioblastoma of the spinal cord and cerebellum, and pheochromocytoma Roughly 35% of individuals with VHL ... tumors tend to be bilateral and multifocal Chromophobic tumors have a more indolent clinical course, and oncocytomas are considered benign neoplasms In contrast, Bellini duct carcinomas, which are ... (PDGF), and a number of other hypoxia-inducible proteins Inactivation of VHL leads to overexpression of these agonists of the VEGF and PDGF receptors, which promote tumor angiogenesis and tumor...

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Chapter 090. Bladder and Renal Cell Carcinomas (Part 6) pptx

Danh mục: Sức khỏe giới tính

... sedimentation rate 55 The standard evaluation of patients with suspected renal cell tumors includes a CT scan of the abdomen and pelvis, chest radiograph, urine analysis, and urine cytology If metastatic ... syndrome), and acquired dysfibrinogenemia Erythrocytosis is noted at presentation in only about 3% of patients Anemia, a sign of advanced disease, is more common Table 90-4 Signs and Symptoms ... or abscesses), and other primary or metastatic cancers Other malignancies that may involve the kidney include transitional cell carcinoma of the renal pelvis, sarcoma, lymphoma, and Wilms' tumor...

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Chapter 090. Bladder and Renal Cell Carcinomas (Part 7) pptx

Danh mục: Sức khỏe giới tính

... corrected calcium, and abnormal lactate dehydrogenase were poor prognostic factors Patients with zero, one or two, and three or more factors had a median survival of 24, 12, and months, respectively ... two orally administered antiangiogenic agents, sorafenib and sunitinib, that inhibited receptor tyrosine kinase signaling through the VEGF and PDGF receptors Both showed efficacy as second-line ... carcinoma A randomized phase trial comparing sunitinib to IFN-α showed superior efficacy for sunitinib with an acceptable safety profile The trial resulted in a change in the standard first-line...

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Báo cáo toán học: "Expressions of EphA2 and EphrinA-1 in early squamous cell cervical carcinomas and their relation to prognosis" pps

Danh mục: Báo cáo khoa học

... expression of EphA2 and EphrinA-1 in a series of 217 early squamous cell cervical carcinomas and to identify predictive markers of the clinical outcome for these patients Materials and methods Patient ... South of Norway (S-06381a), The Social- and Health Directorate (06/4509 and 06/4417) and The Data Inspectorate (06/01467-3) approved the study Table Ephrin A-1 and EphA2 immunostaining in relation ... association between the expressed proteins and between protein expression and clinicopathological parameters Using the method described by Kaplan and Meier, disease-free and disease-specific survival curves...

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Báo cáo khoa học: "Lymphangiosis carcinomatosa in squamous cell carcinomas of larynx and hypopharynx – value of conventional evaluation and additional immunohistochemical staining of D2-40" ppsx

Danh mục: Báo cáo khoa học

... correlated with nodal involvement, stage and size of the tumor, and survival Sensitivity and specificity were calculated Data were processed by Microsoft Excel and SPSS for descriptive statistic values, ... diameter was investigated For standard staining and immunohistochemistry serially prepared sections were examined In large tumors, especially areas of the lateral and deep tumor borders (front ... lymphatic vessel invasion in SCC of larynx and hypopharynx with special respect to predict the risk of nodal metastases and individual prognosis Materials and methods 119 cases (between 1996 up to...

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Báo cáo khoa học: "Invasive micropapillary carcinomas arising 42 years after augmentation mammoplasty: A case report and literature review" potx

Danh mục: Báo cáo khoa học

... number of mitoses and nuclear pleomorphism) were 3, and 2, respectively Immunohistochemically, the tumors were estrogen receptor (ER) and progesterone receptor (PgR) positive and C-erbB-2 negative ... siliconoma and the tumor correa) Ultrasonography of the left breast showing the siliconoma (white triangle) and the tumor (black triangle) b) Microscopic appearance of the siliconoma and the tumor ... of carcinoma and/ or autoimmune disorders and few studies indicate that those who have undergone mammoplasty are at increased risk of developing breast cancer However, in Europe and the United...

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Báo cáo khoa học: " Ipsilateral irradiation for well lateralized carcinomas of the oral cavity and oropharynx: results on tumor control and xerostomia" pot

Danh mục: Báo cáo khoa học

... clinical examination, by both the head and neck surgeon and the radiation oncologist, endoscopy and CT scan of the head and neck region A chest X-ray or chest CT and blood test were performed to rule ... years, and once yearly until 10 years Radiation oncologists and head and neck surgeons performed a clinical examination A head and neck CT or MRI, examination under general anesthesia and/ or ... contralateral parotid and part of the contralateral submandibular gland Certainly, the salivary function can be further preserved using ipsilateral IMRT because the major salivary glands and some part...

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Báo cáo khoa học: " Inverse planned stereotactic intensity modulated radiotherapy (IMRT) in the treatment of incompletely and completely resected adenoid cystic carcinomas of the head and neck: initial clinical results and toxicity of treatment" potx

Danh mục: Báo cáo khoa học

... Adenoid cystic carcinomas of the head and neck are a unique kind of tumour deriving from cells of the major and minor salivary glands, they account for 25% of all malignant salivary gland tumours ... performed the patient study and treatment planning Statistical analysis and patient follow-up was done by AJ, MWM, SN and PH Manuscript was drafted by PH, MWM, JD All authors read and approved final manuscript ... intensity modulated radiation therapy and inverse treatment planning for tumors of the head and neck region: clinical implementation of the step and shoot approach and first clinical results Radiother...

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Báo cáo y học: "Thymic function and T cell parameters in a natural human experimental model of seasonal infectious diseases and nutritional burden" potx

Danh mục: Báo cáo khoa học

... neutrophil and macrophage function; and vitamin D status is associated with respiratory illness and risk of TB[13,14] Thymic atrophy characterises diet induced malnutrition in mice;[15] and the ... severe thymic atrophy[17] In humans, postmortem studies show thymic involution in the severely malnourished[18] Furthermore, cytokines including IL-7 and IL-2 which are important for thymic and ... beyond thymic output and T cell numbers, and the extensive CD8 + TCRVb repertoire distortions in the population indicated more severe immune challenges than was evident from the thymic output and...

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Báo cáo y học: "En bloc Extended Total Thymectomy and Extrapleural Pneumonectomy in Masaoka stage IVA Thymomas" ppsx

Danh mục: Báo cáo khoa học

... the study, and participated in its design and coordination and helped to draft and revise the manuscript for important intellectual content HCY had full access to all of the data and takes responsibility ... after surgery Patient 5, and The most recent three patients that had mediastinal thymomas with pleural dissemination at initial presentation were enrolled and received a standardized multidisciplinary ... M, Ambrogi MC, Duranti L, Basolo F, Fontanini G, Angeletti CA, Mussi A: Advanced stage thymomas and thymic carcinomas: results of multimodality treatments Ann Thorac Surg 2005, 79:1840-4 Lee HS,...

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Báo cáo y học: "The role of a pseudocapsula in thymic epithelial tumors: outcome and correlation with established prognostic parameters. Results of a 20-year single centre retrospective analysis" pptx

Danh mục: Báo cáo khoa học

... simplification classifying thymomas into different groups; A-B2 on the one side and B3 and C thymomas on the other side [3] We used this simplification for statistical analysis and presentation of clinical ... regime and clinical outcome Thymomas vary in its biological behaviour; also biology of this malignancy is still not fully understood Two major classifications for thymomas are important and help ... critical review of surgical records and pathology reports Further more, R-, Nand M-Status was classified in addition to a local infiltration of vessels and pericardium and the presence of a pseudocapsula...

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