thuỷ phân liên kết 1 6 glucosidase của glycogen
CÂU HỎI TRẮC NGHIỆM HÓA HỌC VÀ CHUYỂN HÓA GLUCID pptx
Ngày tải lên :
23/03/2014, 07:20
... glucid Block A Thuỷ phân mạch thẳng glycogen B Thuỷ phân liên kết α1 -6 Glucosidase glycogen C Enzym gắn nhánh glycogen D Enzym đồng phân glycogen E Enzym cắt nhánh glycogen 1 76 Amylo 1 -6 Glucosidase ... Glucosidase enzym A Thuỷ phân mạch thẳng glycogen B Thuỷ phân liên kết α1 -6 Glucosidase glycogen C Enzym gắn nhánh glycogen D Enzym đồng phân glycogen E Enzym chuyển nhánh glycogen 177 Enzym tiêu ... Tạo liên kết α 1 -6 glycogen 193 Amylo1 -6 glucosidase có đặc điểm sau đây: A Không có B Hoạt hoá phosphorylase không hoạt động gan C Tạo liên kết α 1-4 glycogen D Enzym cắt nhánh glycogen E Tạo liên...
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Báo cáo y học: "yrosine kinase – Role and significance in Cancer"
Ngày tải lên :
03/11/2012, 09:57
... 1998 17: 58 96- 5904 66 Dudley, DT., Pang, L., Decker, SJ., Bridges, AJ., and Saltiel, AR A Synthetic Inhibitor of the MitogenActivated Protein Kinase Cascade PNAS USA, 1995 92: 768 6- 768 9 67 Boehm, ... Opin Chem Biol., 1999 3:459- 465 62 Hanahan, D., and Folkman, J Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis Cell, 19 96 86: 353- 364 63 Kerbel, RS A cancer therapy ... throughout the body [61 , 62 , 63 ] VEGF (Flt-1) receptor tyrosine kinase mediated mitogenesis of human endothelial cells and growth of multiple tumor types is inhibited by SU54 16 [64 ] PD173074 is a...
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Protein Kinases Involved in Mitotic Spindle Checkpoint Regulation
Ngày tải lên :
25/10/2013, 21:20
... Cell Biol 161 : 267 –280 Dobles M, Liberal V, Scott ML, Benezra R, Sorger PK (2000) Chromosome missegregation and apoptosis in mice lacking the mitotic checkpoint protein Mad2 Cell 101 :63 5 64 5 Fang ... Genet 36: 1159–1 161 Hardwick KG, Weiss E, Luca FC, Winey M, Murray AW (19 96) Activation of the budding yeast spindle assembly checkpoint without mitotic spindle disruption Science 273:953–9 56 Harper ... complex Mol Biol Cell 13:755– 766 Farr KA, Hoyt MA (1998) Bub1p kinase activates the Saccharomyces cerevisiae spindle assembly checkpoint Mol Cell Biol 18:2738–2747 1 06 I Hoffmann Fischer MG, Heeger...
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Tài liệu Báo cáo khoa học: TEC family kinases in health and disease – loss-of-function of BTK and ITK and the gain-of-function fusions ITK–SYK and BTK–SYK pptx
Ngày tải lên :
14/02/2014, 18:20
... of the TEC kinases and disease 57 58 59 60 61 62 63 64 65 66 67 68 69 70 European Society for Immunodeficiencies (Casanova JL & Kutukculer N, eds), p 56 Topkon Congress Services, Kadikoy-Istanbul, ... EMBO J 15, 62 41 62 50 Franke TF, Kaplan DR, Cantley LC & Toker A (1997) Direct regulation of the Akt proto-oncogene product by phosphatidylinositol-3,4-bisphosphate Science 275, 66 5 66 8 Sable CL, ... Haematologica 96, 472–4 76 Joseph RE, Min L & Andreotti AH (2007) The linker between SH2 and kinase domains positively regulates catalysis of the Tec family kinases Biochemistry 46, 5455–5 462 FEBS Journal...
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Tài liệu Báo cáo khoa học: Interaction between very-KIND Ras guanine exchange factor and microtubule-associated protein 2, and its role in dendrite growth – structure and function of the second kinase noncatalytic C-lobe domain docx
Ngày tải lên :
14/02/2014, 19:20
... CD2 1099 Inter- 60 0 250 767 150 934 IB: -v-KIND E F CD2-1 CD2-1-1 63 4 CD2-1-2 66 7 CD2-1-3 701 CD2-1-4 CD2-1-5 735 CD2-1 -6 702 CD2-1-7 66 8 CD2-1-8 63 5 CD2-1 -6- 1 702 CD2-1 -6- 2 CD2-1 -6- 3 Interaction ... acids 60 0– 767 ) derivatives: CD2-1-1 (amino acids 60 0 63 4), CD2-1-2 (amino acids 60 0 66 7), CD2-1-3 (amino acids 60 0–701), CD2-1-4 (amino acids 60 0–734), CD2-1-5 (amino acids 735– 767 ), CD2-1 -6 (amino ... CD2-1 -6 (amino acids 702– 767 ), CD2-1-7 (amino acids 66 8– 767 ), CD2-1-8 (amino acids 63 5– 767 ), CD2-1 -6- 1 (amino acids 702–735), CD2-1 -6- 2 (amino acids 702–744) and CD2-1 -6- 3 (amino acids 702– 755)...
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Tài liệu Báo cáo khoa học: The Arabidopsis protein kinase Pto-interacting 1-4 is a common target of the oxidative signal-inducible 1 and mitogen-activated protein kinases docx
Ngày tải lên :
14/02/2014, 19:20
... MPK6 in vitro and with MPK6 in vivo To investigate further the interaction between OXI1 ⁄ PTI1-4 and MPK3 ⁄ MPK6 proteins, we tested whether FEBS Journal 278 (2011) 11 26 11 36 ª 2011 The Authors Journal ... (Fig 6D) On the other hand, the MPK6 protein was present in root extracts after immunoprecipitation with the anti-MPK6 IgG These results indicate that PTI1-4 forms a protein complex with MPK6 in ... 789–795 36 Benjamins R, Ampudia CS, Hooykaas PJ & Offringa R (2003) PINOID-mediated signaling involves calciumbinding proteins Plant Physiol 132, 162 3– 163 0 37 James P, Halladay J & Craig EA (19 96) ...
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Tài liệu Báo cáo khoa học: EGF receptor in relation to tumor development: molecular basis of responsiveness of cancer cells to EGFR-targeting tyrosine kinase inhibitors docx
Ngày tải lên :
16/02/2014, 09:20
... Biol Chem 269 , 35 96 360 4 75 Xing J, Ginty DD & Greenberg ME (19 96) Coupling of the RAS-MAPK pathway to gene activation by RSK2, a growth factor-regulated CREB kinase Science 273, 959– 963 76 Lin YW, ... EGFR mutations PLoS Med 4, 166 9– 167 9 Cragg MS, Kuroda J, Puthalakath H, Huang DC & Strasser A (2007) Gefitinib-induced killing of NSCLC FEBS Journal 277 (2010) 3 16 3 26 ª 2009 The Authors Journal ... PLoS Med 4, 165 5– 166 8 Xiang J, Chao DT & Korsmeyer SJ (19 96) BAXinduced cell death may not require interleukin betaconverting enzyme-like proteases Proc Natl Acad Sci USA 93, 14559–14 563 Meijerink...
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Tài liệu Báo cáo khoa học: Loose interaction between glyceraldehyde-3-phosphate dehydrogenase and phosphoglycerate kinase revealed by fluorescence resonance energy transfer–fluorescence lifetime imaging microscopy in living cells doc
Ngày tải lên :
16/02/2014, 09:20
... (%) 0.05a 0.07a 0.05c 0.05c 0.06b 0.12b 62 .9 58.8 56. 6 56. 2 68 .8 58.9 3 .62 3.27 3. 46 3.39 3. 56 3.31 n s2 (ns) ± ± ± ± ± ± 0.05a 0.14a 0.09c 0.11c 0.06b 0.11b v2 6 6 1.0–1.2 0.8–1.0 1.0–1.1 1.0–1.1 ... Citrine–GAPDH PGK 36. 8 39 .6 39.9 41.4 1.41 1. 06 1.43 1.29 ± ± ± ± a2 (%) 0.21a 0.09a,b 0.20 0.05b 63 .2 60 .4 60 .1 58 .6 3.59 3.13 3 .63 3.44 n s2 (ns) ± ± ± ± 0.13a 0.07a,b 0.19 0.10b v2 6 6 1.0–1.1 1.0–1.1 ... a.u 550 60 0 nm IRF P5C n = 6) P5C + G5Y (n = 6) PGK IRF G5Y (n = 6) P5C + G5Y (n = 6) 0.1 10 a.a B Cerulean Citrine 2.0 0.1 Time/ns Intensity / a.u Intensity / a.u 550 60 0 nm IRF P7C n = 6) P7C...
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Tài liệu Báo cáo khoa học: Myristoylation of the dual-specificity phosphatase c-JUN N-terminal kinase (JNK) stimulatory phosphatase 1 is necessary for its activation of JNK signaling and apoptosis pdf
Ngày tải lên :
16/02/2014, 14:20
... 522.33 5 86. 33 OxM 408.19 344.19 268 .23 382.27 439.29 Myr-Gly Asn Gly 579. 26 465 .21 515. 26 401.21 MH+ MH+- 8 46. 48 63 6.37 700.37 Asn Lys 261 . 16 147.11 CH3SOH 782.47 b3 439.29 y2 261 . 16 y5CH SOH ... monoisotopic mass of 8 46. 48 was selected for sequencing b4CH3SOH 522.34 y4y2-NH3 244.14 y1 147.11 CH3SOH y3- 401.22 CH3SOH 783.48 b4 5 86. 33 344.20 b1 268 .23 847.47 y5 579. 26 b2 382.28 y4 465 .21 b5 700.37 ... oxidized and inactivated in vivo Methods 35, 28– 36, doi:S10 46- 2023(04)00 168 -9 [pii] 10.10 16/ j.ymeth.2004.07.005 Shevchenko A, Wilm M, Vorm O & Mann M (19 96) Mass spectrometric sequencing of proteins...
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Tài liệu Báo cáo khoa học: Crystal structures of the regulatory subunit of Thr-sensitive aspartate kinase fromThermus thermophilus pdf
Ngày tải lên :
18/02/2014, 08:20
... (2.49–2.40) 364 163 ⁄ 19 507 9.5 ( 46. 5) 30.8 (6. 0) 100.0 (100.0) PF-NW12 0.9794 P4332 2.40 (2.49–2.40) 365 251 ⁄ 19 539 9.5 ( 46. 3) 30.2 (5.8) 100.0 (100.0) PF-NW12 0. 963 0 P4332 2.40 (2.49–2.40) 364 474 ... Residues (%) 102 12 28 15 11 16 21 38 13 63 .4 7.45 17.4 9.32 6. 83 9.94 3.73 3.11 5.59 13.0 3.73 3.11 0 .62 5.59 23 .6 5.59 8.07 4.35 1. 86 3.11 0 .62 88 14 18 19 14 10 34 10 11 6 50 14 15 51.2 8.14 10.5 ... (70) 22 291 (68 ) ˚ Hydrophilic (A2) 63 89 (21) 67 09 (21) DG 283 261 Cavity volume 41.4 110.1 ˚ ˚ (probe 1.4 A) (A3) D (Tt)Cg) )978 (2) )320 (0) 22 )68 .7 FEBS Journal 2 76 (2009) 3124–31 36 ª 2009 The...
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Tài liệu Báo cáo khoa học: Phosphorylation of hormone-sensitive lipase by protein kinase A in vitro promotes an increase in its hydrophobic surface area ppt
Ngày tải lên :
18/02/2014, 11:20
... PKA [8–10] In rat HSL, Ser 563 , Ser659 and Ser 660 are phosphorylated by PKA in vitro as well as in vivo [9] Of these, Ser659 and Ser 660 , corresponding to Ser649 and Ser650 in human HSL, have been ... Bradford MM (19 76) A rapid and sensitive method for the quantitation of microgram quantities of protein FEBS Journal 2 76 (2009) 4752–4 762 ª 2009 The Authors Journal compilation ª 2009 FEBS 4 761 PKA phosphorylation ... immunogold electron microscopy (Fig 6E,F) When vesicles mixed with nonphosphorylated HSL (Fig 6E) were compared with vesicles mixed with phosphorylated HSL (Fig 6F), 23% of the imaged vesicles contained...
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Tài liệu Báo cáo khoa học: Mitogen-activated protein kinase phosphatase-1 modulated JNK activation is critical for apoptosis induced by inhibitor of epidermal growth factor receptor-tyrosine kinase pdf
Ngày tải lên :
18/02/2014, 13:20
... senescence Nat Cell Biol 6, 215–2 26 1 264 26 Camps M, Nichols A & Arkinstall S (2000) Dual specificity phosphatases: a gene family for control of MAP kinase function FASEB J 14, 6 16 27 Keyse SM (2000) ... of HER2-overexpressing tumor cells Cancer Res 61 , 7184–7188 FEBS Journal 2 76 (2009) 1255–1 265 ª 2009 The Authors Journal compilation ª 2009 FEBS 1 263 JNK activation is critical for AG1478-induced ... Cell Biol 12, 1 86 192 28 Farooq A & Zhou MM (2004) Structure and regulation of MAPK phosphatases Cell Signal 16, 769 –779 29 Chen YR, Wang X, Templeton D, Davis RJ & Tan TH (19 96) The role of c-Jun...
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Tài liệu Báo cáo khoa học: Hypoxia downregulates farnesoid X receptor via a hypoxia-inducible factor-independent but p38 mitogen-activated protein kinase-dependent pathway doc
Ngày tải lên :
18/02/2014, 13:20
... mixtures Hs00231 968 , Hs00184824, Hs00187 067 , Hs002 267 7, Hs0089 268 1 and 4310881E were used, respectively TaqMan assay mixture Hs00231 968 can detect all of the four isoforms of FXR [60 ] Amplification ... transcriptional response to hypoxia Cancer Res 63 , 61 30 61 34 63 Elvidge GP, Glenny L, Appelhoff RJ, Ratcliffe PJ, Ragoussis J & Gleadle JM (20 06) Concordant regulation of gene expression by hypoxia ... et al 27 28 29 30 31 32 33 34 35 36 37 enhance the activity of the insulin receptor and glycogen synthase in primary rodent hepatocytes Hepatology 39, 4 56 463 Ono K & Han J (2000) The p38 signal...
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Tài liệu Báo cáo khoa học: Mitochondrial targeting of intact CYP2B1 and CYP2E1 and N-terminal truncated CYP1A1 proteins in Saccharomyces cerevisiae ) role of protein kinase A in the mitochondrial targeting of CYP2E1 pdf
Ngày tải lên :
18/02/2014, 16:20
... Chem 274, 66 17 66 25 Taylor SW, Fahy E & Ghosh SS (2003) Global organellar proteomics Trends Biotechnol 21, 82–88 Neupert W (1997) Protein import into mitochondria Annu Rev Biochem 66 , 863 –917 Pfanner ... Journal 274 (2007) 461 5– 463 0 ª 2007 University of Pennsylvania Journal compilation ª 2007 FEBS +3 kDa B /1 A1 +5 /1 A DH FR 1A 1A 1 A 81 62 kDa 81 62 47 kDa 81 62 47 35 35 35 25 16 47 2E Mitochondrial ... as described by Anandatheerthavarada et al [6] FEBS Journal 274 (2007) 461 5– 463 0 ª 2007 University of Pennsylvania Journal compilation ª 2007 FEBS 462 7 Mitochondrial targeting of rat CYPs in yeast...
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Tài liệu Báo cáo khoa học: Protein kinase CK2 activates the atypical Rio1p kinase and promotes its cell-cycle phase-dependent degradation in yeast pdf
Ngày tải lên :
18/02/2014, 16:20
... phosphorylation sites are numbered consecutively (1 6) FEBS Journal 274 (2007) 465 4– 466 7 ª 2007 The Authors Journal compilation ª 2007 FEBS 465 5 Rio1 protein kinase is regulated by CK2 M Angermayr ... Aky2p antibodies derived from hen egg yolk FEBS Journal 274 (2007) 465 4– 466 7 ª 2007 The Authors Journal compilation ª 2007 FEBS 466 1 Rio1 protein kinase is regulated by CK2 M Angermayr et al pursued, ... G1-specific proteins (e.g Sic1p, Cln1p, FEBS Journal 274 (2007) 465 4– 466 7 ª 2007 The Authors Journal compilation ª 2007 FEBS 466 3 Rio1 protein kinase is regulated by CK2 M Angermayr et al Cln2p)...
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Tài liệu Báo cáo khoa học: Structural and functional investigations of Ureaplasma parvum UMP kinase – a potential antibacterial drug target ppt
Ngày tải lên :
18/02/2014, 16:20
... α7 β4 α5 Parameter P21 a, 79.8 b, 96. 6 c, 96. 3 b, 105.8 One hexamer 33.4–2.5 (2 .64 ) 99.9 (99.9) 11.7 (41.5) 11.4 (3.1) 3.8 182 62 3 48 558 ESRF, ID14 eh4 0.9 76 100 23.3 28.5 Content of asymmetric ... 274 (2007) 64 03 64 14 ª 2007 The Authors Journal compilation ª 2007 FEBS 64 07 UMP kinase from Ureaplasma parvum L Egeblad-Welin et al A A B D77 B F133 G63 G 56 D70 G57 G50 N140 R55 R62 T131 T138 ... 274 (2007) 64 03 64 14 ª 2007 The Authors Journal compilation ª 2007 FEBS 64 09 UMP kinase from Ureaplasma parvum L Egeblad-Welin et al 60 50 F133N V/(u/mg) 40 30 F133A 20 10 0 200 400 60 0 [UMP]/µM...
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Tài liệu Báo cáo khoa học: Dual P2Y12 receptor signaling in thrombin-stimulated platelets – involvement of phosphoinositide 3-kinase b but not c isoform in Ca2+ mobilization and procoagulant activity pdf
Ngày tải lên :
18/02/2014, 16:20
... thrombin) Thrombin Vehicle AR-C AR-C + MRS2179 Vehicle AR-C AR-C + MRS2179 64 6 591 64 8 767 60 3 565 40173 265 13 29 064 54149 25 762 23744 Thrombin + ADP that long-term signaling via P2Y12 receptors is ... *P < 0.05 (n = 4 6) 374 ± ± ± ± ± ± 38 (100%) 69 (91%)* 142 (100%) 131 (119%) 103 (93%)* 131 (87%)* ± ± ± ± ± ± 3032 266 0 4098 7418 2784 3421 (100%) (66 %)* (72%)** (135%)* (64 %)* (59%)* This ... Cc2 signaling pathway controls 15 16 thrombus formation induced by collagen and tissue factor in vitro and in vivo Arterioscler Thromb Vasc Biol 25, 267 3– 267 8 Mangin P, Yap CL, Nonne C, Sturgeon...
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Tài liệu Báo cáo khoa học: An alternative transcript from the death-associated protein kinase 1 locus encoding a small protein selectively mediates membrane blebbing pdf
Ngày tải lên :
18/02/2014, 17:20
... Differ 11, 63 1 64 4 Kuo JC, Wang WJ, Yao CC, Wu PR & Chen RH (20 06) The tumor suppressor DAPK inhibits cell motility by blocking the integrin-mediated polarity pathway J Cell Biol 172, 61 9 63 1 10 ... formation of stress fibers in response to oxidative stress J Cell Sci 120, 366 6– 367 7 Charras GT, Hu CK, Coughlin M & Mitchison TJ (20 06) Reassembly of contractile actin cortex in cell blebs J Cell Biol ... funded by grants 301 ⁄ 05 ⁄ 04 16 and 301 ⁄ 08 ⁄ 1 468 from GACR and grant LC 060 35 T Hupp is funded by grants from Cancer Research UK References Bialik S & Kimchi A (20 06) The death-associated protein...
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Tài liệu Báo cáo khoa học: Phosphorylation of cyclin dependent kinase 4 on tyrosine 17 is mediated by Src family kinases pptx
Ngày tải lên :
18/02/2014, 18:20
... effects of PD 0183812 A potent inhibitor of the cyclin D-dependent kinases CDK4 and CDK6 J Biol Chem 2 76, 166 17– 166 23 FEBS Journal 275 (2008) 3099–3109 ª 2008 The Institute of Cancer Research: Royal ... Chen LB & Kufe D (19 96) Nuclear signaling induced by ionizing radiation involves colocalization of the activated p 56 ⁄ p53lyn tyrosine kinase with p34cdc2 Cancer Res 56, 361 7– 362 1 32 Yuan ZM, Huang ... antibodies as indicated (C) HCT1 16 cells were transfected with Flag-tagged CDK4 or CDK4Y17F and treated with either vehicle (dimethylsulfoxide), PP2 (10 lM), SU 665 6 (10 lM) or sodium orthovanadate...
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Tài liệu Báo cáo khoa học: Role of ceramide kinase in peroxisome proliferatoractivated receptor beta-induced cell survival of mouse keratinocytes ppt
Ngày tải lên :
18/02/2014, 18:20
... vesicles J Biol Chem 264 , 14354–14 360 Liang H, Yao N, Song JT, Luo S, Lu H & Greenberg JT (2003) Ceramides modulate programmed cell death in plants Genes Dev 17, 263 6– 264 1 Mitra P, Maceyka M, ... through doxorubicin-activated Sp1 in drug-resistant HL -60 ⁄ ADR cells Cancer Res 64 , 62 71 62 79 Takeda S, Mitsutake S, Tsuji K & Igarashi Y (20 06) Apoptosis occurs via the ceramide recycling pathway ... elements Mol Endocrinol 16, 1 269 –1279 Mitsutake S, Yokose U, Kato M, Matsuoka I, Yoo JM, Kim TJ, Yoo HS, Fujimoto K, Ando Y, Sugiura M et al 38 26 27 28 29 30 31 32 33 34 35 36 (2007) The generation...
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