... The Pragmatic Programmers, LLC was aware of a trademark claim, the designations have been printed in initial capital letters or in all capitals The Pragmatic Starter Kit, The Pragmatic Programmer, ... software, maintaining the hardware and software where the application runs, making sure that the data is kept safe and secure—none of that is your concern Inthe cloud, you buy software as a service ... messages Download basechat.py def main( ): room = ChatRoom( "Main" ) markcc = ChatUser("MarkCC") markcc.subscribe( "Main" ) prag = ChatUser("Prag") prag.subscribe( "Main" ) markcc.sendMessage( "Main" ,...
... Honkala, An optimal locating-dominating set inthein nite triangular grid, Discrete Math 306 (2006) 2670-2681 [6] I Honkala and T Laihonen, On identifying codes inthe triangular and square ... Constellation in Figure As we already remarked after introducing Rule 1, at most one of the codewords c5, d3 and e4 is in C2 , and the others are in C The vertices c4, d5 and e3 are all in N , and therefore ... Laihonen and S Ranto, Families of optimal codes for strong identification, Discr Appl Math 121 (2002) 203–213 [11] A Lobstein, Identifying, locating-dominating and discriminating codes in graphs (Internet...
... advertising by CPAs that was prohibited by the earlier codeInthe same year, the Auditing Standards Board issued a package of nine new Statements on Auditing Standards (dubbed expectation gap standards) ... disciplinary action (termination, suspension, and other) and by the source of action (automatic or hearing) Also provided are the averages per year These averages are calculated by dividing the raw ... of theCode by the AICPA members are rare The assumption is that all major cases are detected and adjudicated by the AICPA, state boards of accountancy, and state societies of CPAs There are,...
... CTGAGGTTACAGACAACTGTTC CCTTTGACATCGCAAGTGGATCA TTGAGGTGACAGACAATTGCCT TCTTTGACTTCTCAAACTGATCG GCGGCCGCCACCATGCATCATCACCATCAC CATGTCAGCCGTTTTGAACAC GCGGCCGCCACCATGCATCATCACCATCAC CATGTCAGCCGTCTTGAACAC RPE65c-His-Fwd ... GCGGCCGCCACCATGGTCAGCCGTTTTGAACAC GATATCTTATGGTTTGTACATCCCATGGAAAG GCGGCCGCCACCATGGTCAGCCGTCTTGAACAC AAGCTTCTAAGGTTTGTAGATGCCGTGGAG TGGGGAGGACTTTTATGCTGT CTTTTGTGTAGGTGGGATTCG CTGAGGTTACAGACAACTGTTC ... RPE65c inthe retina and its subcellular fractionation To analyze the cellular localization of zebrafish RPE65c inthe retina, we generated an antibody using a specific zebrafish RPE65c peptide, and the...
... side-chain of His210 increased with the decrease in size of the side-chain at residue 169 (Table and Fig 3A) However, the ASAs of Asp113 and His57 remained constant when the side-chain at residue ... aspartate inthe catalytic triad is not fully understood because several serine proteases not have an aspartate as the catalytic apparatus M NaCl However, for chymotrypsin-type serine proteases, the ... state B, active state above pH 6.3 side-chain at residue 210 is dispensable, as shown by the fact that H21 0A and H210S are as active as native API with VLK-MCA as a substrate (Table 1) This means...
... resource accounting and budgeting In Australia themain driver for change was the introduction of Accruals-based Outcome and Output Budgeting In Canada, the Office of the Auditor General and the Treasury ... staff and mangers to the tasks at hand Monitoring (collecting) performance data: Once indicators and targets are set, actual data for each indicator is collected at regular intervals Implementation ... space for explanation and justification of the ratings The information from these forms are entered into a central database and analyzed inthe Bank’s annual report on portfolio performance (ARPP)...
... sections and the ER21 antibody, which is made against a peptide containing the first 21 amino acids of the rat and human ERα (does not cross-react with ERβ), we also found predominant staining in efferent ... reabsorption This inhibition is mediated by a decrease inthe expression of NHE3 mRNA and protein and also decreases in carbonic anhydrase II (CAII) and aquaporin I (AQP-1) proteins There is also ... tract using ICC alone Autoradiography and estradiol binding assays indicate that ER is present inthe rat epididymis RT-PCR data also show that ERα is present in epididymal tissues [59,108] Therefore,...
... ¨ incubation with the M sexta clip- domain serine proteinases HP6 or proPO-activating proteinase-1 (data A not shown) Inthe absence of b-mercaptoethanol, Spatzle-C108 migrated to a position around ... ⁄ PAGE followed by silver staining demonstrated that this step effectively separated Spatzle-C108 from its pro-domain and the acti¨ vating proteinases, and that it remained as a disulfide linked ... hydrolyze the HP8 substrate Ile-Glu-Ala-Arg-p-nitroanilide (IEARpNA) [31] ProHP8Xa lacked IEARase activity, but after the zymogen was activated by factor Xa, IEARase activity increased significantly above...
... constants corresponding to apparent rate constants are obtained by fitting Eqn (1): DAbs ¼ a þ b eÀct ð1Þ where, DAbs is the variation of absorbance, a and b are amplitude parameters and c is the ... for each experiment Apart from these artifacts the distributions of the residuals show a good agreement between experimental data and the plot obtained by fitting The traces obtained are comparable ... classes according to their values, the analogues of ubiquinone and those of menaquinone, these last having larger differences of coefficients than the first This is not surprising, because menaquinols...
... 2005 FEBS BMP/activin pathway in Crassostrea gigas ted of its highly variable C-terminal domain after the terminal conserved arginine of the cytoplasmic serine ⁄ threonine kinase domain Sequences ... receptors are in bold and underlined, and the cysteine knot is boxed Also boxed are the transmembrane domain, the ATP binding site, the L45 loop and the serine ⁄ threonine kinase domain (B) The implied ... threonine kinase domain FEBS Journal 272 (2005) 3424–3440 ª 2005 FEBS 3427 BMP/activin pathway in Crassostrea gigas A Herpin et al A Crassostrea gigas C2 domain ALK-6 E fluviatilis C2 domain 77 Crassostrea...
... washing stage ligninand remaining chemicals are removed The depithed pulp is transported to the storage tank then pumped to a beater Waste paper and water are added into beater Here pulp and waste ... for the paper machines including washing wire and washing blanket was measured Then the water consumption for paper machine was calculated from flow rate, paper machine velocity and product amount ... machine The wastewater flowrate from beater cleaning and floor cleaning was not possible to measure Inthis case wastewater flowrate was assumed equal to water usage in each unit operation The wastewater...
... biosynthesis was repressed and metabolism was enhanced in animals exposed to an HFD with GBE50 Genes involved in fatty acid biosynthesis, such as Acacb, Acbd6 (acyl-CoA-binding domain containing ... Technologies, Santa Clara, CA, USA) Homemade cDNA microarrays containing 10 200 rat genes or ESTs were fabricated as previously described [29–31] The list of the genes on the microarray is available on the ... upregulated genes for an acyl-CoA synthetase member (Acsl1), pyruvate carboxylase (Pc), aspartoacylase (Acy3) and solute carrier family 25 member (Slc2 5a1 ) are involved in lipid biosynthesis, and the...
... Association The Democratic Party platform called for a national guarantee of personal deposits, following what several States had already done starting in 1907, and endorsed postal savings only as ... never spark a financial panic At any rate, the postwar period until the 1990s has been characterized by a nearly universal acceptance of an implicit government guarantee backing financial institutions' ... as well, when a percentage-point change inthe number of banking suspensions was associated with about a 0.6 percentage-point increase inthe postal savings share (chart 6).27 Chart Postal savings...
... industry and layoffs rampant in her company Sitting at Penn Station, sweating from the summer heat and waiting for his train home, Ryan fantasized about trading it all in and joining the Peace Corps ... looking for a job in an environment that was anything but friendly And Christina’s job THE MEETING [5] wasn’t looking all that stable, either, given the big changes inthe insurance industry and ... business and their issues At this point, much of the initial sales job is done.” Ryan thought for a moment, moving the remains of his steak around his plate, then asked, “Doesn’t the pain and...
... comparing measures taken at baseline (the beginning of treatment) and comparing them to measures taken at the end of treatment Increasingly there is a demand for psychologists inthe primary ... therapy and medication or medication alone Interventions Psychodynamic psychotherapy plus pharmacotherapy Comparison Groups Pharmacotherapy (pharmacotherapy and clinical management, including psychoeducation) ... during the maintenance phase Psychosocial interventions appear to have the greatest benefit in reducing risk of relapse and improving functioning during the maintenance phase A number of intensive...
... nized the lack of management format and mandate, resource constraints, and financial and professional motivation as barriers Managers did not seem to think that their own management capacity was an ... Measles-1 Many variables can cause poor rates of immunization including inadequate financing, poor vaccine quality, poor vaccination practices, and weak health care systems [7] but one of the most ... management inthe health facilities The doctor is appointed by the head of the policlinic, and the head of the policlinic is appointed by the Ministry of Property Management We have minimal say...
... and position inthe organization may be a contributing cause in these differences In Norway, the nurses have the same education as their managers, and very few of the managers of the municipal ... of the study and writing of the manuscript TF participated inthe analysis of the data, the sequence Page 10 of 12 alignment and writing of the manuscript All authors have read and approved the ... tables and analyses inthis research were valid inthe factor analysis The KMO and Test of Sphericity test the null hypothesis that the correlation matrix is valid These factor analyses show that the...
... a classical histological analysis, and diagnosed the ovarian cancer All authors read and approved the final manuscript Competing interests The authors declare that they have no competing interests ... epithelium of fetal ovaries, and might have been involved inthe manifestation of serous papillary adenocarcinoma inthis patient They expressed the analyzed markers of pluripotency SSEA-4 and ... serous papillary adenocarcinoma was diagnosed After hematoxylin-eosin staining some corpora albicans, atretic follicles, small inclusion cysts, and rete ovarii were observed Randomly, a proportion...
... analytes For the quantitation of the analytes, a 5-point (PAHs) and a 7-point (pharmaceuticals) internal standard calibration was used The limit of detection and the LOQ were calculated on the basis ... Stadtwerke Trier wastewater laboratory for providing samples and TOC data during the campaign They also thank Margret Roth and Michael Bayerle for their technical support inthe chemical analysis ... than that reported inthis paper Pharmaceuticals and PAHs The selection of the analyzed organic wastewater pollutants was based on their toxicological relevance in environmental studies and the...
... exchanges are a route request, a web page request or a packet acknowledgment IDRA creates the actual packet, encapsulates the information inthe payload and stores the resulting packet ina system-wide ... are added to the packet Delay-tolerant parameters can remain inthe waiting space for up to a per-parameter predefined period of time If no data have been relayed within the allowed waiting time, ... software services are dynamically combined to form ad hoc applications In regards to the internet of things, SOAs have two main disadvantages [32]: (1) SOAs focus mainly on higher layers rather...