their limitations and potential
báo cáo hóa học:" Ovarian cancer mouse models: a summary of current models and their limitations" docx
Ngày tải lên :
20/06/2014, 07:20
... technique of isolating and culturing MOSE cells, showing that MOSE cells can spontaneously transform in vitro with repeated passages and have tumorigenic capacity as they formed tumors and hemorrhagic ... carcinomatosis, and extensive ascites fluid production between 80 to 90 days post-exposure The cytological and architectural features resembled serous carcinoma Interaction between ID8 cells and the ... proliferative and survival markers, including phosphorylated Akt, proliferating cell nuclear antigen (PCNA), and Bcl-2 Vascular endothelial growth factor (VEGF) levels were also increased in the serum and...
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Genetic polymorphisms of matrix metalloproteinases and their inhibitors in potentially malignant and malignant lesions of the head and neck potx
Ngày tải lên :
10/08/2014, 05:21
... Sterlinct and Werb 2001; Overall 2002; Visse and Nagase 2003) tant due to their ability to degrade the ECM and basement membranes [24] lated at the transcriptional and post-transcriptional levels and ... protein levels Regulation of MMPs in potentially malignant and malignant head and neck lesions Polymorphism of MMPs in potentially malignant and malignant head and neck lesions The MMPs are regulated ... evolved for the MMPs in potentially malignant and malignant lesions of the head and neck Further research is required for the development of their potential diagnostic and therapeutic possibilities...
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Báo cáo y học: "Direct electrochemical analyses of human cytochromes b5 with a mutated heme pocket showed a good correlation between their midpoint and half wave potentials" doc
Ngày tải lên :
10/08/2014, 05:21
... -25 -20 -15 Half-wave potential (mV) Figure Correlations between the midpoint potential and half-wave potential (E1/2) for HLMWb5 and its site-specific mutants The half-wave potentials (E1/2) were ... incorporated Table Half-wave potentials of HLMWb5 and its site-specific mutants in comparison with various animal cytochrome b5 and their site-specific mutants Samples half-wave potential (mV) (vs SHE) ... potential and midpoint potential Interestingly, when the midpoint potential measured in the absence of poly-L-lysine was plotted against the half-wave potential for each of HLMWb5 and mutants,...
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LIMITATIONS AND DIRECTION FOR FURTHER RESEARCH
Ngày tải lên :
13/04/2013, 10:31
... Brand choice brand loyalty, brand switching • Brand satisfaction which brands consumers think they would buy next? Which others might they buy? Which brands would they not consider buying and ... what people like and dislike in general about brands in the product category and about specific key brands That is, we want to know brand satisfactions, and, even more important, their dissatisfactions ... learn about the new brand or come to try the new brand or even other brands not their own? Was their own brand out-of-stock? Did they respond to some special offer or promotion and decided they liked...
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The Treatments of Social Phobia - Their Nature and Effects
Ngày tải lên :
01/11/2013, 08:20
... becoming less anxious and less handicapped and being more and better socially active remains uncertain Similarly, no studies to date have systematically observed the relapse rate on and after stopping ... phobia is in demand; a market in various services and products has sprung up to satisfy it Naturally, providers attempt to draw attention to their wares and to drum up more demand (e.g Gilbody, ... dealing with their real-life social/interpersonal circumstances and to use them in situations very much a part of their daily lives Admitting to being keen or red-faced, volunteering, and speaking...
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RFID current applications and potential economic benefits (IBM)
Ngày tải lên :
04/12/2013, 15:08
... to help organizations aggregate, analyze and act upon data and dynamically adjust operations in response to changes in their business Wireless Broadband & Sensing Solutions ibm.com/industries/wireless/ ... processes across their company and with key partners, suppliers & customers …positioning them to respond with speed to customer demand, market opportunity or external threats Wireless Broadband & Sensing ... Track & Trace, Military and defense tracking Monitor the movement and use of valuable equipment and personal resources Security & Access Control Includes: Access control and tracking, Animal tracking,...
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Tài liệu Materials, Their Properties and Uses doc
Ngày tải lên :
13/02/2014, 09:20
... sandpaper The chief types of abrasive sand include sandblast sand, glass-grinding sand, and stone-cutting sand Sand for stone sawing and for marble and glass grinding is usually ungraded, with no ... ABRASIVE SAND Any sand used for abrasive and grinding purposes, but the term does not include the sharp grains obtained by crushing quartz and used for sandpaper The chief types of abrasive sand include ... have tough, uniform grains Chats are sand tailings from the Missouri lead ores, used for sawing stone Banding sand is used for the band grinding of tool handles and for the grinding of plate glass,...
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Tài liệu FUNGI: THEIR NATURE AND USES ppt
Ngày tải lên :
13/02/2014, 12:20
... parasitic, distorting, and in many cases ultimately destroying, their host, burrowing within the tissues, and causing rust and smut in corn and grasses, or even more destructive and injurious in such ... closer observation, and more and more education of the eye to see, and the mind to appreciate, relationships and distinctions We have already assumed that fungi are duly and universally admitted, ... and the foliage, it is to some extent possible to understand the connection between parasitic plants like fungi, which not derive their support from the constructive energy of their fronds, and...
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Tài liệu Development Banks: Their role and importance for development ppt
Ngày tải lên :
16/02/2014, 11:20
... savings and time deposits, acquire liabilities that are individually small and protected from income and capital risk, are of short maturity and are substantially liquid in nature On the other hand, ... is expected to autonomously evolve and is left unregulated, market signals would determine the allocation of investible resources and therefore the demand for and the allocation of savings intermediated ... investments involve long gestation lags and take long to go into commercial production and return a profit Most savers, on the other hand, would not like to lock up their capital for long periods especially...
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Tài liệu Báo cáo khoa học: Mixed lineage leukemia: roles in human malignancies and potential therapy pdf
Ngày tải lên :
16/02/2014, 14:20
... leukemia patients and collected a total of 64 different MLL fusion partners The analyzed MLL fusion alleles were classified according to their occurrence in ALL and AML patients and their putative ... this important question, a careful and systematic examination of available MLL fusion alleles (n > 60) is necessary to identify and analyze their specific oncogenic potential The multitude of MLL ... partner genes are categorized in Fig according to their cellular localization and their putative function Twenty-five of them represent nuclear proteins and 33 represent cytosolic proteins; one fusion...
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FACING THE REALITY OF DRUG-RESISTANT TUBERCULOSIS: CHALLENGES AND POTENTIAL SOLUTIONS IN INDIA pot
Ngày tải lên :
05/03/2014, 11:20
... Control in China, 31 Historical Perspective on TB and MDR TB Control Efforts, 32 Global Challenges and Potential Solutions, 33 Potential Innovations and Action Items, 36 29 PREVENTING TRANSMISSION ... Migrant and Refugee Populations, 63 Case Studies in Cambodia and Ethiopia, 64 Potential Innovations and Action Items, 67 55 COMBATING DRUG-RESISTANT TB THROUGH PUBLIC–PRIVATE COLLABORATION AND INNOVATIVE ... drug-resistant strains of TB and to discuss innovative strategies for advancing and harmonizing local and international efforts to prevent and treat drug-resistant TB.2 HISTORY AND DIMENSIONS OF THE...
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Health in All Policies Prospects and potentials ppt
Ngày tải lên :
05/03/2014, 21:20
... generation and capacity building: organizations and institutions involved 242 Table 12.6 Ministries whose policies were the subject of health impact assessments in the Netherlands and Finland 247 ... between the healthy and the sick, the better off and the poor, the young and the old, the employed and the unemployed may be challenged As an effect, the universal availability and accessibility ... original texts and their use of the terms REFERENCES Bloom D, Conning D, Jamison D Health, wealth and welfare Finance and Development, 2004, 41(1):10–15 Commission on Macroeconomics and Health Macroeconomics...
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Continuing Challenges and Potential for Collaborative Approaches to Education Reform pot
Ngày tải lên :
06/03/2014, 01:22
... grantees’ progress and accomplishments and found some to be seriously lacking 4 Continuing Challenges and Potential for Collaborative Approaches Using the initial RAND study and foundation findings, ... understand the social, political, and economic context surrounding the collaborative and different educational issues and initiatives under way, and collected plans, brochures, flyers, and other ... Continuing Challenges and Potential for Collaborative Approaches Hogue (1994), Keith (1993), Mattessich and Monsey (1992), Himmelman (1996), Lieberman and McLaughlin (1992), and Winer and Ray (1994)...
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Báo cáo khoa học: Alternative splicing: role of pseudoexons in human disease and potential therapeutic strategies pot
Ngày tải lên :
06/03/2014, 09:22
... what is an exon and what is an intron [21] Where pseudoexon sequences come into the story? Central to the issue of deciding what is an exon and what is an intron is the question of their origin, ... term we refer to any nucleotide sequence between 50 and 200–300 nucleotides in length with apparently viable 5¢ and 3¢ splice sites (5¢ss and 3¢ss) at either end] Presently, there is evidence ... identified even in well-known and studied genes, such as the DMD gene [35] Second, our failure to observe their use in normal conditions may also be due to the fact that their inclusion can intentionally...
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European Large Lakes – Ecosystem changes and their ecological and socioeconomic impacts doc
Ngày tải lên :
06/03/2014, 18:21
... Ecosystem changes and their ecological and socioeconomic impacts Developments in Hydrobiology 199 Series editor K Martens European Large Lakes Ecosystem changes and their ecological and socioeconomic ... nitrite nitrogen and nitrate nitrogen and the sum of both by ow analysis and spectrometric detection Gulati, R D & E van Donk, 2002 Lakes in the Netherlands, their origin, eutrophication and restoration: ... large lakes and their ecological and socioeconomic impacts The ELLS grew out of the International Lake Ladoga Symposia organized in 1993, 1996, 1999, and 2002, which improved our understanding of...
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Báo cáo khoa học: The chaperone and potential mannan-binding lectin (MBL) co-receptor calreticulin interacts with MBL through the binding site for MBL-associated serine proteases pdf
Ngày tải lên :
07/03/2014, 05:20
... opsonization and phagocytosis (e.g the C3b receptor) Receptors for MBL and C1q are also assumed to play a role in opsonization and clearance and have been the subject of intensive research Several candidate ... possess Ca2+ binding, lectin-like and polypeptide binding properties [61–67] Calreticulin has been reported to be a candidate co-receptor for the collectins and C1q and to be present on cell surfaces ... target/apoptotic cell recognition depends on multiple factors and ligands, and that it has an inherent redundancy, in order to achieve maximal specificity and safety in self/non-self discrimination Thus, the...
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Báo cáo khoa học: SHP-1 dephosphorylates 3BP2 and potentially downregulates 3BP2-mediated T cell antigen receptor signaling ppt
Ngày tải lên :
07/03/2014, 12:20
... tail that bears three potential phosphorylated tyrosine residues (Tyr538, Tyr543 and Tyr566) We mutated each of them and cotransfected the resulting mutants with 3BP2–myc and Lck into 293T cells ... buffer and subjected to immunoprecipitation and western blot as described analysis of the anti-myc immunoprecipitants showed that 3BP2 was phosphorylated and dephosphorylated by wild-type SHP-1, and ... signaling On the other hand, SHP-1 is phosphorylated on Tyr566 at the C-terminus and thereby recruits 3BP2 through SH2 domain interaction This leads to dephosphorylation of 3BP2 and termination of...
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Retail Consolidation and Produce Buying Practices: A Summary of the Evidence and Potential Industry and Policy Responses pot
Ngày tải lên :
07/03/2014, 13:20
... practices and their potential market power in the procurement and sale of several produce commodities In particular, Richards and Patterson examine fresh orange, fresh grapefruit, table grape, and ... advertising allowances and other merchandising payments and services, which seek to define the applicability of Sections 2(d) and 2(e) of Robinson-Patman to advertising and merchandising.10 The new ... practices, and other anti-competitive activities have been judged outside protection of the act and are prosecutable under the Sherman Act [U.S v Maryland Coop Milk Producers, Inc and Maryland and Virginia...
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Database Support for Matching: Limitations and Opportunities pdf
Ngày tải lên :
07/03/2014, 14:20
... between n1’ and n2’ if there was an edge between the original two groups which they represent (Connecting new nodes to source and sink) add an edge between s’ and n1’, and between n2’ and t’ (Assign ... as usual, the relational θ join of R and S For now, assume that θ is a conjunction of the form R.a1 op1 S.a1 AND R.a2 op2 S.a2 AND, …, AND R.ap-1 opp-1 S.ap-1 AND R.ap opp S.ap, where op1 through ... loss of generality, let θ be of the form R.a1 = S.a1 AND R.a2 = S.a2 AND, …, AND R.ak = S.ak AND R.ak+1 < S.ak+1 Now within each group G, all R and S tuples match each other on the k equality predicates;...
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