... opportunity costof going to a movie is a the price ofthe ticket b the price ofthe ticket plus thecostof any soda and popcorn you buy at the theater c the total cash expenditure needed to go to the ... seats, thecostof adding one more passenger is tiny The average costof flying a passenger is $500, but the marginal cost is merely thecostofthe bag of peanuts and can of soda that the extra ... point A, the opportunity costof 100 cars is 200 computers Put another way, the opportunity costof each car is two computers Notice that the opportunity costof a car equals the slope ofthe production...
... regimes the level of redistributive spending should be minimal The third tenet ofthe formal voting theory emphasizes the importance ofthe form ofthe voting game’ On the contrary, there are ... increases The ultimate level of taxes becomes smaller than thecostof repression On the contrary, when the redistributive demands ofthe worse-off citizens on the rich are particularly intense, the ... in the analysis of tax level and tax design They may interact with the main macroeconomic variables, such as the level of GDP per worker, the openness ofthe economy, the level of debt and the...
... Outline The Economics of Taxation • The role of taxation • The main types of taxation Outline The Economics of Taxation • The role of taxation • The main types of taxation The Efficiency Costof ... Marginal costof public funds Outline The Economics of Taxation • The role of taxation • The main types of taxation The Efficiency Costof Taxation • Marginal excess burden • Marginal costof public ... capitalisation Outline The Economics of Taxation • The role of taxation • The main types of taxation The Efficiency Costof Taxation • Marginal excess burden • Marginal costof public funds Tax...
... both in the host country ofthe Why countries need Double Tax Treaties? investment and in the residence country ofthe investor), by allocating taxing rights over this income between the two ... Objectives ofthe 2011 Update • Take into account recent developments in the area of international tax policies of both developing and developed countries • Seek further consistency with the OECD ... the priorities of developing countries • Further clarify and improve the operation of provisions aimed to prevent double taxation over income from cross-border investments Main features of the...
... onethird of all mutations in the BTK gene are missense and some of these reduce the stability ofthe protein This is exemplified by mutations in the BTK motif ofthe Tec homology (TH) domain [18] ... identify individuals with mild disease, thereby providing the missing data The phenotype of XLA and the potential of BTK and ITK inhibitors The outcome of defective BTK signaling in humans has ... the expression of ITK is extremely low and often undetectable in immunoblot analysis The activation of CD4+ cells, however, dramatically induces transcription ofthe ITK gene and is key for the...
... indication ofthe lack of economic freedom in the compilation ofthe index, the average score ofthe Nordic countries on the overall economic freedom index is only slightly higher than that ofthe Anglo-American ... geography or other characteristics beyond the control ofthe country’s government, by the method used to aggregate individual indicators, by the comparability ofthe data, and by the purpose ofthe evaluation ... equal society bears fewer ofthe costs of social stratification such as increased health costs, crime control costs, and thecostof inner city decay The above review of social indicators suggests...
... outside the home countries At the same time, the share of manufacturing in most ofthe world’s economies is declining, and that of services is increasing The net result of these two forces, and ofthe ... thirty days ofthe transmittal ofthe manuscript, the report may be published If at the end of that period any member ofthe manuscript committee withholds his approval, the President shall then notify ... Relation ofthe Directors to the Work and Publications ofthe National Bureau of Economic Research The object ofthe National Bureau of Economic Research is to ascertain and to present to the public...
... shift ofthe displacement curve and by the lower amount of radioactivity bound in the absence of competitor (in spite ofthe lack of statistically significant differences in the number of binding ... to the responsive HBL cells The lack of functional coupling of these cell lines, particularly of DOR cells homozygous for the wild-type MC1R, is therefore perplexing and will be the subject of ... receptors The electrophoretic mobility of molecular weight markers is shown on the left, and the molecular weight ofthe specific bands is shown on the right (expressed in kDa) The specificity of the...
... controlled by the methylation-free promoter One ofthe common features of these plants free from S-PTGS is the attenuated expression ofthe transgene, and therefore the threshold theory has been ... analysis ofthe transgene sequence (A) Degree of cytosine methylation at the END1 region ofthe El2 promoter (B) Degree of cytosine methylation at the END2 region ofthe El2 promoter (C) Degree of cytosine ... with the generation of transgene siRNAs and, also, DNA methylation in the transgene locus [16,17] These results imply the existence of a threshold concentration of transcripts for the onset of...
... it is therefore likely that the outcome ofthe inhibition of aggrecanase activity in tendon is the retention of large proteoglycans within the extracellular matrix ofthe tissue [22–27] The mechanism ... inclusion of these sulfated agents there was significant inhibition (40%) of rate of loss of 35S-labeled large proteoglycans from the matrix by the end ofthe culture period Similarly, by day 10 of culture, ... appearing in the medium was suppressed by the inclusion ofthe sulfated polysaccharides At the end ofthe culture period, both CaPPS and heparin reduced the appearance of [35S]sulfate in the culture...
... firms; the profits of other firms are taxed as part ofthe personal income of their owners The computation ofthe corporate income tax liability of a firm follows a number of rules that concern the ... of congestion on road R equals the sum ofthe toll and thecostof congestion on road R1 In equilibrium, thecostofthe toll on R1 is balanced by the higher costof congestion on road R A second ... reduces the value of land one for one, since the supply of land is assumed to be inelastic Therefore the agents who own land when the tax is announced bear the whole burden ofthe tax On the other...
... mutation in the GJB2 gene with either recessive or unclear pathogenicity, despite direct sequencing ofthe entire coding region ofthe gene [12-14] The ratio of a 309-kb deletion involving the GJB6 ... only one allele ofthe coding region ofthe GJB2 gene [41] It is also lower than the value of 4.6% among Brazilian patients with one pathogenic GJB2 mutation [42] The percentage ofthe IVS1+1G>A ... pathogenic mutation in the GJB2 gene may have another as yet unidentified pathogenic mutation in the promoter region or other noncoding regions of GJB2 To evaluate the impact ofthe IVS1+1G>A splice-site...
... better understand the mechanism of action of HRSV neutralizing antibodies and the impact of resistance to these antibodies upon the fusion activity ofthe F protein A summary of these results is ... high degree of conservation, it was somewhat surprising that the functional analysis ofthe fusion activity ofthe panel of mutations described here revealed that the fusion activity ofthe F protein ... mutagenesis ofthe HRSV F protein AD and RS participated in the design, oversight ofthe conduct ofthe experiments, and interpretation ofthe results All authors have read and approved the final...
... altogether, these data indicate the existence of a mechanism for the global control ofthe 11q23 CD3 genes cluster that is likely to be critical in modulating the expression of these genes during the ... paves the way for malignant transformation[10] Since dysregulation of calcium flux after Tcell activation can be one ofthe consequences ofthe lack of TCR/CD3 expression[11] the loss of TCR/CD3 ... This demonstrates that the loss of CD3γ is not due to a defect in factors binding to the CD3γ promoter region and rather suggests a lack of accessibility of these factors to the promoter regions...
... distribution of Tax-2 molecules was analyzed in the presence and in the absence of CIITA In the absence of CIITA, Tax-2 localizes both and in the cytoplasm and in the nucleus of 293T cells often with ... region of CIITA Furthermore, these results strongly suggest that interaction between the N-terminal, but not the C-terminal, part of CIITA, and Tax-2 is responsible ofthe biological effect of CIITA ... most likely in the CIITA-NF-YB molecular complex, is at the basis ofthe functional inactivation of Tax-2 leading to the inhibition of HTLV-2 retrovirus replication Further studies of subcellular...
... assess the optimal combination of amplifiers, loud speakers, number of firings (each click ofthe mouse ofthe computer provided a single firing), their sound intensity and the mode of their delivery ... day, when anesthesia had worn off, a single injection of 100 mg/kg of furosemide was administered intraperiteoneally (IP) to the mice ofthe experimental group and the mice ofthe control group ... section The diaphragm ofthe speaker was 16 cm above the floor ofthe mice enclosure, so that the net volume ofthe exposure chamber was 9920 cm Mice in one group (n = 10) received a single of injection...
... better understand the mechanism of action of HRSV neutralizing antibodies and the impact of resistance to these antibodies upon the fusion activity ofthe F protein A summary of these results is ... high degree of conservation, it was somewhat surprising that the functional analysis ofthe fusion activity ofthe panel of mutations described here revealed that the fusion activity ofthe F protein ... mutagenesis ofthe HRSV F protein AD and RS participated in the design, oversight ofthe conduct ofthe experiments, and interpretation ofthe results All authors have read and approved the final...
... altogether, these data indicate the existence of a mechanism for the global control ofthe 11q23 CD3 genes cluster that is likely to be critical in modulating the expression of these genes during the ... paves the way for malignant transformation[10] Since dysregulation of calcium flux after Tcell activation can be one ofthe consequences ofthe lack of TCR/CD3 expression[11] the loss of TCR/CD3 ... This demonstrates that the loss of CD3γ is not due to a defect in factors binding to the CD3γ promoter region and rather suggests a lack of accessibility of these factors to the promoter regions...
... distribution of Tax-2 molecules was analyzed in the presence and in the absence of CIITA In the absence of CIITA, Tax-2 localizes both and in the cytoplasm and in the nucleus of 293T cells often with ... region of CIITA Furthermore, these results strongly suggest that interaction between the N-terminal, but not the C-terminal, part of CIITA, and Tax-2 is responsible ofthe biological effect of CIITA ... most likely in the CIITA-NF-YB molecular complex, is at the basis ofthe functional inactivation of Tax-2 leading to the inhibition of HTLV-2 retrovirus replication Further studies of subcellular...
... because ofthe increase in the milk production The importance of a relatively early resumption of cyclicity as a predictor for good reproductive ability has often been emphasized [7,16] Nevertheless, ... In the present study, an association of high milk production with the occurrence of ovarian cysts and the decrease in the body condition was noticed These findings have also been found by other ... with the intrauterine application of antibiotics A better functionality ofthe endometrium and a reduction in the endotoxin stress caused by the endometritis could be the explanation for the clinical...